Paul L. Nguyen, MD, MBA

Paul L. Nguyen, MD, MBA

Radiation Oncology

Contact Information

Office Phone Number

617-732-8821

Fax

617-394-2668

Appointments

617-632-2682 (new)

Biography

Paul L. Nguyen, MD, MBA

Dr. Paul Nguyen is an internationally-recognized expert in prostate cancer clinical care and research.  He has published over 350 original research articles and has national leadership as Co-Chair of the National Cancer Institute's GU Steering Committee, Chair of the ARS/ACR Appropriateness Criteria Committee for Prostate Cancer, and Chair of the ASTRO Annual Refresher Course.  He is the Principal Investigator of the multi-center randomized FORMULA-509 trial and the national NRG Oncology GU-009/PREDICT-RT trial, and Co-Chair of the international randomized ENZARAD trial.  His research is supported by an NIH R-01 grant.  He serves as the DF/BWCC Genitourinary Clinical Center Director for Radiation Oncology, Vice-Chair for Clinical Research in the Department of Radiation Oncology, Professor at Harvard Medical School, and Baldwin-Politi Distinguished Chair in Oncology at Brigham and Women's Hospital where he is also associate director of the Harvard Radiation Oncology Program residency.  He received his AB from Harvard College, MD from Harvard Medical School, MBA from the MIT Sloan School of Management, and completed his residency at the Harvard Radiation Oncology Program where he served as chief resident.

Researcher

Physician

Senior Physician
Professor of Radiation Oncology, Harvard Medical School
Director, Genitourinary Radiation Oncology

Centers/Programs

Bladder Cancer

Clinical Interests

Genitourinary malignancies, Prostate brachytherapy, Prostate cancer

Board Certification

  • Radiation Oncology

Residency

  • Harvard Radiation Oncology Program

Medical School

  • Harvard Medical School

Research

    Dr. Nguyen’s primary research expertise is the optimal use of systemic therapy with radiation for high-risk prostate cancer, side effects of androgen-deprivation therapy, and the genetic and molecular markers to optimize risk stratification and personalization of treatment for men with prostate cancer.  In addition he has published extensively in health services research and racial disparities in prostate cancer treatment and outcome.

    Publications

      • Secondary analysis of late major gastrointestinal and genitourinary toxicities in unfavorable-risk prostate cancer patients receiving docetaxel: Insights from a randomized trial. Cancer. 2024 Mar 01. View in: Pubmed

      • Trends in Utilization and Medicare Spending on Short-Course Radiation Therapy for Breast and Prostate Cancer: An Episode-Based Analysis From 2015 to 2019. Int J Radiat Oncol Biol Phys. 2023 Dec 08. View in: Pubmed

      • Major adverse cardiovascular events of enzalutamide versus abiraterone in prostate cancer: a retrospective cohort study. Prostate Cancer Prostatic Dis. 2023 Dec 05. View in: Pubmed

      • The Efficacy and Safety of Metastasis-directed Therapy in Patients with Prostate Cancer: A Systematic Review and Meta-analysis of Prospective Studies. Eur Urol. 2024 Feb; 85(2):125-138. View in: Pubmed

      • Burden of prostate cancer in the Middle East: A comparative analysis based on global cancer observatory data. Cancer Med. 2023 12; 12(23):21419-21425. View in: Pubmed

      • MR-guided prostate SBRT in prostate cancer patients with low-volume metastatic disease. World J Urol. 2023 Dec; 41(12):3889-3894. View in: Pubmed

      • Modifiable risk factors for subsequent lethal prostate cancer among men with an initially negative prostate biopsy. Br J Cancer. 2023 12; 129(12):1988-2002. View in: Pubmed

      • Leveraging national and global political determinants of health to promote equity in cancer care. J Natl Cancer Inst. 2023 10 09; 115(10):1157-1163. View in: Pubmed

      • Observer preference of artificial intelligence-generated versus clinical prostate contours for ultrasound-based high dose rate brachytherapy. Med Phys. 2023 Oct; 50(10):5935-5943. View in: Pubmed

      • The Clinical Significance of Aspergillus Detected in Lower-Respiratory-Tract Samples of Critically Ill COVID-19-Positive Patients. Adv Respir Med. 2023 Sep 02; 91(5):337-349. View in: Pubmed

      • Assessing the Feasibility of Using Artificial Intelligence-Segmented Dominant Intraprostatic Lesion for Focal Intraprostatic Boost With External Beam Radiation Therapy. Int J Radiat Oncol Biol Phys. 2024 Jan 01; 118(1):74-84. View in: Pubmed

      • Acute toxicity comparison of magnetic resonance-guided adaptive versus fiducial or computed tomography-guided non-adaptive prostate stereotactic body radiotherapy: A systematic review and meta-analysis. Cancer. 2023 10 01; 129(19):3044-3052. View in: Pubmed

