Brain/Neuro Cancer: Newly Diagnosed Clinical Trials

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  • Combination Chemotherapy With or Without Autologous Stem Cell Transplant in Treating Patients With Central Nervous System B-Cell Lymphoma
  • RATIONALE: Giving chemotherapy before an autologous stem cell transplant stops the growth of cancer cells by stopping them from dividing or killing them. After treatment, stem cells are collected from the patient's blood and stored. More chemotherapy or radiation therapy is given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy. PURPOSE: This randomized phase II trial studies how well combination chemotherapy given together with autologous stem cell transplant works compared to combination chemotherapy alone in treating patients with central nervous system B-cell lymphoma.
  • Diagnoses: Brain/Neuro Cancer: Newly Diagnosed
  • Status: Recruiting
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  • MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors
  • The purpose of this study is to evaluate the safety of MRI-guided focused ultrasound thermal ablation of brain lesions performed through intact human skull using the ExAblate 3000 system. We will collect data to establish the basic safety of this type of treatment as the basis for later studies that will evaluate its clinical efficacy. The hypothesis of the study is to determine if FUS under MRI-guidance and MRI-based thermometry can be safely delivered through an intact human skull with a low risk of transient short-term adverse effects as evaluated during follow-up of up to 3 months and a pre-defined target volume inside the brain lesion can be accurately ablated, as shown on post-treatment MRI.
  • Diagnoses: Brain/Neuro Cancer: Newly Diagnosed
  • Status: Recruiting
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Showing 1-6 of 6 items
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