Integrative Research Centers
Center for Biomedical Imaging in Oncology
Jeffrey T. Yap, PhD, Annick D. Van Den Abbeele, MD, Serena Masciari, MD and Iryna Rastarhuyeva, MD The mission of the Center for Biomedical Imaging in Oncology is
to use state-of-the-art preclinical and clinical imaging in order
to accelerate translational research and develop new diagnostic and
therapeutic strategies for patients with cancer. The Center has two
primary components: the Lurie Family Imaging Center and a clinical
research program.
The Lurie Family Imaging Center is a preclinical imaging
facility equipped with a 7T MRI, microPET/CT, ultrasound,
bioluminescence, and fluorescence imaging instruments, along with
radiochemistry and radiotherapy capabilities. All instruments are
located within a new barrier facility to allow longitudinal and
cross-modality studies. This permits researchers to perform
preclinical cancer biology and drug efficacy studies, incorporating
highly informative noninvasive imaging endpoints.
The Center's clinical research program focuses on the
development and utilization of imaging for the detection of cancer
and evaluation of response to treatment. The program has an Imaging
Design, Evaluation, and Analysis (IDEA) lab, a multidisciplinary
functional imaging laboratory that provides study design, imaging
protocol development, PET/CT scanner evaluation and qualification,
quality control/archival of imaging data, diagnostic review of
images, quantitative image analysis, and scientific interpretation
of final imaging results for numerous institutional, national, and
global multicenter cancer therapeutic trials.
The Center has created a cancer imaging program with seamless
integration between preclinical and clinical imaging and across all
imaging modalities. In light of the expanding role of imaging in
both basic and clinical cancer research, the Center provides a
critical bridge that facilitates bidirectional translation across
the Institute.