      • Mucosal CCL28 Chemokine Improves Protection against Genital Herpes through Mobilization of Antiviral Effector Memory CCR10+CD44+ CD62L-CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells into the Infected Vaginal Mucosa. J Immunol. 2023 07 01; 211(1):118-129. View in: Pubmed

      • Artificial Intelligence Predictive Model for Hormone Therapy Use in Prostate Cancer. NEJM Evid. 2023 Aug; 2(8):EVIDoa2300023. View in: Pubmed

      • ASO Visual Abstract: Colon Cancer Disparities in Stage at Presentation and Time to Surgery for Asian Americans, Native Hawaiians, and Pacific Islanders: A Study with Disaggregated Ethnic Groups. Ann Surg Oncol. 2023 Jun 17. View in: Pubmed

      • Disparities in Diagnosis, Treatment Access, and Time to Treatment Among Hispanic Men With Metastatic Prostate Cancer. JCO Oncol Pract. 2023 08; 19(8):645-653. View in: Pubmed

      • Genetic and Genomic Testing for Prostate Cancer: Beyond DNA Repair. Am Soc Clin Oncol Educ Book. 2023 May; 43:e390384. View in: Pubmed

      • ASO Author Reflections: Colon Cancer Disparities in Stage at Presentation and Time to Surgery for Asian Americans, Native Hawaiians, and Pacific Islanders. Ann Surg Oncol. 2023 09; 30(9):5506-5508. View in: Pubmed

      • Artificial Intelligence Predictive Model for Hormone Therapy Use in Prostate Cancer. Res Sq. 2023 Apr 21. View in: Pubmed

      • Colon Cancer Disparities in Stage at Presentation and Time to Surgery for Asian Americans, Native Hawaiians, and Pacific Islanders: A Study with Disaggregated Ethnic Groups. Ann Surg Oncol. 2023 Sep; 30(9):5495-5505. View in: Pubmed

      • Determinants of widespread metastases and of metastatic tropism in patients with prostate cancer: A genomic analysis of primary and metastatic tumors. Urol Oncol. 2023 05; 41(5):253.e21-253.e26. View in: Pubmed

      • Management of patients with advanced prostate cancer-metastatic and/or castration-resistant prostate cancer: Report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022. Eur J Cancer. 2023 05; 185:178-215. View in: Pubmed

      • Transcriptomic Heterogeneity in High-risk Prostate Cancer and Implications for Extraprostatic Disease at Presentation on Prostate-specific Membrane Antigen Positron Emission Tomography. Eur Urol Oncol. 2023 04; 6(2):224-227. View in: Pubmed

      • Uncontrolled Cardiovascular Risk Factors in Prostate Cancer Patients: Are We Leaving Too Much on the Table? JACC CardioOncol. 2023 Feb; 5(1):82-84. View in: Pubmed

      • Gaining metabolic insight in older men undergoing androgen deprivation therapy for prostate cancer (the ADT & Metabolism Study): Protocol of a longitudinal, observational, cohort study. PLoS One. 2023; 18(2):e0281508. View in: Pubmed

      • Analysis of a Biopsy-Based Genomic Classifier in High-Risk Prostate Cancer: Meta-Analysis of the NRG Oncology/Radiation Therapy Oncology Group 9202, 9413, and 9902 Phase 3 Randomized Trials. Int J Radiat Oncol Biol Phys. 2023 07 01; 116(3):521-529. View in: Pubmed

      • Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022. Eur Urol. 2023 03; 83(3):267-293. View in: Pubmed

      • Shorter Radiation Regimens and Treatment Noncompletion Among Patients With Breast and Prostate Cancer in the United States: An Analysis of Racial Disparities in Access and Quality. JCO Oncol Pract. 2023 02; 19(2):e197-e212. View in: Pubmed

      • Distinct Profiles of DNA Repair Activity Define Favorable-risk Prostate Cancer Subtypes With Divergent Outcome. Clin Genitourin Cancer. 2023 02; 21(1):76-83. View in: Pubmed

      • Genomic alterations predictive of poor clinical outcomes in pan-cancer. Oncotarget. 2022; 13:1069-1077. View in: Pubmed

      • The Increasing Importance of Rigorous Real-World Evidence. JNCI Cancer Spectr. 2022 Aug 10. View in: Pubmed

      • Shared burden: the association between cancer diagnosis, financial toxicity, and healthcare cost-related coping mechanisms by family members of non-elderly patients in the USA. Support Care Cancer. 2022 Nov; 30(11):8905-8917. View in: Pubmed

      • The Influence of the Pretreatment Immune State on Response to Radiation Therapy in High-Risk Prostate Cancer: A Validation Study From NRG/RTOG 0521. Int J Radiat Oncol Biol Phys. 2022 10 01; 114(2):266-274. View in: Pubmed

      • Second malignancy probabilities in patients with prostate cancer treated with whole pelvis radiation therapy versus prostate only radiation therapy. Prostate. 2022 08; 82(11):1098-1106. View in: Pubmed

