Rachel A. Freedman, MD, MPH

Rachel A. Freedman, MD, MPH

Medical Oncology

Contact Information

Office Phone Number

617-632-3800

Fax

617-632-1930

Appointments

617-632-2175 (new patients)
617-632-3800 (established patients)

Biography

Rachel A. Freedman, MD, MPH

Dr. Rachel Freedman is a medical oncologist and clinical researcher at DFCI in the Breast Oncology Program.  In addition to seeing patients with breast cancer, her research focuses on improving the care of vulnerable patient populations who are under-represented in clinical trials and who are at risk for worse breast cancer outcomes, including older women and those who face challenges in access to care.  In addition, she is interested in novel therapeutics, serving as the Principal Investigator for several clinical trials.  She is also the founder and Director of the Program for Older Adults with Breast Cancer at DFCI.  Dr. Freedman joined the faculty at DFCI in 2009.  She studied at Georgetown University School of Medicine and obtained her master's in public health at the Harvard University T.H. Chan School of Public Health.  Her research has been funded by Susan G Komen, ACS, NCI, Gateway for Cancer Research, METAvivor, and the Alliance for Clinical Trials Foundation.

Researcher

Physician

Medical Director, DFCI Collaborative and Strategic Alliances
Senior Physician
Associate Professor of Medicine, Harvard Medical School

Centers/Programs

Diseases Treated

Board Certification

  • Internal Medicine, 2006
  • Medical Oncology, 2008

Fellowship

  • Dana-Farber/Partners CancerCare, Medical Oncology

Residency

  • Beth Israel Deaconess Medical Center, Internal Medicine

Medical School

  • Georgetown University School of Medicine

Publications

    • Mortality Risks Over 20 Years in Men With Stage I to III Hormone Receptor-Positive Breast Cancer. JAMA Oncol. 2024 Feb 29. View in: Pubmed

    • ASO Visual Abstract: Trends in Locoregional Therapy in Older Women with Early-Stage Hormone Receptor-Positive Breast Cancer by Frailty and Life Expectancy. Ann Surg Oncol. 2024 02; 31(2):1021-1022. View in: Pubmed

    • ASO Visual Abstract: Racial and Ethnic Disparities in Outcomes after Breast-Conserving Therapy and Endocrine Therapy for DCIS-A Post Hoc Analysis of the NSABP B-35 Randomized, Clinical Trial. Ann Surg Oncol. 2024 02; 31(2):1010-1011. View in: Pubmed

    • ASO Visual Abstract: Racial Disparities in Locoregional Recurrence in Postmenopausal Patients with Stage I-III, Hormone Receptor-Positive Breast Cancer Enrolled in the NSABP B-42 Clinical Trial. Ann Surg Oncol. 2024 01; 31(1):391-392. View in: Pubmed

    • Falls prechemotherapy and toxicity-related hospitalization during adjuvant chemotherapy for breast cancer in older women: Results from the prospective multicenter HOPE trial. Cancer. 2024 03 15; 130(6):936-946. View in: Pubmed

    • Trends in Locoregional Therapy in Older Women with Early-Stage Hormone Receptor-Positive Breast Cancer by Frailty and Life Expectancy. Ann Surg Oncol. 2024 Feb; 31(2):920-930. View in: Pubmed

    • Racial and Ethnic Disparities in Outcomes After Breast-Conserving Therapy and Endocrine Therapy for DCIS: A Post-Hoc Analysis of the NSABP B-35 Randomized Clinical Trial. Ann Surg Oncol. 2023 Dec; 30(13):8404-8411. View in: Pubmed

    • Racial Disparities in Locoregional Recurrence in Postmenopausal Patients with Stage I-III, Hormone Receptor-Positive Breast Cancer Enrolled in the NSABP B-42 Clinical Trial. Ann Surg Oncol. 2023 Dec; 30(13):8320-8326. View in: Pubmed

    • Inequities in referrals to a breast cancer risk assessment and prevention clinic: a mixed methods study. BMC Prim Care. 2023 08 25; 24(1):165. View in: Pubmed

    • Clonal hematopoiesis in older patients with breast cancer receiving chemotherapy. J Natl Cancer Inst. 2023 08 08; 115(8):981-988. View in: Pubmed

