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Pediatric Wilms' Tumor Clinical Trials
Showing 1-5 of 5 items
1.
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms Tumor
RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, and doxorubicin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving these treatments after surgery may kill any tumor cells that remain after surgery. Sometimes, after surgery, the tumor may not need additional treatment until it progresses. In this case, observation may be sufficient. PURPOSE: This phase III trial is studying vincristine, dactinomycin, and doxorubicin with or without radiation therapy or observation only to see how well they work in treating patients undergoing surgery for newly diagnosed stage I, stage II, or stage III Wilms tumor.
Diagnoses:
Pediatric Wilms' Tumor
Status:
Recruiting
2.
Combination Chemotherapy and Surgery in Treating Young Patients With Wilms Tumor
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving it after surgery may kill any tumor cells that remain after surgery. PURPOSE: This phase III clinical trial is studying how well combination chemotherapy and surgery work in treating young patients with Wilms tumor.
Diagnoses:
Pediatric Wilms' Tumor
Status:
Recruiting
3.
Sorafenib Tosylate in Treating Younger Patients With Relapsed or Refractory Rhabdomyosarcoma, Wilms Tumor, Liver Cancer, or Thyroid Cancer
This phase II trial studies how well sorafenib tosylate works in treating younger patients with relapsed or refractory rhabdomyosarcoma, Wilms tumor, liver cancer, or thyroid cancer. Sorafenib tosylate may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth
Diagnoses:
Pediatric Wilms' Tumor
,
Pediatric Sarcoma
Status:
Recruiting
4.
Ipilimumab in Young Patients With Advanced or Refractory Solid Tumors
RATIONALE: Monoclonal antibodies, such as ipilimumab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. PURPOSE: This phase I trial is studying the side effects and best dose of ipilimumab in treating children, adolescents, and young adults with advanced or refractory solid tumors,
Diagnoses:
Pediatric Hodgkin Lymphoma
,
Pediatric Neuroblastoma
,
Pediatric Sarcoma
,
Pediatric Solid Tumors
,
Pediatric Lymphoma
,
Pediatric Wilms' Tumor
Status:
Recruiting
5.
Study of Kidney Tumors in Young Patients
RATIONALE: Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help the study of cancer in the future. PURPOSE: This laboratory study is looking at kidney tumors in young patients.
Diagnoses:
Pediatric Kidney Tumor
,
Pediatric Wilms' Tumor
Status:
Recruiting
Showing 1-5 of 5 items
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