      • Corrigendum to definitive and sustained increase in prostate cancer metastases in the United States. Urol Oncol. 2022 Jul; 40(7):354. View in: Pubmed

      • Localized prostate cancer disparities in risk group at presentation and access to treatment for Hispanic men. Prostate Cancer Prostatic Dis. 2023 06; 26(2):309-316. View in: Pubmed

      • Magnetic Resonance-Guided Prostate Stereotactic Body Radiation Therapy With Daily Online Plan Adaptation: Results of a Prospective Phase 1 Trial and Supplemental Cohort. Adv Radiat Oncol. 2022 Sep-Oct; 7(5):100934. View in: Pubmed

      • Racial disparities in treatment delay among younger men with prostate cancer. Prostate Cancer Prostatic Dis. 2022 09; 25(3):590-592. View in: Pubmed

      • Comparison of Response to Definitive Radiotherapy for Localized Prostate Cancer in Black and White Men: A Meta-analysis. JAMA Netw Open. 2021 12 01; 4(12):e2139769. View in: Pubmed

      • Prostate Cancer Disparities in Risk Group at Presentation and Access to Treatment for Asian Americans, Native Hawaiians, and Pacific Islanders: A Study With Disaggregated Ethnic Groups. JCO Oncol Pract. 2022 01; 18(1):e204-e218. View in: Pubmed

      • Radiation Dose to the Intraprostatic Urethra Correlates Strongly With Urinary Toxicity After Prostate Stereotactic Body Radiation Therapy: A Combined Analysis of 23 Prospective Clinical Trials. Int J Radiat Oncol Biol Phys. 2022 01 01; 112(1):75-82. View in: Pubmed

      • The Clinical Cell-Cycle Risk (CCR) Score Is Associated With Metastasis After Radiation Therapy and Provides Guidance on When to Forgo Combined Androgen Deprivation Therapy With Dose-Escalated Radiation. Int J Radiat Oncol Biol Phys. 2022 05 01; 113(1):66-76. View in: Pubmed

      • Exercise: A Treatment That Should Be Prescribed With Radiation Therapy. Int J Radiat Oncol Biol Phys. 2022 01 01; 112(1):96-98. View in: Pubmed

      • Trends in Incidence, and Mortality of Acute Exacerbation of Chronic Obstructive Pulmonary Disease in the United States Emergency Department (2010-2018). COPD. 2021 10; 18(5):567-575. View in: Pubmed

      • Boosting the Abscopal Effect Using Immunogenic Biomaterials With Varying Radiation Therapy Field Sizes. Int J Radiat Oncol Biol Phys. 2022 02 01; 112(2):475-486. View in: Pubmed

      • High-flow nasal cannula therapy in a predominantly African American population with COVID-19 associated acute respiratory failure. BMJ Open Respir Res. 2021 09; 8(1). View in: Pubmed

      • Novel genomic signature predictive of response to immune checkpoint blockade: A pan-cancer analysis from project Genomics Evidence Neo-plasia Information Exchange (GENIE). Cancer Genet. 2021 11; 258-259:61-68. View in: Pubmed

      • Second malignancy probabilities in prostate cancer patients treated with SBRT and other contemporary radiation techniques. Radiother Oncol. 2021 08; 161:241-250. View in: Pubmed

      • Elective Pelvic Lymph Node Radiation in Prostate Cancer Revisited. J Clin Oncol. 2021 09 01; 39(25):2845-2846. View in: Pubmed

      • Comparative analysis of 1152 African-American and European-American men with prostate cancer identifies distinct genomic and immunological differences. Commun Biol. 2021 06 03; 4(1):670. View in: Pubmed

      • Racial and Ethnic Variation in PSA Testing and Prostate Cancer Incidence Following the 2012 USPSTF Recommendation. J Natl Cancer Inst. 2021 06 01; 113(6):719-726. View in: Pubmed

      • Association of Medicaid expansion and insurance status, cancer stage, treatment and mortality among patients with cervical cancer. Cancer Rep (Hoboken). 2021 12; 4(6):e1407. View in: Pubmed

      • Risk of cardiovascular mortality with androgen deprivation therapy in prostate cancer: A secondary analysis of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Randomized Controlled Trial. Cancer. 2021 07 01; 127(13):2213-2221. View in: Pubmed

      • Clinical characterization of radiation-associated muscle-invasive bladder cancer. Urology. 2021 08; 154:208-214. View in: Pubmed

      • Validation of a 22-Gene Genomic Classifier in Patients With Recurrent Prostate Cancer: An Ancillary Study of the NRG/RTOG 9601 Randomized Clinical Trial. JAMA Oncol. 2021 04 01; 7(4):544-552. View in: Pubmed

      • Financial worry and psychological distress among cancer survivors in the United States, 2013-2018. Support Care Cancer. 2021 Sep; 29(9):5523-5535. View in: Pubmed

      • Correlative analysis between two commercially available post-prostatectomy genomic tests. Prostate Cancer Prostatic Dis. 2021 06; 24(2):575-577. View in: Pubmed