    • Estimating mortality in women with triple-negative breast cancer: The 'ESTIMATE triple-negative' tool. Eur J Cancer. 2023 08; 189:112930. View in: Pubmed

    • Racial and Ethnic Disparities in Locoregional Recurrence Among Patients With Hormone Receptor-Positive, Node-Negative Breast Cancer: A Post Hoc Analysis of the TAILORx Randomized Clinical Trial. JAMA Surg. 2023 06 01; 158(6):583-591. View in: Pubmed

    • Association of Surgery With Frailty Status in Older Women With Early-Stage Breast Cancer. JAMA Surg. 2023 06 01; 158(6):664-666. View in: Pubmed

    • Identifying Patterns and Barriers in OncotypeDX Recurrence Score Testing in Older Patients With Early-Stage, Estrogen Receptor-Positive Breast Cancer: Implications for Guidance and Reimbursement. JCO Oncol Pract. 2023 08; 19(8):560-570. View in: Pubmed

    • Breast cancer treatment receipt and the role of financial stress, health literacy, and numeracy among diverse breast cancer survivors. Breast Cancer Res Treat. 2023 Jul; 200(1):127-137. View in: Pubmed

    • Survival in male breast cancer over the past 3 decades. J Natl Cancer Inst. 2023 04 11; 115(4):421-428. View in: Pubmed

    • Infrastructure to Support Accrual of Older Adults to National Cancer Institute Clinical Trials. J Natl Cancer Inst Monogr. 2022 12 15; 2022(60):151-158. View in: Pubmed

    • Low-Intensity Adjuvant Chemotherapy for Breast Cancer in Older Women: Results From the Prospective Multicenter HOPE Trial. J Clin Oncol. 2023 01 10; 41(2):316-326. View in: Pubmed

    • Treatment discontinuation, patient-reported toxicities and quality-of-life by age following trastuzumab emtansine or paclitaxel/trastuzumab (ATEMPT). NPJ Breast Cancer. 2022 Nov 30; 8(1):127. View in: Pubmed

    • Breast cancer knowledge and understanding treatment rationales among diverse breast cancer survivors. Breast Cancer Res Treat. 2022 Dec; 196(3):623-633. View in: Pubmed

    • 'ADVANCE' (a pilot trial) ADjuVANt chemotherapy in the elderly: Developing and evaluating lower-toxicity chemotherapy options for older patients with breast cancer. J Geriatr Oncol. 2023 Jan; 14(1):101377. View in: Pubmed

    • Assessment of Oncologists' Perspectives on Omission of Sentinel Lymph Node Biopsy in Women 70 Years and Older With Early-Stage Hormone Receptor-Positive Breast Cancer. JAMA Netw Open. 2022 08 01; 5(8):e2228524. View in: Pubmed

    • Acceptability of a companion patient guide to support expert consensus guidelines on surveillance mammography in older breast cancer survivors. Breast Cancer Res Treat. 2022 Sep; 195(2):141-152. View in: Pubmed

    • Surveillance mammography in older breast cancer survivors: Current practice patterns and patient perceptions. J Geriatr Oncol. 2022 09; 13(7):1038-1042. View in: Pubmed

    • Estimating long-term mortality in women with hormone receptor-positive breast cancer: The 'ESTIMATE' tool. Eur J Cancer. 2022 09; 173:20-29. View in: Pubmed

    • Development of a workflow process mapping protocol to inform the implementation of regional patient navigation programs in breast oncology. Cancer. 2022 07 01; 128 Suppl 13:2649-2658. View in: Pubmed

    • Surveillance mammography after treatment for male breast cancer. Breast Cancer Res Treat. 2022 Aug; 194(3):693-698. View in: Pubmed

    • ASO Visual Abstract: Variation in Deescalated Axillary Surgical Practices in Older Women with Early-Stage Breast Cancer. Ann Surg Oncol. 2022 Apr 16. View in: Pubmed

    • Variation in Deescalated Axillary Surgical Practices in Older Women with Early-Stage Breast Cancer. Ann Surg Oncol. 2022 Apr 06. View in: Pubmed

    • Adjuvant Abemaciclib Plus Endocrine Therapy in the Treatment of High-Risk Early Breast Cancer: ASCO Guideline Rapid Recommendation Update Q and A. JCO Oncol Pract. 2022 07; 18(7):516-519. View in: Pubmed

