Danielle N. Margalit, MD, MPH

Neoadjuvant chemotherapy for advanced oral cavity cancer. CA Cancer J Clin. 2024 Feb 08. View in: Pubmed

Imaging and Biomarker Surveillance for Head and Neck Squamous Cell Carcinoma: A Systematic Review and AUC Document. Int J Radiat Oncol Biol Phys. 2023 Dec 31. View in: Pubmed

Outcomes of palliative radiation therapy for cutaneous squamous cell carcinoma: A retrospective cohort study. JAAD Int. 2024 Mar; 14:26-28. View in: Pubmed

Definitive radiation therapy for inoperable stage III/IV cutaneous squamous cell carcinoma: A single-institution retrospective cohort study. J Am Acad Dermatol. 2024 Jan; 90(1):187-189. View in: Pubmed

Development and Validation of an Automated Image-Based Deep Learning Platform for Sarcopenia Assessment in Head and Neck Cancer. JAMA Netw Open. 2023 08 01; 6(8):e2328280. View in: Pubmed

The Interplay Between Radiation Dose, Volume, and Systemic Therapy. Int J Radiat Oncol Biol Phys. 2023 Aug 01; 116(5):967-971. View in: Pubmed

Screening for extranodal extension in HPV-associated oropharyngeal carcinoma: evaluation of a CT-based deep learning algorithm in patient data from a multicentre, randomised de-escalation trial. Lancet Digit Health. 2023 06; 5(6):e360-e369. View in: Pubmed

Fully-automated sarcopenia assessment in head and neck cancer: development and external validation of a deep learning pipeline. medRxiv. 2023 Mar 06. View in: Pubmed

Association of Pretreatment Circulating Tumor Tissue-Modified Viral HPV DNA With Clinicopathologic Factors in HPV-Positive Oropharyngeal Cancer. JAMA Otolaryngol Head Neck Surg. 2022 12 01; 148(12):1120-1130. View in: Pubmed

Negative and positive personification of multiple sclerosis: Role in psychological adaptation. J Psychosom Res. 2023 01; 164:111078. View in: Pubmed

Interventions for head and neck cancer survivors: Systematic review. Head Neck. 2022 11; 44(11):2579-2599. View in: Pubmed

A Bit More Here and a Little Less There: The Trials (and Tribulations) of Adjuvant and Neoadjuvant Head and Neck Studies in 2021. Int J Radiat Oncol Biol Phys. 2022 06 01; 113(2):243-251. View in: Pubmed

Characterization of clinical outcomes after shorter course hypofractionated and standard-course radiotherapy for stage I-III curatively-treated Merkel cell carcinoma. Radiother Oncol. 2022 08; 173:32-40. View in: Pubmed

Retreatment of Recurrent or Second Primary Head and Neck Cancer After Prior Radiation: Executive Summary of the American Radium Society Appropriate Use Criteria. Int J Radiat Oncol Biol Phys. 2022 07 15; 113(4):759-786. View in: Pubmed

Association between radiation dose to organs at risk and acute patient reported outcome during radiation treatment for head and neck cancers. Head Neck. 2022 06; 44(6):1442-1452. View in: Pubmed

Adjuvant radiation following clear margin resection of high T-stage cutaneous squamous cell carcinoma halves the risk of local and locoregional recurrence: A dual-center retrospective study. J Am Acad Dermatol. 2022 07; 87(1):87-94. View in: Pubmed

Oligometastatic adenoid cystic carcinoma: Correlating tumor burden and time to treatment with outcomes. Head Neck. 2022 03; 44(3):722-734. View in: Pubmed

Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res. 2022 02 01; 28(3):468-478. View in: Pubmed

Something for Everyone From Low-Risk to High-Risk: 5 Recent Studies to Improve Treatment and Surveillance for All Patients With Squamous Cell Carcinoma of the Head and Neck. Int J Radiat Oncol Biol Phys. 2021 09 01; 111(1):1-8. View in: Pubmed