      • Assessment of Simulated SARS-CoV-2 Infection and Mortality Risk Associated With Radiation Therapy Among Patients in 8 Randomized Clinical Trials. JAMA Netw Open. 2021 03 01; 4(3):e213304. View in: Pubmed

      • Intermediate clinical endpoints for surrogacy in localised prostate cancer: an aggregate meta-analysis. Lancet Oncol. 2021 03; 22(3):402-410. View in: Pubmed

      • Disparities in Refusal of Locoregional Treatment for Prostate Adenocarcinoma. JCO Oncol Pract. 2021 10; 17(10):e1489-e1501. View in: Pubmed

      • Association Between Travel Distance and Use of Postoperative Radiation Therapy Among Men With Organ-Confined Prostate Cancer: Does Geography Influence Treatment Decisions? Pract Radiat Oncol. 2021 Jul-Aug; 11(4):e426-e433. View in: Pubmed

      • Initial Management of Noncastrate Advanced, Recurrent, or Metastatic Prostate Cancer: ASCO Guideline Update. J Clin Oncol. 2021 Apr 10; 39(11):1274-1305. View in: Pubmed

      • A Systematic Review and Meta-analysis of Local Salvage Therapies After Radiotherapy for Prostate Cancer (MASTER). Eur Urol. 2021 09; 80(3):280-292. View in: Pubmed

      • Health care spending in prostate cancer: An assessment of characteristics and health care utilization of high resource-patients. Urol Oncol. 2021 02; 39(2):130.e17-130.e24. View in: Pubmed

      • A Systematic Review of the Evidence for the Decipher Genomic Classifier in Prostate Cancer. Eur Urol. 2021 03; 79(3):374-383. View in: Pubmed

      • Factors Influencing Noncompletion of Radiation Therapy Among Men With Localized Prostate Cancer. Int J Radiat Oncol Biol Phys. 2021 04 01; 109(5):1279-1285. View in: Pubmed

      • Development and Validation of a Clinical Prognostic Stage Group System for Nonmetastatic Prostate Cancer Using Disease-Specific Mortality Results From the International Staging Collaboration for Cancer of the Prostate. JAMA Oncol. 2020 12 01; 6(12):1912-1920. View in: Pubmed

      • Cognition and depression effects of androgen receptor axis-targeted drugs in men with prostate cancer: A systematic review. J Geriatr Oncol. 2021 06; 12(5):687-695. View in: Pubmed

      • The Case for Brachytherapy: Why It Deserves a Renaissance. Adv Radiat Oncol. 2021 Mar-Apr; 6(2):100605. View in: Pubmed

      • General and Health-Related Internet Use Among Cancer Survivors in the United States: A 2013-2018 Cross-Sectional Analysis. J Natl Compr Canc Netw. 2020 11; 18(11):1468-1475. View in: Pubmed

      • Development and Validation of a Genomic Tool to Predict Seminal Vesicle Invasion in Adenocarcinoma of the Prostate. JCO Precis Oncol. 2020 Nov; 4:1228-1238. View in: Pubmed

      • Assessment of Postprostatectomy Radiotherapy as Adjuvant or Salvage Therapy in Patients With Prostate Cancer: A Systematic Review. JAMA Oncol. 2020 Nov 01; 6(11):1793-1800. View in: Pubmed

      • Utilization of multimodality therapy with primary radical prostatectomy versus radiation therapy for Gleason 8-10 prostate cancer. Brachytherapy. 2021 Jan-Feb; 20(1):1-9. View in: Pubmed

      • Executive Summary of the American Radium Society Appropriate Use Criteria for Radiation Treatment of Node-Negative Muscle Invasive Bladder Cancer. Int J Radiat Oncol Biol Phys. 2021 03 15; 109(4):953-963. View in: Pubmed

      • Less Is More During COVID 19. Int J Radiat Oncol Biol Phys. 2020 10 01; 108(2):339. View in: Pubmed

      • Relative Timing of Radiotherapy and Androgen Deprivation for Prostate Cancer and Implications for Treatment During the COVID-19 Pandemic. JAMA Oncol. 2020 10 01; 6(10):1630-1632. View in: Pubmed

      • Quantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients. Prostate Cancer Prostatic Dis. 2021 06; 24(2):414-422. View in: Pubmed

      • Improving Diversity and Inclusion in the Post-Coronavirus Disease 2019 Era Through a Radiation Oncology Intensive Shadowing Experience (RISE). Adv Radiat Oncol. 2021 Jan-Feb; 6(1):100566. View in: Pubmed

      • Psychological Distress and Access to Mental Health Services Among Cancer Survivors: a National Health Interview Survey Analysis. J Gen Intern Med. 2021 10; 36(10):3243-3245. View in: Pubmed

      • Racial Differences in Genomic Profiling of Prostate Cancer. N Engl J Med. 2020 09 10; 383(11):1083-1085. View in: Pubmed

