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Steven J. Mentzer, MD


Surgical Oncology

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Physician

  • Professor of Surgery, Harvard Medical School

Clinical Interests

  • Esophageal cancer
  • Hyperhidrosis and neurogenic tumors
  • Lung and pleural cancer
  • Lung transplantation
  • Mediastinal tumors
  • Minimally invasive and robotic thoracic surgery

Diseases Treated

  • Lung Cancer, non-small cell
  • Lung Cancer, small cell

Contact Information

  • Office Phone Number617-732-6703
  • Fax617-730-2898

Bio

Dr. Mentzer received his MD in 1981 from the University of Minnesota. He completed his general surgery training at Brigham and Women's Hospital and his cardiothoracic surgery fellowship at the University of Toronto. He also completed a research fellowship at DFCI, where he investigated the molecular mechanisms involved in the regulation of T lymphocyte function. He is board certified in general surgery, cardiothoracic surgery, and surgical critical care.

Board Certification:

  • Surgery, 1989
  • Surgical Critical Care, 1994
  • Thoracic Surgery, 1991

Fellowship:

  • Toronto General Hospital, Thoracic Surgery

Residency:

  • Brigham and Women's Hospital, General Surgery

Medical School:

  • University of Minnesota, Minneapolis School of Medicine

Research

Mechanisms of Lymphocyte Recirculation and Recruitment

In the mammalian immune system, cell migration plays an important role in the host defense against a variety of antigenic challenges. Cell migration is the process that delivers lymphocytes to virally infected tissues, organ allografts, or growing tumors. Understanding the mechanism of lymphocyte homing to the site of antigen challenge offers the potential for regulating this process clinically. For example, it would be desirable to enhance lymphocyte migration into virally infected tissues and malignant tumors, but suppress lymphocyte migration into organ allografts.In recent years, attempts to define the mechanism of lymphocyte homing to the site of inflammation have focused on cell adhesion molecules. These molecules are expressed on the cell surface and appear to regulate the interaction of lymphocytes with the endothelial cells that line the vessel wall. Our approach was to study the function of these molecules under physiologic conditions both in vitro and in vivo. Using a video microscopy chamber to simulate flow conditions in the inflammatory microcirculation, we studied the contribution of these cell adhesion molecules to lymphocyte movement, adhesion, and locomotion. The regulation of lymphocyte migration can be clarified by selectively inhibiting or augmenting the function of these cell adhesion molecules.Cell migration to the site of antigen challenge is a process that involves not only lymphocytes and endothelial cells, but complex microhemodynamic forces as well. The forces at the vessel wall appear to be important determinants of whether cells exit the microcirculation or remain in the flow stream. For example, during lymphocytic inflammation, microhemodynamic forces can vary widely as the microcirculation undergoes dramatic structural adaptation. It is possible that these structural changes facilitate lymphocyte transmigration. To study the effect of microhemodynamic forces on lymphocyte migration, we tracked migrating lymphocytes from the efferent lymph to the antigen-stimulated microcirculation. Using fluorescence and dark-field intravital video microscopy, we directly observed the movements of cells in the microcirculation. Defining the molecular and physiologic mechanisms of lymphocyte migration into the inflammatory tissue has led to new approaches to the inhibition and augmentation of cell migration in vivo.

