Integrative Research Centers
Center for Cancer Computational Biology
John Quackenbush, PhD, and Ursula Matulonis, MD The Center for Cancer Computational Biology provides broad-based
support for the analysis and interpretation of genomic and other
large-scale data and, by doing so, furthers basic, clinical, and
translational research. The Center also conducts research focused
on genomic and computational biology approaches that open new ways
of understanding cancer.
The Center has developed a unique bioinformatics and
computational biology consulting platform that provides
state-of-the-art assistance in the collection, management,
analysis, and interpretation of large-scale data, with a focus on
data generated using "omic" technologies. To accomplish this,
bioinformatics consultants and staff work closely with
investigators in designing experiments and in analyzing and
interpreting the data. They assist investigators with their
research and provide training in various analytical methods, as
well as the use of software tools.
Recognizing that many emerging problems in genomic data analysis
require the development of new methods, the Center also maintains
an active research program. Focusing on integrative approaches to
the analysis of genomic data, it is proactively generating data
using emerging technologies. It is also developing methods and
software tools that bring together information from a variety of
sources, including publicly available data, to better understand
the complexities of biological systems. All software and tools
developed through the Center are available to the research
community as a resource to accelerate research at Dana-Farber, and
beyond.