    • The Phase II MutHER Study of Neratinib Alone and in Combination with Fulvestrant in HER2-Mutated, Non-amplified Metastatic Breast Cancer. Clin Cancer Res. 2022 04 01; 28(7):1258-1267. View in: Pubmed

    • Auricular Acupuncture During Chemotherapy Infusion in Breast Cancer Patients: A Feasibility Study. J Integr Complement Med. 2022 May; 28(5):427-435. View in: Pubmed

    • The impact of young age at diagnosis (age <40 years) on prognosis varies by breast cancer subtype: A U.S. SEER database analysis. Breast. 2022 Feb; 61:77-83. View in: Pubmed

    • Abemaciclib With Endocrine Therapy in the Treatment of High-Risk Early Breast Cancer: ASCO Optimal Adjuvant Chemotherapy and Targeted Therapy Guideline Rapid Recommendation Update. J Clin Oncol. 2022 01 20; 40(3):307-309. View in: Pubmed

    • ASO Visual Abstract: Racial and Socioeconomic Disparities in Breast Cancer Outcomes within the AJCC Pathologic Prognostic Staging System. Ann Surg Oncol. 2021 Dec; 28(Suppl 3):585-586. View in: Pubmed

    • Disparities in older adult accrual to cancer trials: Analysis from the alliance for clinical trials in oncology (A151736). J Geriatr Oncol. 2022 01; 13(1):20-26. View in: Pubmed

    • Correction to: Factors associated with late risks of breast cancer-specific mortality in the SEER registry. Breast Cancer Res Treat. 2021 Aug; 189(1):305. View in: Pubmed

    • Racial and Socioeconomic Disparities in Breast Cancer Outcomes within the AJCC Pathologic Prognostic Staging System. Ann Surg Oncol. 2022 Jan; 29(1):686-696. View in: Pubmed

    • A phase II study of efficacy, toxicity, and the potential impact of genomic alterations on response to eribulin mesylate in combination with trastuzumab and pertuzumab in women with human epidermal growth factor receptor 2 (HER2)+ metastatic breast cancer. Breast Cancer Res Treat. 2021 Sep; 189(2):411-423. View in: Pubmed

    • Feasibility of an Online Patient Community to Support Older Women With Newly Diagnosed Breast Cancer. Clin Breast Cancer. 2022 02; 22(2):178-185. View in: Pubmed

    • Risks of subsequent primary cancers among breast cancer survivors according to hormone receptor status. Cancer. 2021 09 15; 127(18):3310-3324. View in: Pubmed

    • Factors associated with late risks of breast cancer-specific mortality in the SEER registry. Breast Cancer Res Treat. 2021 Aug; 189(1):203-212. View in: Pubmed

    • Weathering the Storm: Managing Older Adults With Breast Cancer Amid COVID-19 and Beyond. J Natl Cancer Inst. 2021 04 06; 113(4):355-359. View in: Pubmed

    • Individualizing Surveillance Mammography for Older Patients After Treatment for Early-Stage Breast Cancer: Multidisciplinary Expert Panel and International Society of Geriatric Oncology Consensus Statement. JAMA Oncol. 2021 Apr 01; 7(4):609-615. View in: Pubmed

    • Tumor subtypes and survival in male breast cancer. Breast Cancer Res Treat. 2021 Aug; 188(3):695-702. View in: Pubmed

    • Acceptability of a patient decision aid for women aged 70 and older with stage I, estrogen receptor-positive, HER2-negative breast cancer. J Geriatr Oncol. 2021 06; 12(5):724-730. View in: Pubmed

    • Twenty-year risks of breast cancer-specific mortality for stage III breast cancer in the surveillance, epidemiology, and end results registry. Breast Cancer Res Treat. 2021 Jun; 187(3):843-852. View in: Pubmed

    • Phase I study of JAK1/2 inhibitor ruxolitinib with weekly paclitaxel for the treatment of HER2-negative metastatic breast cancer. Cancer Chemother Pharmacol. 2021 05; 87(5):673-679. View in: Pubmed

    • Development and Validation of a Risk Tool for Predicting Severe Toxicity in Older Adults Receiving Chemotherapy for Early-Stage Breast Cancer. J Clin Oncol. 2021 02 20; 39(6):608-618. View in: Pubmed