      • Disparities in Mortality from Larynx Cancer: Implications for Reducing Racial Differences. Laryngoscope. 2021 04; 131(4):E1147-E1155. View in: Pubmed

      • Re: Neal D. Shore, Fred Saad, Michael S. Cookson, et al. Oral Relugolix for Androgen-deprivation Therapy in Advanced Prostate Cancer. N Engl J Med 2020;382:2187-96. Eur Urol. 2020 11; 78(5):e195. View in: Pubmed

      • NRG Oncology Updated International Consensus Atlas on Pelvic Lymph Node Volumes for Intact and Postoperative Prostate Cancer. Int J Radiat Oncol Biol Phys. 2021 01 01; 109(1):174-185. View in: Pubmed

      • Mental Distress and Mental Health Services Receipt in Foreign-Born Survivors of Cancer: a National Health Interview Survey Analysis. J Gen Intern Med. 2021 08; 36(8):2495-2498. View in: Pubmed

      • Development and Validation of a Novel TP53 Mutation Signature That Predicts Risk of Metastasis in Primary Prostate Cancer. Clin Genitourin Cancer. 2021 06; 19(3):246-254.e5. View in: Pubmed

      • Three-tiered Subclassification System of High-risk Prostate Cancer in Men Managed With Radical Prostatectomy: Implications for Treatment Decision-making. Urology. 2020 11; 145:197-203. View in: Pubmed

      • Prostate cancer-specific mortality burden by risk group among men with localized disease: Implications for research and clinical trial priorities. Prostate. 2020 09; 80(13):1128-1133. View in: Pubmed

      • Impact of percent positive biopsy cores on cancer-specific mortality for patients with high-risk prostate cancer. Urol Oncol. 2020 09; 38(9):735.e9-735.e15. View in: Pubmed

      • To Radiate or Not to Radiate-The Challenges of Pelvic Reirradiation. Semin Radiat Oncol. 2020 Jul; 30(3):238-241. View in: Pubmed

      • Doublecortin Expression in Prostate Adenocarcinoma and Neuroendocrine Tumors. Int J Radiat Oncol Biol Phys. 2020 11 15; 108(4):936-940. View in: Pubmed

      • Transcriptomic Heterogeneity of Gleason Grade Group 5 Prostate Cancer. Eur Urol. 2020 09; 78(3):327-332. View in: Pubmed

      • Prostate cancer management costs vary by disease stage at presentation. Prostate Cancer Prostatic Dis. 2020 12; 23(4):564-566. View in: Pubmed

      • Addition of Androgen-Deprivation Therapy or Brachytherapy Boost to External Beam Radiotherapy for Localized Prostate Cancer: A Network Meta-Analysis of Randomized Trials. J Clin Oncol. 2020 09 10; 38(26):3024-3031. View in: Pubmed

      • Association of Presalvage Radiotherapy PSA Levels After Prostatectomy With Outcomes of Long-term Antiandrogen Therapy in Men With Prostate Cancer. JAMA Oncol. 2020 05 01; 6(5):735-743. View in: Pubmed

      • Surface applicator high-dose-rate fractionated brachytherapy for superficial cancers of the penis: A single-center case series and national database comparison. J Am Acad Dermatol. 2021 Jan; 84(1):168-172. View in: Pubmed

      • Local management of preinvasive and clinical T1-3 penile cancer: utilization of diverse treatment modalities. Future Oncol. 2020 May; 16(14):955-960. View in: Pubmed

      • Intermediate-risk Prostate Cancer: Stratification and Management. Eur Urol Oncol. 2020 06; 3(3):270-280. View in: Pubmed

      • Performance of clinicopathologic models in men with high risk localized prostate cancer: impact of a 22-gene genomic classifier. Prostate Cancer Prostatic Dis. 2020 12; 23(4):646-653. View in: Pubmed

      • Geographic Distribution of Racial Differences in Prostate Cancer Mortality. JAMA Netw Open. 2020 03 02; 3(3):e201839. View in: Pubmed

      • Changes in Length and Complexity of Clinical Practice Guidelines in Oncology, 1996-2019. JAMA Netw Open. 2020 03 02; 3(3):e200841. View in: Pubmed

      • Early Impact of the Affordable Care Act and Medicaid Expansion on Racial and Socioeconomic Disparities in Cancer Care. Am J Clin Oncol. 2020 03; 43(3):163-167. View in: Pubmed

      • Master Protocol Trial Design for Efficient and Rational Evaluation of Novel Therapeutic Oncology Devices. J Natl Cancer Inst. 2020 03 01; 112(3):229-237. View in: Pubmed

      • Validation of a subclassification for high-risk prostate cancer in a prospective cohort. Cancer. 2020 05 15; 126(10):2132-2138. View in: Pubmed

      • Trends, Quality, and Readability of Online Health Resources on Proton Radiation Therapy. Int J Radiat Oncol Biol Phys. 2020 05 01; 107(1):33-38. View in: Pubmed