Kienzle A, Servais AB, Ysasi AB, Gibney BC, Valenzuela CD, Wagner WL, Ackermann M, Mentzer SJ. Free-Floating Mesothelial Cells in Pleural Fluid After Lung Surgery. Front Med (Lausanne). 2018; 5:89.
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Mentzer SJ. The puzzling mechanism of compensatory lung growth. Stem Cell Investig. 2018; 5:8.
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Servais AB, Valenzuela CD, Kienzle A, Ysasi AB, Wagner WL, Tsuda A, Ackermann M, Mentzer SJ. Functional Mechanics of a Pectin-Based Pleural Sealant after Lung Injury. Tissue Eng Part A. 2018 May; 24(9-10):695-702.
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Mentzer SJ, Tsuda A, Loring SH. Pleural mechanics and the pathophysiology of air leaks. J Thorac Cardiovasc Surg. 2018 May; 155(5):2182-2189.
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Gibney BC, Wagner WL, Ysasi AB, Belle JM, Tsuda A, Ackermann M, Mentzer SJ. Structural and functional evidence for the scaffolding effect of alveolar blood vessels. Exp Lung Res. 2017 Nov - Dec; 43(9-10):337-346.
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White A, Kucukak S, Bueno R, Servais E, Lee DN, Colson Y, Jaklitsch M, McNamee C, Mentzer S, Wee J, Swanson SJ. Pneumonectomy is safe and effective for non-small cell lung cancer following induction therapy. J Thorac Dis. 2017 Nov; 9(11):4447-4453.
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Ackermann M, Gaumann A, Mentzer SJ, Hinrichs JB, Warnecke G, Hoeper MM, Braubach P, Kuehnel M, Maegel L, Jonigk D. Plexiform Vasculopathy in Chronic Thromboembolic Pulmonary Hypertension. Am J Respir Crit Care Med. 2017 10 15; 196(8):e48-e51.
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George E, Barile M, Tang A, Wiesel O, Coppolino A, Giannopoulos A, Mentzer S, Jaklitsch M, Hunsaker A, Mitsouras D. Utility and reproducibility of 3-dimensional printed models in pre-operative planning of complex thoracic tumors. J Surg Oncol. 2017 Sep; 116(3):407-415.
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Servais AB, Kienzle A, Valenzuela CD, Ysasi AB, Wagner WL, Tsuda A, Ackermann M, Mentzer SJ. Structural Heteropolysaccharide Adhesion to the Glycocalyx of Visceral Mesothelium. Tissue Eng Part A. 2018 Feb; 24(3-4):199-206.
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Ysasi AB, Wagner WL, Valenzuela CD, Kienzle A, Servais AB, Bennett RD, Tsuda A, Ackermann M, Mentzer SJ. Evidence for pleural epithelial-mesenchymal transition in murine compensatory lung growth. PLoS One. 2017; 12(5):e0177921.
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Valenzuela CD, Wagner WL, Bennett RD, Ysasi AB, Belle JM, Molter K, Straub BK, Wang D, Chen Z, Ackermann M, Tsuda A, Mentzer SJ. Extracellular Assembly of the Elastin Cable Line Element in the Developing Lung. Anat Rec (Hoboken). 2017 Sep; 300(9):1670-1679.
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Haber S, Weisbord M, Mentzer SJ, Tsuda A. Alveolar septal patterning during compensatory lung growth: Part II the effect of parenchymal pressure gradients. J Theor Biol. 2017 May 21; 421:168-178.
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Ackermann M, Kim YO, Wagner WL, Schuppan D, Valenzuela CD, Mentzer SJ, Kreuz S, Stiller D, Wollin L, Konerding MA. Effects of nintedanib on the microvascular architecture in a lung fibrosis model. Angiogenesis. 2017 Aug; 20(3):359-372.
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Ackermann M, Mentzer SJ, Roth W, Geisthoff U, Stoelben E. Pulmonary microvascular architecture in hereditary haemorrhagic telangiectasia. Thorax. 2017 09; 72(9):861-863.
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Bennett RD, Ysasi AB, Wagner WL, Valenzuela CD, Tsuda A, Pyne S, Li S, Grimsby J, Pokharel P, Livak KJ, Ackermann M, Blainey P, Mentzer SJ. Deformation-induced transitional myofibroblasts contribute to compensatory lung growth. Am J Physiol Lung Cell Mol Physiol. 2017 Jan 01; 312(1):L79-L88.
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Cleary JM, Mamon HJ, Szymonifka J, Bueno R, Choi N, Donahue DM, Fidias PM, Gaissert HA, Jaklitsch MT, Kulke MH, Lynch TP, Mentzer SJ, Meyerhardt JA, Swanson RS, Wain J, Fuchs CS, Enzinger PC. Neoadjuvant irinotecan, cisplatin, and concurrent radiation therapy with celecoxib for patients with locally advanced esophageal cancer. BMC Cancer. 2016 07 13; 16:468.
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Haber S, Weisbord M, Mishima M, Mentzer SJ, Tsuda A. Interstitial fluid flow of alveolar primary septa after pneumonectomy. J Theor Biol. 2016 07 07; 400:118-28.
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Wagner W, Bennett RD, Ackermann M, Ysasi AB, Belle J, Valenzuela CD, Pabst A, Tsuda A, Konerding MA, Mentzer SJ. Elastin Cables Define the Axial Connective Tissue System in the Murine Lung. Anat Rec (Hoboken). 2015 Nov; 298(11):1960-8.