    • Phase II trial of carboplatin and bevacizumab in patients with breast cancer brain metastases. Breast Cancer Res. 2020 11 30; 22(1):131. View in: Pubmed

    • Selection of Optimal Adjuvant Chemotherapy and Targeted Therapy for Early Breast Cancer: ASCO Guideline Update. J Clin Oncol. 2021 02 20; 39(6):685-693. View in: Pubmed

    • A dynamic portrait of adverse events for breast cancer patients: results from a phase II clinical trial of eribulin in advanced HER2-negative breast cancer. Breast Cancer Res Treat. 2021 Jan; 185(1):135-144. View in: Pubmed

    • Older adult participation in cancer clinical trials: A systematic review of barriers and interventions. CA Cancer J Clin. 2021 01; 71(1):78-92. View in: Pubmed

    • Oncotype DX testing in node-positive breast cancer strongly impacts chemotherapy use at a comprehensive cancer center. Breast Cancer Res Treat. 2021 Jan; 185(1):215-227. View in: Pubmed

    • Menopausal Hormone Therapy and Long-term Breast Cancer Risk: Further Data From the Women's Health Initiative Trials. JAMA. 2020 07 28; 324(4):347-349. View in: Pubmed

    • Adjuvant Chemotherapy for Older Patients With Breast Cancer: When Is the Pain Worth the Gain? J Natl Cancer Inst. 2020 06 01; 112(6):551-552. View in: Pubmed

    • Translating research into practice: Protocol for a community-engaged, stepped wedge randomized trial to reduce disparities in breast cancer treatment through a regional patient navigation collaborative. Contemp Clin Trials. 2020 06; 93:106007. View in: Pubmed

    • Engaging Patients in Precision Oncology: Development and Usability of a Web-Based Patient-Facing Genomic Sequencing Report. JCO Precis Oncol. 2020; 4. View in: Pubmed

    • HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers. Cancer Discov. 2020 05; 10(5):674-687. View in: Pubmed

    • Follow-up Care for Breast Cancer Survivors. J Natl Cancer Inst. 2020 01 01; 112(1):111-113. View in: Pubmed

    • Identifying ERBB2 Activating Mutations in HER2-Negative Breast Cancer: Clinical Impact of Institute-Wide Genomic Testing and Enrollment in Matched Therapy Trials. JCO Precis Oncol. 2019; 3. View in: Pubmed

    • Acupuncture for Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Survivors: A Randomized Controlled Pilot Trial. Oncologist. 2020 04; 25(4):310-318. View in: Pubmed

    • Acupuncture for Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer Survivors: A Randomized Controlled Pilot Trial. Oncologist. 2019 Oct 14. View in: Pubmed

    • Patterns of Axillary Management in Stages 2 and 3 Hormone Receptor-Positive Breast Cancer by Initial Treatment Approach. Ann Surg Oncol. 2019 Dec; 26(13):4326-4336. View in: Pubmed

    • Standardized activities for lay patient navigators in breast cancer care: Recommendations from a citywide implementation study. Cancer. 2019 12 15; 125(24):4532-4540. View in: Pubmed

    • Pre- and Postoperative Neratinib for HER2-Positive Breast Cancer Brain Metastases: Translational Breast Cancer Research Consortium 022. Clin Breast Cancer. 2020 04; 20(2):145-151.e2. View in: Pubmed

    • 21-Gene Recurrence Score Adds Significant Value for Grade 3 Breast Cancers: Results From a National Cohort. JCO Precis Oncol. 2019; 3. View in: Pubmed

    • Interferon Signaling Is Diminished with Age and Is Associated with Immune Checkpoint Blockade Efficacy in Triple-Negative Breast Cancer. Cancer Discov. 2019 09; 9(9):1208-1227. View in: Pubmed

    • Breast cancer and aging: Standing on the shoulders of a giant. J Geriatr Oncol. 2020 03; 11(2):212-216. View in: Pubmed

    • Arti Hurria, M.D.: A tribute to her shining legacy in the Alliance for Clinical Trials in Oncology. J Geriatr Oncol. 2020 03; 11(2):179-183. View in: Pubmed

    • Developing a patient decision aid for women aged 70 and older with early stage, estrogen receptor positive, HER2 negative, breast cancer. J Geriatr Oncol. 2019 11; 10(6):980-986. View in: Pubmed

    • Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study. Clin Cancer Res. 2019 Sep 01; 25(17):5398-5406. View in: Pubmed

    • Who Are the Patients in Our Clinical Trials for Cancer? J Clin Oncol. 2019 06 20; 37(18):1519-1523. View in: Pubmed

    • Treatment Patterns Among De Novo Metastatic Cancer Patients Who Died Within 1 Month of Diagnosis. JNCI Cancer Spectr. 2019 Jun; 3(2):pkz021. View in: Pubmed

    • Older-Patient-Specific Cancer Trials: A Pooled Analysis of 2,277 Patients (A151715). Oncologist. 2019 06; 24(6):e284-e291. View in: Pubmed

    • TBCRC 022: A Phase II Trial of Neratinib and Capecitabine for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases. J Clin Oncol. 2019 05 01; 37(13):1081-1089. View in: Pubmed

    • Impact of Subtype on Survival of Young Patients With Stage IV Breast Cancer. Clin Breast Cancer. 2019 06; 19(3):200-207.e1. View in: Pubmed

    • Clinical Impact of Second Opinion Radiology Consultation for Patients With Breast Cancer. J Am Coll Radiol. 2019 Jun; 16(6):814-823. View in: Pubmed

    • Examining Associations of Racial Residential Segregation With Patient Knowledge of Breast Cancer and Treatment Receipt. Clin Breast Cancer. 2019 06; 19(3):178-187.e3. View in: Pubmed

    • Age and the Risk of Paclitaxel-Induced Neuropathy in Women with Early-Stage Breast Cancer (Alliance A151411): Results from 1,881 Patients from Cancer and Leukemia Group B (CALGB) 40101. Oncologist. 2019 05; 24(5):617-623. View in: Pubmed

    • Haemophagocytic lymphohistiocytosis complicating pembrolizumab treatment for metastatic breast cancer in a patient with the PRF1A91V gene polymorphism. J Med Genet. 2019 01; 56(1):39-42. View in: Pubmed

    • Treatment Patterns Among Women Diagnosed With Stage I-III Triple-negative Breast Cancer. Am J Clin Oncol. 2018 10; 41(10):997-1007. View in: Pubmed

    • Functional Decline and Resilience in Older Women Receiving Adjuvant Chemotherapy for Breast Cancer. J Am Geriatr Soc. 2019 05; 67(5):920-927. View in: Pubmed

    • Impact of Genomic Assay Testing and Clinical Factors on Chemotherapy Use After Implementation of Standardized Testing Criteria. Oncologist. 2019 05; 24(5):595-602. View in: Pubmed

    • Adherence to Guidelines for Breast Surveillance in Breast Cancer Survivors. J Natl Compr Canc Netw. 2018 05; 16(5):526-534. View in: Pubmed

    • Promoting Accrual of Older Patients with Cancer to Clinical Trials: An Alliance for Clinical Trials in Oncology Member Survey (A171602). Oncologist. 2018 09; 23(9):1016-1023. View in: Pubmed

    • Breast cancer-specific survival by age: Worse outcomes for the oldest patients. Cancer. 2018 05 15; 124(10):2184-2191. View in: Pubmed

    • Morbidity of local therapy for locally advanced metastatic breast cancer: an analysis of the Surveillance, Epidemiology, and End Results (SEER)-Medicare Registry. Breast Cancer Res Treat. 2018 Jun; 169(2):287-293. View in: Pubmed

    • Variation in guideline-concordant care for elderly patients with metastatic breast cancer in the United States. Breast Cancer Res Treat. 2018 Apr; 168(3):727-737. View in: Pubmed

    • Understanding Breast Cancer Knowledge and Barriers to Treatment Adherence: A Qualitative Study Among Breast Cancer Survivors. Biores Open Access. 2017; 6(1):159-168. View in: Pubmed

    • Efficacy and safety in older patient subsets in studies of endocrine monotherapy versus combination therapy in patients with HR+/HER2- advanced breast cancer: a review. Breast Cancer Res Treat. 2018 02; 167(3):607-614. View in: Pubmed

    • Factors That Contributed to Black-White Disparities in Survival Among Nonelderly Women With Breast Cancer Between 2004 and 2013. J Clin Oncol. 2018 01 01; 36(1):14-24. View in: Pubmed