Epidemiologic distinctions between base of tongue and tonsil oropharyngeal carcinomas. Head Neck. 2021 10; 43(10):3076-3085. View in: Pubmed

Head and Neck Cancer Clinical Research on ClinicalTrials.gov: An Opportunity for Radiation Oncologists. Adv Radiat Oncol. 2021 May-Jun; 6(3):100608. View in: Pubmed

Association between treatment center experience and survival after diagnosis of stage I to III Merkel cell carcinoma treated with surgery with or without postoperative radiation therapy. J Am Acad Dermatol. 2021 Mar; 84(3):875-877. View in: Pubmed

Hospitalization rates and 30-day all-cause mortality among head and neck cancer patients and survivors with COVID-19. Oral Oncol. 2021 01; 112:105087. View in: Pubmed

Systematic review of postoperative therapy for resected squamous cell carcinoma of the head and neck: Executive summary of the American Radium Society appropriate use criteria. Head Neck. 2021 01; 43(1):367-391. View in: Pubmed

Ipsilateral radiation for squamous cell carcinoma of the tonsil: American Radium Society appropriate use criteria executive summary. Head Neck. 2021 01; 43(1):392-406. View in: Pubmed

Neoadjuvant Nivolumab or Nivolumab Plus Ipilimumab in Untreated Oral Cavity Squamous Cell Carcinoma: A Phase 2 Open-Label Randomized Clinical Trial. JAMA Oncol. 2020 10 01; 6(10):1563-1570. View in: Pubmed

Patient reported outcomes in patients with head and neck cancer treated with concurrent chemoradiation with weekly versus bolus cisplatin. Head Neck. 2020 12; 42(12):3670-3677. View in: Pubmed

A Randomized Phase 2 Study of Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma. Int J Radiat Oncol Biol Phys. 2021 01 01; 109(1):134-144. View in: Pubmed

Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: An ASTRO-ESTRO consensus statement. Radiother Oncol. 2020 10; 151:314-321. View in: Pubmed

Osteonecrosis of the jaw and dental extractions: A single-center experience. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Nov; 130(5):515-521. View in: Pubmed

Follow-Up and Management of Patients With Head and Neck Cancer During the 2019 Novel Coronavirus (SARS-CoV-2) Disease Pandemic. Adv Radiat Oncol. 2020 Jul-Aug; 5(4):631-636. View in: Pubmed

The Benefits of Adjuvant Trastuzumab for HER-2-Positive Salivary Gland Cancers. Oncologist. 2020 07; 25(7):598-608. View in: Pubmed

Practice Recommendations for Risk-Adapted Head and Neck Cancer Radiation Therapy During the COVID-19 Pandemic: An ASTRO-ESTRO Consensus Statement. Int J Radiat Oncol Biol Phys. 2020 07 15; 107(4):618-627. View in: Pubmed

Long-term outcomes and clinicogenomic correlates in recurrent, metastatic adenoid cystic carcinoma. Oral Oncol. 2020 07; 106:104690. View in: Pubmed

Chemotherapy after immune checkpoint blockade in patients with recurrent, metastatic squamous cell carcinoma of the head and neck. Oral Oncol. 2020 06; 105:104676. View in: Pubmed

Four Influential Clinical Trials in Human Papilloma Virus-Associated Oropharynx Cancer. Int J Radiat Oncol Biol Phys. 2020 04 01; 106(5):893-899. View in: Pubmed

Combined interstitial and surface high-dose-rate brachytherapy treatment of squamous cell carcinoma of the hand. J Contemp Brachytherapy. 2020 Feb; 12(1):48-52. View in: Pubmed

Short-term mortality risks among patients with oropharynx cancer by human papillomavirus status. Cancer. 2020 04 01; 126(7):1424-1433. View in: Pubmed

Incidence and Demographic Burden of HPV-Associated Oropharyngeal Head and Neck Cancers in the United States. Cancer Epidemiol Biomarkers Prev. 2019 10; 28(10):1660-1667. View in: Pubmed