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Föhst S, Wagner W, Ackermann M, Redenbach C, Schladitz K, Wirjadi O, Ysasi AB, Mentzer SJ, Konerding MA. Three-dimensional image analytical detection of intussusceptive pillars in murine lung. J Microsc. 2015 Dec; 260(3):326-37.
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Ysasi AB, Wagner WL, Bennett RD, Ackermann M, Valenzuela CD, Belle J, Tsuda A, Konerding MA, Mentzer SJ. Remodeling of alveolar septa after murine pneumonectomy. Am J Physiol Lung Cell Mol Physiol. 2015 Jun 15; 308(12):L1237-44.
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Bennett RD, Ysasi AB, Belle JM, Wagner WL, Konerding MA, Blainey PC, Pyne S, Mentzer SJ. Laser microdissection of the alveolar duct enables single-cell genomic analysis. Front Oncol. 2014; 4:260.
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Belle J, Ysasi A, Bennett RD, Filipovic N, Nejad MI, Trumper DL, Ackermann M, Wagner W, Tsuda A, Konerding MA, Mentzer SJ. Stretch-induced intussuceptive and sprouting angiogenesis in the chick chorioallantoic membrane. Microvasc Res. 2014 Sep; 95:60-7.
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Mentzer SJ, Konerding MA. Intussusceptive angiogenesis: expansion and remodeling of microvascular networks. Angiogenesis. 2014 Jul; 17(3):499-509.
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Mohiuddin K, Haneuse S, Sofer T, Gill R, Jaklitsch MT, Colson YL, Wee J, Bueno R, Mentzer SJ, Sugarbaker DJ, Swanson SJ. Relationship between margin distance and local recurrence among patients undergoing wedge resection for small (=2 cm) non-small cell lung cancer. J Thorac Cardiovasc Surg. 2014 Apr; 147(4):1169-75; discussion 1175-7.
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Ackermann M, Houdek JP, Gibney BC, Ysasi A, Wagner W, Belle J, Schittny JC, Enzmann F, Tsuda A, Mentzer SJ, Konerding MA. Sprouting and intussusceptive angiogenesis in postpneumonectomy lung growth: mechanisms of alveolar neovascularization. Angiogenesis. 2014 Jul; 17(3):541-51.
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Filipovic N, Gibney BC, Kojic M, Nikolic D, Isailovic V, Ysasi A, Konerding MA, Mentzer SJ, Tsuda A. Mapping cyclic stretch in the postpneumonectomy murine lung. J Appl Physiol (1985). 2013 Nov 01; 115(9):1370-8.
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Ysasi AB, Belle JM, Gibney BC, Fedulov AV, Wagner W, Konerding MA, Mentzer SJ. Effect of unilateral diaphragmatic paralysis on postpneumonectomy lung growth. Am J Physiol Lung Cell Mol Physiol. 2013 Sep 15; 305(6):L439-45.
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Oxman DA, Issa NC, Marty FM, Patel A, Panizales CZ, Johnson NN, Licona JH, McKenna SS, Frendl G, Mentzer SJ, Jaklitsch MT, Bueno R, Colson Y, Swanson SJ, Sugarbaker DJ, Baden LR. Postoperative antibacterial prophylaxis for the prevention of infectious complications associated with tube thoracostomy in patients undergoing elective general thoracic surgery: a double-blind, placebo-controlled, randomized trial. JAMA Surg. 2013 May; 148(5):440-6.
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Chamoto K, Gibney BC, Ackermann M, Lee GS, Konerding MA, Tsuda A, Mentzer SJ. Alveolar epithelial dynamics in postpneumonectomy lung growth. Anat Rec (Hoboken). 2013 Mar; 296(3):495-503.
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Ackermann M, Tsuda A, Secomb TW, Mentzer SJ, Konerding MA. Intussusceptive remodeling of vascular branch angles in chemically-induced murine colitis. Microvasc Res. 2013 May; 87:75-82.
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Chamoto K, Gibney BC, Lee GS, Ackermann M, Konerding MA, Tsuda A, Mentzer SJ. Migration of CD11b+ accessory cells during murine lung regeneration. Stem Cell Res. 2013 May; 10(3):267-77.
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Gibney BC, Park MA, Chamoto K, Ysasi A, Konerding MA, Tsuda A, Mentzer SJ. Detection of murine post-pneumonectomy lung regeneration by 18FDG PET imaging. EJNMMI Res. 2012 Sep 21; 2(1):48.
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Filipovic N, Gibney BC, Nikolic D, Konerding MA, Mentzer SJ, Tsuda A. Computational analysis of lung deformation after murine pneumonectomy. [corrected]. Comput Methods Biomech Biomed Engin. 2014; 17(8):838-44.
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Chamoto K, Gibney BC, Ackermann M, Lee GS, Lin M, Konerding MA, Tsuda A, Mentzer SJ. Alveolar macrophage dynamics in murine lung regeneration. J Cell Physiol. 2012 Sep; 227(9):3208-15.
