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Integrative Therapies

Milk thistle (Silybum marianum)

One function of the liver is to detoxify and remove toxins, including heavy metals and chemotherapy, from the body. Milk thistle is a liver protective. It is an antioxidant that helps repair damaged liver cells.

What is involved

Silymarin is the ingredient in milk thistle that may have the ability to protect the liver. Taken orally by mouth it may be in tablet, liquid or whole seed form. The liquid extract (tincture) is not recommended for severe liver disease (cirrhosis, yellow jaundice or bleeding disorders).

What has been proven

Studies have shown evidence that silymarin acts almost solely on the liver and kidney. The antioxidant properties in silymarin are believed to be the protective factors

(Caution: Because the Food and Drug Administration (FDA) does not consider these substances to be medications, the contents are not subject to the same manufacturing standards. You should be aware that the contents may vary from product to product.)

What does it cost?

Cost varies. A number of pharmacies and health food stores offer affordable products. There are a wide variety of preparations available. Your healthcare provider can help you with this and should/must be informed if you are taking supplements.

Possible side effects

Human studies performed have shown few side effects if milk thistle is taken according to instruction. You may have a brief stomach or intestinal upset (diarrhea) or mild allergic reactions, but this is rare.

Special considerations

  • If you are diabetic, you should check your blood sugar more frequently. Milk Thistle may require a change in your antidiabetic medication.
  • It is very important to take this herb as recommended.
  • It is essential to discuss this treatment with your physician or nurse.
  • It is best to take before bedtime.

Ref: The Review of Natural Products Facts and Comparisons. Copyright 1996.

For additional information and services offered through the Zakim Center for Integrated Therapies at Dana-Farber, please call (617) 632-5570.

By making this information available, neither the Patient Family Education council nor Dana-Farber Cancer Institute makes any recommendations, promises, or guarantees the effectiveness of this complementary therapy. For any serious condition please contact your doctor before trying any new therapy. If you do decide to try this modality of therapy, please inform your doctor or nurse so all practitioners can work together to help you in the healing process.