De-Escalation Strategies in HPV-Associated Oropharynx Cancer-Are we Putting the Cart Before the Horse? Int J Radiat Oncol Biol Phys. 2019 07 15; 104(4):705-709. View in: Pubmed

Modeling the Potential Benefits of Proton Therapy for Patients With Oropharyngeal Head and Neck Cancer. Int J Radiat Oncol Biol Phys. 2019 07 01; 104(3):563-566. View in: Pubmed

A Phase 1 Study of Afatinib in Combination with Postoperative Radiation Therapy with and Without Weekly Docetaxel in Intermediate- and High-Risk Patients with Resected Squamous Cell Carcinoma of the Head and Neck. Int J Radiat Oncol Biol Phys. 2019 09 01; 105(1):132-139. View in: Pubmed

Everolimus in Anaplastic Thyroid Cancer: A Case Series. Front Oncol. 2019; 9:106. View in: Pubmed

Outcomes following radiation for cutaneous squamous cell carcinoma of the head and neck: Associations between immune suppression and recurrence. Head Neck. 2019 07; 41(7):2111-2115. View in: Pubmed

IMRT-based treatment of unknown primary malignancy of the head and neck: Outcomes and improved toxicity with decreased mucosal dose and larynx sparing. Head Neck. 2019 04; 41(4):959-966. View in: Pubmed

Evaluation of a community-based dental screening program prior to radiotherapy for head and neck cancer: a single-center experience. Support Care Cancer. 2019 Sep; 27(9):3331-3336. View in: Pubmed

Radiation dose enhancement associated with contemporary dental materials. J Prosthet Dent. 2019 Apr; 121(4):703-707. View in: Pubmed

Two Sides of the Same Coin: Head and Neck Cancer Treatment De-Intensification and Intensification with Induction Chemotherapy. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):1-4. View in: Pubmed

Evaluating the PD-1 Axis and Immune Effector Cell Infiltration in Oropharyngeal Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):137-145. View in: Pubmed

Funding Support and Principal Investigator Leadership of Oncology Clinical Trials Using Radiation Therapy. Int J Radiat Oncol Biol Phys. 2018 09 01; 102(1):34-43. View in: Pubmed

Treatment-refractory ALK-positive inflammatory myofibroblastic tumour of the oral cavity. BMJ Case Rep. 2018 Apr 11; 2018. View in: Pubmed

Reirradiation for Head and Neck Cancer: The Who and the How. Int J Radiat Oncol Biol Phys. 2018 03 01; 100(3):618-620. View in: Pubmed

Palliative Head and Neck Cancer Treatment for Asymptomatic Disease. Otolaryngol Head Neck Surg. 2018 07; 159(1):25-28. View in: Pubmed

The Touchy Topic of the Touch Cell: A Case of Merkel Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2018 01 01; 100(1):12-13. View in: Pubmed

The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana-Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline. Oncologist. 2017 11; 22(11):1413. View in: Pubmed

Patient-oriented toxicity endpoints after head and neck reirradiation with intensity modulated radiation therapy. Oral Oncol. 2017 10; 73:160-165. View in: Pubmed

Comparative Analysis of MicroRNA Expression among Benign and Malignant Tongue Tissue and Plasma of Patients with Tongue Cancer. Front Oncol. 2017; 7:191. View in: Pubmed

Prospective analysis of radiation oncology image and plan-driven peer review for head and neck cancer. Head Neck. 2017 08; 39(8):1603-1608. View in: Pubmed

The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana-Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline. Oncologist. 2017 03; 22(3):343-350. View in: Pubmed

Salivary and serum HPV antibody levels before and after definitive treatment in patients with oropharyngeal squamous cell carcinoma. Cancer Biomark. 2017; 19(2):129-136. View in: Pubmed

A comparative study of standard intensity-modulated radiotherapy and RapidArc planning techniques for ipsilateral and bilateral head and neck irradiation. Med Dosim. 2017 Spring; 42(1):31-36. View in: Pubmed

Merkel Cell Carcinoma: A Population Analysis on Survival. J Natl Compr Canc Netw. 2016 10; 14(10):1247-1257. View in: Pubmed