    • Patterns of axillary evaluation in older patients with breast cancer and associations with adjuvant therapy receipt. Breast Cancer Res Treat. 2018 01; 167(2):555-566. View in: Pubmed

    • Breast Cancer Survivorship Care Variations Between Adjuvant Chemotherapy Regimens. Clin Breast Cancer. 2018 08; 18(4):e513-e520. View in: Pubmed

    • Implementation of Surgeon-Initiated Gene Expression Profile Testing (Onco type DX) Among Patients With Early-Stage Breast Cancer to Reduce Delays in Chemotherapy Initiation. J Oncol Pract. 2017 09; 13(9):e815-e820. View in: Pubmed

    • Trends in adjuvant therapies after breast-conserving surgery for hormone receptor-positive ductal carcinoma in situ: findings from the National Cancer Database, 2004-2013. Breast Cancer Res Treat. 2017 Nov; 166(2):583-592. View in: Pubmed

    • Feasibility Assessment of Patient Reporting of Symptomatic Adverse Events in Multicenter Cancer Clinical Trials. JAMA Oncol. 2017 Aug 01; 3(8):1043-1050. View in: Pubmed

    • Use of Surveillance Mammography Among Older Breast Cancer Survivors by Life Expectancy. J Clin Oncol. 2017 Sep 20; 35(27):3123-3130. View in: Pubmed

    • Neratinib Efficacy and Circulating Tumor DNA Detection of HER2 Mutations in HER2 Nonamplified Metastatic Breast Cancer. Clin Cancer Res. 2017 Oct 01; 23(19):5687-5695. View in: Pubmed

    • State Variation in the Receipt of a Contralateral Prophylactic Mastectomy Among Women Who Received a Diagnosis of Invasive Unilateral Early-Stage Breast Cancer in the United States, 2004-2012. JAMA Surg. 2017 07 01; 152(7):648-657. View in: Pubmed

    • Emerging Data and Current Challenges for Young, Old, Obese, or Male Patients with Breast Cancer. Clin Cancer Res. 2017 Jun 01; 23(11):2647-2654. View in: Pubmed

    • Impact of treatment regimen on acute care use during and after adjuvant chemotherapy for early-stage breast cancer. Breast Cancer Res Treat. 2017 Aug; 164(3):515-525. View in: Pubmed

    • Using ePrognosis to estimate 2-year all-cause mortality in older women with breast cancer: Cancer and Leukemia Group B (CALGB) 49907 and 369901 (Alliance A151503). Breast Cancer Res Treat. 2017 Jun; 163(2):391-398. View in: Pubmed

    • Patterns of Utilization of Imaging Studies and Serum Tumor Markers Among Patients With De Novo Metastatic Breast Cancer. J Natl Compr Canc Netw. 2017 03; 15(3):316-324. View in: Pubmed

    • Growing Use of Contralateral Prophylactic Mastectomy Despite no Improvement in Long-term Survival for Invasive Breast Cancer. Ann Surg. 2017 03; 265(3):581-589. View in: Pubmed

    • Surveillance Mammography in Older Patients With Breast Cancer-Can We Ever Stop?: A Review. JAMA Oncol. 2017 Mar 01; 3(3):402-409. View in: Pubmed

    • Prior Authorization for Medications in a Breast Oncology Practice: Navigation of a Complex Process. J Oncol Pract. 2017 04; 13(4):e273-e282. View in: Pubmed

    • Factors Associated with Early Mortality Among Patients with De Novo Metastatic Breast Cancer: A Population-Based Study. Oncologist. 2017 04; 22(4):386-393. View in: Pubmed

    • Persistence of dysphagia and odynophagia after mediastinal radiation and chemotherapy in patients with lung cancer or lymphoma. Dis Esophagus. 2017 02 01; 30(2):1-8. View in: Pubmed

    • Accrual of Older Patients With Breast Cancer to Alliance Systemic Therapy Trials Over Time: Protocol A151527. J Clin Oncol. 2017 Feb; 35(4):421-431. View in: Pubmed

    • Effect of the LIVESTRONG at the YMCA exercise program on physical activity, fitness, quality of life, and fatigue in cancer survivors. Cancer. 2017 Apr 01; 123(7):1249-1258. View in: Pubmed