      • Physician and facility drivers of spending variation in locoregional prostate cancer. Cancer. 2020 04 15; 126(8):1622-1631. View in: Pubmed

      • Genomic and clinical characterization of stromal infiltration markers in prostate cancer. Cancer. 2020 04 01; 126(7):1407-1412. View in: Pubmed

      • Addition of short-term androgen deprivation therapy to dose-escalated radiation therapy improves failure-free survival for select men with intermediate-risk prostate cancer. Ann Oncol. 2012 Sep; 23(9):2346-2352. View in: Pubmed

      • Prostate cancer incidence across stage, NCCN risk groups, and age before and after USPSTF Grade D recommendations against prostate-specific antigen screening in 2012. Cancer. 2020 02 15; 126(4):717-724. View in: Pubmed

      • An Update to Changing Patterns of Anal Carcinoma in the United States. Am J Clin Oncol. 2019 12; 42(12):887-897. View in: Pubmed

      • Risk of dementia following androgen deprivation therapy for treatment of prostate cancer. Prostate Cancer Prostatic Dis. 2020 09; 23(3):410-418. View in: Pubmed

      • Local Failure and Survival After Definitive Radiotherapy for Aggressive Prostate Cancer: An Individual Patient-level Meta-analysis of Six Randomized Trials. Eur Urol. 2020 02; 77(2):201-208. View in: Pubmed

      • Risk of Dementia and Depression in Young and Middle-aged Men Presenting with Nonmetastatic Prostate Cancer Treated with Androgen Deprivation Therapy. Eur Urol Oncol. 2021 02; 4(1):66-72. View in: Pubmed

      • Combined External Beam Radiation Therapy and Brachytherapy versus Radical Prostatectomy with Adjuvant Radiation Therapy for Gleason 9-10 Prostate Cancer. J Urol. 2019 11; 202(5):973-978. View in: Pubmed

      • United States trends in active surveillance or watchful waiting across patient socioeconomic status from 2010 to 2015. Prostate Cancer Prostatic Dis. 2020 03; 23(1):179-183. View in: Pubmed

      • Transcriptomic Heterogeneity of Androgen Receptor Activity Defines a de novo low AR-Active Subclass in Treatment Naïve Primary Prostate Cancer. Clin Cancer Res. 2019 11 15; 25(22):6721-6730. View in: Pubmed

      • Definitive and sustained increase in prostate cancer metastases in the United States. Urol Oncol. 2019 12; 37(12):988-990. View in: Pubmed

      • Comparing the Association Between Insurance and Mortality in Ovarian, Pancreatic, Lung, Colorectal, Prostate, and Breast Cancers. J Natl Compr Canc Netw. 2019 09 01; 17(9):1049-1058. View in: Pubmed

      • Using Stereotactic Body Radiotherapy to Overcome the Radioresistant Reputation of Renal Cell Carcinoma. Eur Urol Oncol. 2019 09; 2(5):524-525. View in: Pubmed

      • Practice Patterns and Outcomes Among Patients With N0M0 Prostate Cancer and a Very High Prostate-Specific Antigen Level. J Natl Compr Canc Netw. 2019 08 01; 17(8):941-948. View in: Pubmed

      • Genomic Validation of 3-Tiered Clinical Subclassification of High-Risk Prostate Cancer. Int J Radiat Oncol Biol Phys. 2019 11 01; 105(3):621-627. View in: Pubmed

      • Association of Black Race With Prostate Cancer-Specific and Other-Cause Mortality. JAMA Oncol. 2019 07 01; 5(7):975-983. View in: Pubmed

      • Conservative management of low-risk prostate cancer among young versus older men in the United States: Trends and outcomes from a novel national database. Cancer. 2019 10 01; 125(19):3338-3346. View in: Pubmed

      • Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients With Lung Cancer. J Am Coll Cardiol. 2019 06 18; 73(23):2976-2987. View in: Pubmed

      • Transcriptomic and Clinical Characterization of Neuropeptide Y Expression in Localized and Metastatic Prostate Cancer: Identification of Novel Prostate Cancer Subtype with Clinical Implications. Eur Urol Oncol. 2019 07; 2(4):405-412. View in: Pubmed

      • Association of Treatment With 5a-Reductase Inhibitors With Time to Diagnosis and Mortality in Prostate Cancer. JAMA Intern Med. 2019 06 01; 179(6):812-819. View in: Pubmed

      • Use and early mortality outcomes of active surveillance in patients with intermediate-risk prostate cancer. Cancer. 2019 09 15; 125(18):3164-3171. View in: Pubmed

      • Active Surveillance for Low-Risk Prostate Cancer in Black Patients. N Engl J Med. 2019 05 23; 380(21):2070-2072. View in: Pubmed

      • The current landscape of low-value care in men diagnosed with prostate cancer: what is the role of individual hospitals? Urol Oncol. 2019 09; 37(9):575.e9-575.e18. View in: Pubmed

