Lymphoma is not just one disease but a group of cancers that originate in cells of the immune system, called lymphocytes. Lymphomas often begin in lymph nodes, but may arise in any organ of the body, including kidneys, liver, spleen, bone, bone marrow, skin, and brain.
There are two main types of lymphoma:
- Hodgkin lymphoma is marked by the presence of Reed-Sternberg cells (mature B cells that are unusually large.
- Non-Hodgkin lymphomas do not have the Reed-Sternberg cells. There are many sub-types of non-Hodgkin lymphoma, including:
Lymphomas occur in both children and adults. However the particular types of lymphoma that are most common in children are different from those in adults, and treatment recommendations and outcomes are different for children than for adults.
The prognosis for children with lymphoma is generally good. More than 80 percent of children and adolescents with non-Hodgkin lymphoma are cured, and children with Hodgkin lymphoma have survival rates between 90 and 95 percent.
Lymphoma treatment at Dana-Farber/Boston Children's
Children with lymphoma are treated at Dana-Farber/Boston Children's through the Lymphoma Program in our Hematologic Malignancies Center. One of the top pediatric cancer centers worldwide, Dana-Farber/Boston Children’s combines the expertise of a premier cancer center – Dana-Farber Cancer Institute – and a world-class children’s hospital – Boston Children’s Hospital – to provide internationally-renowned care for children with cancers of the blood and immune system.