    • Risk of acute myeloid leukemia and myelodysplastic syndrome among older women receiving anthracycline-based adjuvant chemotherapy for breast cancer on Modern Cooperative Group Trials (Alliance A151511). Breast Cancer Res Treat. 2017 01; 161(2):363-373. View in: Pubmed

    • Treatment of early-stage human epidermal growth factor 2-positive cancers among medicare enrollees: age and race strongly associated with non-use of trastuzumab. Breast Cancer Res Treat. 2016 08; 159(1):151-62. View in: Pubmed

    • Reply to K. Lin et al. J Clin Oncol. 2016 10 01; 34(28):3485-6. View in: Pubmed

    • Learning from social media: utilizing advanced data extraction techniques to understand barriers to breast cancer treatment. Breast Cancer Res Treat. 2016 07; 158(2):395-405. View in: Pubmed

    • Time trends in incidence rates and survival of newly diagnosed stage IV breast cancer by tumor histology: a population-based analysis. Breast Cancer Res Treat. 2016 06; 157(3):587-96. View in: Pubmed

    • Association of Breast Cancer Knowledge With Receipt of Guideline-Recommended Breast Cancer Treatment. J Oncol Pract. 2016 06; 12(6):e613-25. View in: Pubmed

    • Growing Use of Contralateral Prophylactic Mastectomy Despite no Improvement in Long-term Survival for Invasive Breast Cancer. Ann Surg. 2016 Mar 08. View in: Pubmed

    • Patient Prognostic Score and Associations With Survival Improvement Offered by Radiotherapy After Breast-Conserving Surgery for Ductal Carcinoma In Situ: A Population-Based Longitudinal Cohort Study. J Clin Oncol. 2016 Apr 10; 34(11):1190-6. View in: Pubmed

    • Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases. J Clin Oncol. 2016 Mar 20; 34(9):945-52. View in: Pubmed

    • Location Isn't Everything: Proximity, Hospital Characteristics, Choice of Hospital, and Disparities for Breast Cancer Surgery Patients. Health Serv Res. 2016 Aug; 51(4):1561-83. View in: Pubmed

    • Factors associated with radiation therapy incompletion for patients with early-stage breast cancer. Breast Cancer Res Treat. 2016 Jan; 155(1):187-99. View in: Pubmed

    • Temporal Trends in and Factors Associated With Contralateral Prophylactic Mastectomy Among US Men With Breast Cancer. JAMA Surg. 2015 Dec; 150(12):1192-4. View in: Pubmed

    • Treatment of Breast Cancer in the Elderly. Curr Oncol Rep. 2015 Nov; 17(11):51. View in: Pubmed

    • The effect of Paget disease on axillary lymph node metastases and survival in invasive ductal carcinoma. Cancer. 2015 Dec 15; 121(24):4333-40. View in: Pubmed

    • Higher Stage of Disease Is Associated With Bilateral Mastectomy Among Patients With Breast Cancer: A Population-Based Survey. Clin Breast Cancer. 2016 Apr; 16(2):105-12. View in: Pubmed

    • Modern Trends in the Surgical Management of Paget's Disease. Ann Surg Oncol. 2015 Oct; 22(10):3308-16. View in: Pubmed

    • How Do Payers Respond to Regulatory Actions? The Case of Bevacizumab. J Oncol Pract. 2015 Jul; 11(4):313-8. View in: Pubmed

    • Racial differences in outcomes for patients with metastatic breast cancer by disease subtype. Breast Cancer Res Treat. 2015 Jun; 151(3):697-707. View in: Pubmed

    • Black/White Disparities in Receipt of Treatment and Survival Among Men With Early-Stage Breast Cancer. J Clin Oncol. 2015 Jul 20; 33(21):2337-44. View in: Pubmed

    • Racial/Ethnic Differences in Patients' Selection of Surgeons and Hospitals for Breast Cancer Surgery. JAMA Oncol. 2015 May; 1(2):222-30. View in: Pubmed

    • Racial/ethnic disparities in knowledge about one's breast cancer characteristics. Cancer. 2015 Mar 01; 121(5):724-32. View in: Pubmed

    • Patterns of chemotherapy, toxicity, and short-term outcomes for older women receiving adjuvant trastuzumab-based therapy. Breast Cancer Res Treat. 2014 Jun; 145(2):491-501. View in: Pubmed