      • Quality of Life in Patients With Low-Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy: A Phase 3 Randomized Clinical Trial. JAMA Oncol. 2019 May 01; 5(5):664-670. View in: Pubmed

      • Evolution of Radiation Oncology in Pakistan. Int J Radiat Oncol Biol Phys. 2019 09 01; 105(1):11-16. View in: Pubmed

      • Novel RB1-Loss Transcriptomic Signature Is Associated with Poor Clinical Outcomes across Cancer Types. Clin Cancer Res. 2019 Jul 15; 25(14):4290-4299. View in: Pubmed

      • Prostate-only Versus Whole-pelvis Radiation with or Without a Brachytherapy Boost for Gleason Grade Group 5 Prostate Cancer: A Retrospective Analysis. Eur Urol. 2020 01; 77(1):3-10. View in: Pubmed

      • Stereotactic Body Radiation Therapy for Localized Prostate Cancer: A Systematic Review and Meta-Analysis of Over 6,000 Patients Treated On Prospective Studies. Int J Radiat Oncol Biol Phys. 2019 07 15; 104(4):778-789. View in: Pubmed

      • Facility Level Variation in Rates of Definitive Therapy for Low Risk Prostate Cancer in Men with Limited Life Expectancy: An Opportunity for Value Based Care Redesign. J Urol. 2019 04; 201(4):728-734. View in: Pubmed

      • Quality of Care in the Treatment of Localized Intermediate and High Risk Prostate Cancer at Minority Serving Hospitals. J Urol. 2019 04; 201(4):735-741. View in: Pubmed

      • The Immune Landscape of Prostate Cancer and Nomination of PD-L2 as a Potential Therapeutic Target. J Natl Cancer Inst. 2019 03 01; 111(3):301-310. View in: Pubmed

      • Antiviral therapy and the development of osteopenia/osteoporosis among Asians with chronic hepatitis B. J Med Virol. 2019 07; 91(7):1288-1294. View in: Pubmed

      • Readressing the rationale of irradiation in stage I seminoma guidelines: a critical essay. BJU Int. 2019 07; 124(1):35-39. View in: Pubmed

      • Use of Active Surveillance or Watchful Waiting for Low-Risk Prostate Cancer and Management Trends Across Risk Groups in the United States, 2010-2015. JAMA. 2019 Feb 19; 321(7):704-706. View in: Pubmed

      • A National Survey of Radiation Oncologists and Urologists on Perceived Attitudes and Recommendations of Active Surveillance for Low-Risk Prostate Cancer. Clin Genitourin Cancer. 2019 06; 17(3):e472-e481. View in: Pubmed

      • Underutilization of Androgen Deprivation Therapy with External Beam Radiotherapy in Men with High-grade Prostate Cancer. Eur Urol Oncol. 2021 04; 4(2):327-330. View in: Pubmed

      • Postoperative Radiation Therapy in Localized Prostate Cancer: When, How Much, and How Fast? Int J Radiat Oncol Biol Phys. 2019 02 01; 103(2):289-292. View in: Pubmed

      • Prostate Cancer Genomic-risk Differences Between African-American and White Men Across Gleason Scores. Eur Urol. 2019 06; 75(6):1038-1040. View in: Pubmed

      • Impact of tumor, treatment, and access on outcomes in bladder cancer: Can equal access overcome race-based differences in survival? Cancer. 2019 04 15; 125(8):1319-1329. View in: Pubmed

      • A comparative analysis of overall survival between high-dose-rate and low-dose-rate brachytherapy boosts for unfavorable-risk prostate cancer. Brachytherapy. 2019 Mar - Apr; 18(2):186-191. View in: Pubmed

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      • Effects of Androgen Deprivation Therapy on Pain Perception, Quality of Life, and Depression in Men With Prostate Cancer. J Pain Symptom Manage. 2018 02; 55(2):307-317.e1. View in: Pubmed

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      • Efficacy of Local Treatment in Prostate Cancer Patients with Clinically Pelvic Lymph Node-positive Disease at Initial Diagnosis. Eur Urol. 2018 Mar; 73(3):452-461. View in: Pubmed

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      • Racial Disparity in Delivering Definitive Therapy for Intermediate/High-risk Localized Prostate Cancer: The Impact of Facility Features and Socioeconomic Characteristics. Eur Urol. 2018 Mar; 73(3):445-451. View in: Pubmed

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      • A novel approach to an automated needle insertion in brachytherapy procedures. Med Biol Eng Comput. 2018 Feb; 56(2):273-287. View in: Pubmed

      • A Systematic Review and Framework for the Use of Hormone Therapy with Salvage Radiation Therapy for Recurrent Prostate Cancer. Eur Urol. 2018 02; 73(2):156-165. View in: Pubmed

      • The Use of Prostate Specific Antigen Screening in Purchased versus Direct Care Settings: Data from the TRICARE® Military Database. J Urol. 2017 12; 198(6):1295-1300. View in: Pubmed