Patterns of failure after reirradiation with intensity-modulated radiation therapy and the competing risk of out-of-field recurrences. Oral Oncol. 2016 10; 61:19-26. View in: Pubmed

Definitive chemoradiation alters the immunologic landscape and immune checkpoints in head and neck cancer. Br J Cancer. 2016 07 12; 115(2):252-60. View in: Pubmed

Effects of definitive chemoradiation on circulating immunologic angiogenic cytokines in head and neck cancer patients. J Immunother Cancer. 2016; 4:32. View in: Pubmed

SU-F-T-426: Measurement of Dose Enhancement Due to Backscatter From Modern Dental Materials. Med Phys. 2016 Jun; 43(6):3561. View in: Pubmed

Population-based validation of the recursive partitioning analysis-based staging system for oropharyngeal cancer. Head Neck. 2016 10; 38(10):1530-8. View in: Pubmed

Synchronous squamous cell carcinoma and diffuse large B-cell lymphoma of the head and neck: the odd couple. BJR Case Rep. 2016; 2(1):20150271. View in: Pubmed

Incorporation of Next-Generation Sequencing into Routine Clinical Care to Direct Treatment of Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2016 06 15; 22(12):2939-49. View in: Pubmed

Radiation Oncology--New Approaches in Squamous Cell Cancer of the Head and Neck. Hematol Oncol Clin North Am. 2015 Dec; 29(6):1093-106. View in: Pubmed

Changing prognostic significance of tumor stage and nodal stage in patients with squamous cell carcinoma of the oropharynx in the human papillomavirus era. Cancer. 2015 Aug 01; 121(15):2594-602. View in: Pubmed

Ensuring head and neck oncology patients receive recommended pretreatment dental evaluations. J Oncol Pract. 2015 Mar; 11(2):151-4. View in: Pubmed

GermLine Variation in Superoxide Dismutase-2 (SOD2) and Survival Outcomes After Radiation Therapy for Prostate Cancer: Results of a Test and Validation Set Analysis. Clin Genitourin Cancer. 2015 Aug; 13(4):370-377.e1. View in: Pubmed

SU-E-T-581: A Comparative Study of Standard IMRT and VMAT Planning Techniques for Unilateral and Bilateral Head & Neck Irradiation. Med Phys. 2014 Jun; 41(6):361. View in: Pubmed

Associations between single nucleotide polymorphisms (SNPs) in inflammation-related genes and quality of life after radiation therapy (RT) for prostate cancer. J Clin Oncol. 2013 Feb 20; 31(6_suppl):2. View in: Pubmed

A single nucleotide polymorphism in inflammatory gene RNASEL predicts outcome after radiation therapy for localized prostate cancer. Clin Cancer Res. 2013 Mar 15; 19(6):1612-9. View in: Pubmed

Microinvasive breast cancer: ER, PR, and HER-2/neu status and clinical outcomes after breast-conserving therapy or mastectomy. Ann Surg Oncol. 2013 Mar; 20(3):811-8. View in: Pubmed

Active tobacco smoking and distant metastasis in patients with oropharyngeal cancer. Int J Radiat Oncol Biol Phys. 2012 Sep 01; 84(1):183-8. View in: Pubmed

Beta-carotene antioxidant use during radiation therapy and prostate cancer outcome in the Physicians' Health Study. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):28-32. View in: Pubmed

Technological advancements and error rates in radiation therapy delivery. Int J Radiat Oncol Biol Phys. 2011 Nov 15; 81(4):e673-9. View in: Pubmed

Tolerability of combined modality therapy for rectal cancer in elderly patients aged 75 years and older. Int J Radiat Oncol Biol Phys. 2011 Dec 01; 81(5):e735-41. View in: Pubmed

Isolation and characterization of conditional alleles of the yeast SIR2 gene. J Mol Biol. 2007 Apr 13; 367(5):1246-57. View in: Pubmed

Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality. Proc Natl Acad Sci U S A. 2004 Aug 10; 101(32):11821-6. View in: Pubmed