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  • The Bing Center for Waldenström's Macroglobulinemia

    Dana-Farber/Brigham and Women's Cancer Care

    The Bing Center for Waldenström's Macroglobulinemia provides care and new therapies through clinical trials to patients with Waldenström's macroglobulinemia and related Immunoglobulin M (IgM) disorders.

    About the Center

    The Bing Center for Waldenström's Macroglobulinemia provides a comprehensive range of services for patients with Waldenström's macroglobulinemia, including:


    The Treatment Team

    The Bing Center for Waldenström's Macroglobulinemia encompasses a large, international team of laboratory-based and clinical investigators who are striving to find more effective therapies for Waldenström's macroglobulinemia and, someday, a cure.

    Steven Treon, MD, PhD

    Waldenström's Macroglobulinemia Leadership

    Steven P. Treon, MD, PhD, director, Bing Center for Waldenström's Macroglobulinemia
    Treon's main research interests focus on understanding the genetic basis and pathogenesis of Waldenström's and the development of novel therapeutics. He serves on the editorial boards of Journal of Clinical Oncology, Blood, Clinical Cancer Research, and The Lancet. He has been honored with several research and academic awards, including the Robert A. Kyle Award for Waldenström's.

    Jorge Castillo, MD

    Waldenström's Macroglobulinemia Physician

    Jorge J. Castillo, MD
    Castillo's research studies the various risk factors that could be associated with an increased risk of developing hematologic malignancies. He has run a series of investigator-initiated prospective clinical trials using non-chemotherapeutic regimens, and has developed several multi-institutional efforts to study Waldenström's macroglobulinemia and other lymphomas. His work has been published in Journal of Clinical Oncology, Blood, Leukemia, Cancer, British Journal of Haematology, and Leukemia and Lymphoma.

    Toni Dubeau, NP

    Waldenström's Macroglobulinemia Nursing

    Toni Dubeau, NP
    Dubeau joined the Waldenström's team to foster long-term relationships with patients in this setting. Before her work at Dana-Farber, she spent 13 years at Brigham and Women's Hospital caring for patients in a variety of settings, including bone marrow transplant and cardiology.

    Patricia Severns, NP

    Clinical Research

    Each patient's care combines the finest treatments currently available for Waldenström's macroglobulinemia with innovative new therapies based on research discovered through the collaboration of the center's laboratories and many other scientists from around the world.

    The Bing Center for Waldenström's Macroglobulinemia offers patients access to a wide range of clinical research trials. The main goal of clinical research at the Bing Center for Waldenström's Macroglobulinemia is to swiftly and efficiently take discoveries made in the laboratory to the clinic where they can benefit the health and well-being of the patient.

    This include studies aimed at improving the outcomes of patients undergoing biological therapies using agents in trials such as Rituxan and bortezomib that attempt to kill Waldenström's macroglobulinemia tumor cells directly. The center also has clinical research trials evaluating supportive therapies like statins and phosphodiesterase inhibitors to help understand the mechanics of the disease.

    Contact Us

    New Patients

    Waldenström's Macroglobulinemia: 617-632-3823 or 617-632-5138, or use this online form to make an appointment.

    You may schedule your first appointment for as soon as the next day. After scheduling, one of our nurses will call you to answer your questions and help you prepare for the appointment.

    Current Patients

    Contact your doctor directly, or for general inquiries, call the Hematologic Malignancies program at 617-632-6140.



    Mailing address

    Hematologic Malignancies Division
    Dana-Farber Cancer Institute
    450 Brookline Avenue
    Boston, MA 02215

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    • New adult Waldenström's Macroglobulinemia patients:
      617-632-3823 or 617-632-5138
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  • Waldenström's online community

    • Join the Dana-Farber Waldenström's Macroglobulinemia community on CancerConnect for support and information from others affected by this disease.
  • Online Resource for Precision Cancer Medicine

    • Clinicians at Dana-Farber/
      Brigham and Women's Cancer Center are now armed with specialized tests to create a precise "tumor profile" for each patient's cancer. Learn about the latest thinking in precision cancer medicine for certain types of blood cancers and explore a searchable database of clinical trials that focus on targeted therapies by disease, gene, and mutation.