      • Contemporary Treatment Patterns and Outcomes for Clinical Stage IS Testicular Cancer. Eur Urol. 2018 02; 73(2):262-270. View in: Pubmed

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      • Ability of a Genomic Classifier to Predict Metastasis and Prostate Cancer-specific Mortality after Radiation or Surgery based on Needle Biopsy Specimens. Eur Urol. 2017 11; 72(5):845-852. View in: Pubmed

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      • Comparative Effectiveness of Trimodal Therapy Versus Radical Cystectomy for Localized Muscle-invasive Urothelial Carcinoma of the Bladder. Eur Urol. 2017 10; 72(4):483-487. View in: Pubmed

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      • Real-world experience with interferon-free, direct acting antiviral therapies in Asian Americans with chronic hepatitis C and advanced liver disease. Medicine (Baltimore). 2017 Feb; 96(6):e6128. View in: Pubmed

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      • Value of Extra-Early Initiation of Salvage Radiation for Increasing Prostate-Specific Antigen After Prostatectomy. J Clin Oncol. 2016 Oct 20; 34(30):3597-3599. View in: Pubmed

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      • Prostate Brachytherapy Case Volumes by Academic and Nonacademic Practices: Implications for Future Residency Training. Int J Radiat Oncol Biol Phys. 2016 11 01; 96(3):624-8. View in: Pubmed

      • Sex differences in disease presentation, treatment and clinical outcomes of patients with hepatocellular carcinoma: a single-centre cohort study. BMJ Open Gastroenterol. 2016; 3(1):e000107. View in: Pubmed

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      • Recent relocation and decreased survival following a cancer diagnosis. Prev Med. 2016 08; 89:245-250. View in: Pubmed

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      • The influence of marital status on the use of breast, cervical, and colorectal cancer screening. Prev Med. 2016 08; 89:140-145. View in: Pubmed

      • Surgeon and Hospital Level Variation in the Costs of Robot-Assisted Radical Prostatectomy. J Urol. 2016 Oct; 196(4):1090-5. View in: Pubmed

      • Association of Androgen Deprivation Therapy With Depression in Localized Prostate Cancer. J Clin Oncol. 2016 06 01; 34(16):1905-12. View in: Pubmed

      • Randomized Phase III Noninferiority Study Comparing Two Radiotherapy Fractionation Schedules in Patients With Low-Risk Prostate Cancer. J Clin Oncol. 2016 07 10; 34(20):2325-32. View in: Pubmed

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      • Variation in National Use of Long-Term ADT by Disease Aggressiveness Among Men With Unfavorable-Risk Prostate Cancer. J Natl Compr Canc Netw. 2016 04; 14(4):421-8. View in: Pubmed

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      • Individual Patient Data Analysis of Randomized Clinical Trials: Impact of Black Race on Castration-resistant Prostate Cancer Outcomes. Eur Urol Focus. 2016 Dec; 2(5):532-539. View in: Pubmed

      • ACR Appropriateness Criteria Renal Cell Carcinoma Staging. J Am Coll Radiol. 2016 May; 13(5):518-25. View in: Pubmed

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      • High-Dose-Rate Monotherapy for Localized Prostate Cancer-What More Will It Take to Make This a Standard Therapy? Int J Radiat Oncol Biol Phys. 2016 Mar 15; 94(4):655-6. View in: Pubmed

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      • Common variation in BRCA1 may have a role in progression to lethal prostate cancer after radiation treatment. Prostate Cancer Prostatic Dis. 2016 06; 19(2):197-201. View in: Pubmed

      • Association Between Very Small Tumor Size and Increased Cancer-Specific Mortality in Node-Positive Colon Cancer. Dis Colon Rectum. 2016 Mar; 59(3):187-93. View in: Pubmed

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      • Editorial comment. Urology. 2016 Jan; 87:152. View in: Pubmed

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      • Association Between Treatment at a High-Volume Facility and Improved Survival for Radiation-Treated Men With High-Risk Prostate Cancer. Int J Radiat Oncol Biol Phys. 2016 Mar 15; 94(4):683-90. View in: Pubmed

      • The Landscape of Prognostic Outlier Genes in High-Risk Prostate Cancer. Clin Cancer Res. 2016 Apr 01; 22(7):1777-86. View in: Pubmed

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      • Closing the Cancer Divide Through Ubuntu: Information and Communication Technology-Powered Models for Global Radiation Oncology. Int J Radiat Oncol Biol Phys. 2016 Mar 01; 94(3):440-9. View in: Pubmed

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      • Prostate cancer screening in men 75 years old or older: an assessment of self-reported health status and life expectancy. J Urol. 2010 May; 183(5):1798-802. View in: Pubmed

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      • The association between biological subtype and isolated regional nodal failure after breast-conserving therapy. Int J Radiat Oncol Biol Phys. 2010 May 01; 77(1):188-96. View in: Pubmed

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