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  • Small Cell Lung Cancer

    Dana-Farber/Brigham and Women's Cancer Care

    About Small Cell Lung Cancer

    What is Small Cell Lung Cancer?

    Small cell lung cancer affects about 15% of lung cancer patients. Small cell lung cancer usually starts in the breathing tubes (bronchi) in the center of the chest. The cancer cells are small, but they usually grow very quickly and create large tumors. These tumors often spread rapidly (metastasize) to other parts of the body, including the brain, liver, and bone.

    PDQ image - Anatomy of the respiratory system, showing the trachea and both lungs and their lobes and airways

    At Dana-Farber/Brigham and Women's Cancer Center (DF/BWCC), our dedicated thoracic team of radiologists, pathologists, medical oncologists, surgeons and radiation oncologists work together to determine:

    1. Whether you have cancer at all (there are other disorders that can look like cancer but have very different treatments and outcomes);
    2. What type of cancer you have;
    3. What set of treatments are likely to be most effective for your individual cancer.

    Risk Factors for Small Cell Lung Cancer

    Anything that increases a person's chance of developing a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesn't mean that you will not get cancer.

    Risk factors for small cell lung cancer include:

    • Smoking cigarettes, pipes, or cigars, now or in the past
    • Being exposed to secondhand smoke
    • Being exposed to asbestos or radon

    Symptoms of Small Cell Lung Cancer

    Sometimes lung cancer does not cause any symptoms and is found during a routine chest X-ray.

    Small cell lung cancer is often asymptomatic initially. As a result, it often spreads to other parts of the lung or to other organs before it is detected. As the cancer progresses, possible signs and symptoms include coughing, chest pain, and shortness of breath.

    Consult your doctor if any of the following occur:

    • A cough that doesn't go away
    • Shortness of breath or trouble breathing
    • Chest pain that doesn't go away
    • Wheezing
    • Coughing up blood
    • Hoarseness
    • Swelling of the face and neck
    • Loss of appetite
    • Weight loss for no known reason
    • Unusual tiredness

    Find out more about small cell lung cancer from the National Cancer Institute.

    Read our Insight blog for information and inspiration about treatment for lung cancer at Dana-Farber.

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  • Make an Appointment

    • For adults:
      877-442-3324 (877-442-DFCI)

    • Quick access:
      Appointments as soon as the next day for new adult patients


    • For children:
      888-733-4662 (888-PEDI-ONC)

    • Make Appointment Online
  • Lung Cancer Treatment

    • Learn more about our treatment options for patients with lung cancer, mesothelioma, and other chest wall cancers.
  • Find a Lung Cancer Clinical Trial

  • Women's Lung Cancer Program

    • The Women's Lung Cancer Program at Dana-Farber/Brigham and Women's Cancer Center offers a wide range of clinical and support services for women who have been diagnosed with lung cancer.
  • Health Library Resources

  • Lung Cancer News