G. Mike Makrigiorgos, PhD

G. Mike Makrigiorgos, PhD

Researcher

Contact Information

Office Phone Number

(617) 525-7122

Fax

(617) 582-6037

Biography

G. Mike Makrigiorgos, PhD

Dr Makrigiorgos graduated from the University of Athens, Greece in 1981 (BSc) and from the University of Leeds, UK in 1984 (Ph.D). Following a postdoctoral fellowship in radiation biology at Harvard Medical School he joined the faculty of the Joint Center for Radiation Therapy, Harvard Medical School. He is currently the Director of the Medical Physics and Biophysics Division of the joint department of radiation therapy at Dana Farber Cancer Institute and Brigham and Women’s Hospital and a Professor at Harvard Medical School. He is as ABR-certified radiation oncology physicist, an NIH-funded principal investigator of a DNA technology laboratory and director of a radiation pre-clinical facility. He is on the Editorial Board of Clinical Chemistry and has published over 150 articles, reviews and book chapters.

Researcher

Physician

Professor of Radiation Oncology, Dana-Farber Cancer Institute and Harvard Medical School
Director of the Medical Physics and Biophysics Division, Department of Radiation Oncology, Dana-Farber Cancer Institute and Brigham and Women's Hospital

Centers/Programs

Clinical Interests

Cancer genomics, Liquid biopsies

Board Certification

  • American Board of Medical Physics
  • American Board of Radiology Equivalency

Research

    Technology development for liquid biopsy and mutational profiling of cancer

    We are developing technologies for molecular profiling of human tumors. In particular, we have devised technologies for detecting low-level DNA mutations, micro-satellite instability and methylation in clinical samples. We are using these new technologies to improve detection of cancer DNA biomarkers in human blood (‘liquid biopsies’), for the purpose of early detection of cancer, and for monitoring the progress of radio/chemotherapy or for detection of minimal residual disease. Ongoing clinical studies are evaluating these biomarkers in radiation oncology and medical oncology patients.

    Research Departments

    Locations

    Location Avtar

    Brigham and Women's Hospital

    75 Francis Street Radiation Therapy LL2 Boston, MA 02215
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    Brigham and Women's Hospital

    Location Avtar

    Brigham and Women's Hospital

    75 Francis Street Radiation Therapy LL2 Boston, MA 02215
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    42.3362, -71.1067

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