    • Duration and toxicity of adjuvant trastuzumab in older patients with early-stage breast cancer: a population-based study. J Clin Oncol. 2014 Mar 20; 32(9):927-34. View in: Pubmed

    • A novel community-based delivery model to combat cancer disparities. Healthc (Amst). 2013 Dec; 1(3-4):123-9. View in: Pubmed

    • Using FastTrack to Implement an Academic Medical Center and Community Health Center Collaborative for Cancer Care Delivery. Healthc (Amst). 2013 Dec; 1(3-4):130-135. View in: Pubmed

    • A phase I study of lapatinib with whole brain radiotherapy in patients with Human Epidermal Growth Factor Receptor 2 (HER2)-positive breast cancer brain metastases. Breast Cancer Res Treat. 2013 Nov; 142(2):405-14. View in: Pubmed

    • Managing metastatic human epidermal growth factor receptor 2 (HER2)-positive breast cancer in the older patient. J Geriatr Oncol. 2014 Jan; 5(1):2-7. View in: Pubmed

    • Management of breast cancer in very young women. Breast. 2013 Aug; 22 Suppl 2:S176-9. View in: Pubmed

    • Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907. Breast Cancer Res Treat. 2013 Jun; 139(2):607-16. View in: Pubmed

    • Racial/Ethnic differences in receipt of timely adjuvant therapy for older women with breast cancer: are delays influenced by the hospitals where patients obtain surgical care? Health Serv Res. 2013 Oct; 48(5):1669-83. View in: Pubmed

    • Trends in co-prescribing of antidepressants and tamoxifen among women with breast cancer, 2004-2010. Breast Cancer Res Treat. 2013 Jan; 137(1):285-96. View in: Pubmed

    • Use of adjuvant trastuzumab in women with human epidermal growth factor receptor 2 (HER2)-positive breast cancer by race/ethnicity and education within the National Comprehensive Cancer Network. Cancer. 2013 Feb 15; 119(4):839-46. View in: Pubmed

    • Receipt of locoregional therapy among young women with breast cancer. Breast Cancer Res Treat. 2012 Oct; 135(3):893-906. View in: Pubmed

    • Treatment of Breast Cancer Brain Metastases. Curr Breast Cancer Rep. 2012 Mar 01; 4(1):1-9. View in: Pubmed

    • Adjuvant therapies for very young women with early stage breast cancer. Breast. 2011 Oct; 20 Suppl 3:S146-9. View in: Pubmed

    • A phase II study of sagopilone (ZK 219477; ZK-EPO) in patients with breast cancer and brain metastases. Clin Breast Cancer. 2011 Dec; 11(6):376-83. View in: Pubmed

    • Family cancer history: healthy skepticism required. J Natl Cancer Inst. 2011 May 18; 103(10):776-7. View in: Pubmed

    • The association of race/ethnicity, insurance status, and socioeconomic factors with breast cancer care. Cancer. 2011 Jan 01; 117(1):180-9. View in: Pubmed

    • Adjuvant therapy for postmenopausal women with endocrine-sensitive breast cancer. Breast. 2010 Apr; 19(2):69-75. View in: Pubmed

    • Trends in racial and age disparities in definitive local therapy of early-stage breast cancer. J Clin Oncol. 2009 Feb 10; 27(5):713-9. View in: Pubmed

    • Reducing disparities in breast cancer care: a daunting but essential responsibility. J Natl Cancer Inst. 2008 Dec 03; 100(23):1661-3. View in: Pubmed

    • Timing of postpartum enoxaparin administration and severe postpartum hemorrhage. Blood Coagul Fibrinolysis. 2008 Jan; 19(1):55-9. View in: Pubmed

    • Glioblastoma in a patient with early-stage tonsil cancer. J Clin Oncol. 2007 Jul 01; 25(19):2848-50. View in: Pubmed

    Locations

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    Dana-Farber Cancer Institute

    450 Brookline Avenue Boston, MA 02215
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    Dana-Farber Cancer Institute

    Location Avtar

    Dana-Farber Cancer Institute

    450 Brookline Avenue Boston, MA 02215
    Get Direction
    42.3374, -71.1082

    Ratings and Comments

    Rachel A. Freedman, MD, MPH

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