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Gibney BC, Houdek JP, Chamoto K, Lee GS, Ackermann M, Lin M, Collings-Simpson D, Konerding MA, Tsuda A, Mentzer SJ. Mechanostructural adaptations preceding postpneumonectomy lung growth. Exp Lung Res. 2012 Oct; 38(8):396-405.
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Butler JP, Loring SH, Patz S, Tsuda A, Yablonskiy DA, Mentzer SJ. Evidence for adult lung growth in humans. N Engl J Med. 2012 Jul 19; 367(3):244-7.
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Gibney BC, Chamoto K, Lee GS, Simpson DC, Miele LF, Tsuda A, Konerding MA, Wagers A, Mentzer SJ. Cross-circulation and cell distribution kinetics in parabiotic mice. J Cell Physiol. 2012 Feb; 227(2):821-8.
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Wolf AS, Richards WG, Jaklitsch MT, Gill R, Chirieac LR, Colson YL, Mohiuddin K, Mentzer SJ, Bueno R, Sugarbaker DJ, Swanson SJ. Lobectomy versus sublobar resection for small (2 cm or less) non-small cell lung cancers. Ann Thorac Surg. 2011 Nov; 92(5):1819-23; discussion 1824-5.
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Konerding MA, Gibney BC, Houdek JP, Chamoto K, Ackermann M, Lee GS, Lin M, Tsuda A, Mentzer SJ. Spatial dependence of alveolar angiogenesis in post-pneumonectomy lung growth. Angiogenesis. 2012 Mar; 15(1):23-32.
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Erba P, Miele LF, Adini A, Ackermann M, Lamarche JM, Orgill BD, D'Amato RJ, Konerding MA, Mentzer SJ, Orgill DP. A morphometric study of mechanotransductively induced dermal neovascularization. Plast Reconstr Surg. 2011 Oct; 128(4):288e-299e.
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Chamoto K, Gibney BC, Lee GS, Lin M, Collings-Simpson D, Voswinckel R, Konerding MA, Tsuda A, Mentzer SJ. CD34+ progenitor to endothelial cell transition in post-pneumonectomy angiogenesis. Am J Respir Cell Mol Biol. 2012 Mar; 46(3):283-9.
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Rossin E, Lin TI, Ho HJ, Mentzer SJ, Pyne S. A framework for analytical characterization of monoclonal antibodies based on reactivity profiles in different tissues. Bioinformatics. 2011 Oct 01; 27(19):2746-53.
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Lin M, Chamoto K, Gibney BC, Lee GS, Collings-Simpson D, Houdek J, Konerding MA, Tsuda A, Mentzer SJ. Angiogenesis gene expression in murine endothelial cells during post-pneumonectomy lung growth. Respir Res. 2011 Jul 27; 12:98.
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Gibney BC, Lee GS, Houdek JP, Lin M, Miele LF, Chamoto K, Konerding MA, Tsuda A, Mentzer SJ. Dynamic determination of oxygenation and lung compliance in murine pneumonectomy. Exp Lung Res. 2011 Jun; 37(5):301-9.
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Lee GS, Filipovic N, Lin M, Gibney BC, Simpson DC, Konerding MA, Tsuda A, Mentzer SJ. Intravascular pillars and pruning in the extraembryonic vessels of chick embryos. Dev Dyn. 2011 Jun; 240(6):1335-43.
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Erba P, Ogawa R, Ackermann M, Adini A, Miele LF, Dastouri P, Helm D, Mentzer SJ, D'Amato RJ, Murphy GF, Konerding MA, Orgill DP. Angiogenesis in wounds treated by microdeformational wound therapy. Ann Surg. 2011 Feb; 253(2):402-9.
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Lee GS, Filipovic N, Miele LF, Lin M, Simpson DC, Giney B, Konerding MA, Tsuda A, Mentzer SJ. Blood flow shapes intravascular pillar geometry in the chick chorioallantoic membrane. J Angiogenes Res. 2010 Jul 07; 2:11.
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Konerding MA, Turhan A, Ravnic DJ, Lin M, Fuchs C, Secomb TW, Tsuda A, Mentzer SJ. Inflammation-induced intussusceptive angiogenesis in murine colitis. Anat Rec (Hoboken). 2010 May; 293(5):849-57.
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Caglar HB, Baldini EH, Othus M, Rabin MS, Bueno R, Sugarbaker DJ, Mentzer SJ, Jänne PA, Johnson BE, Allen AM. Outcomes of patients with stage III nonsmall cell lung cancer treated with chemotherapy and radiation with and without surgery. Cancer. 2009 Sep 15; 115(18):4156-66.
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Pratt JP, Zeng Q, Ravnic D, Huss H, Rawn J, Mentzer SJ. Hierarchical clustering of monoclonal antibody reactivity patterns in nonhuman species. Cytometry A. 2009 Sep; 75(9):734-42.
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Filipovic N, Tsuda A, Lee GS, Miele LF, Lin M, Konerding MA, Mentzer SJ. Computational flow dynamics in a geometric model of intussusceptive angiogenesis. Microvasc Res. 2009 Dec; 78(3):286-93.
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Miele LF, Turhan A, Lee GS, Lin M, Ravnic D, Tsuda A, Konerding MA, Mentzer SJ. Blood flow patterns spatially associated with platelet aggregates in murine colitis. Anat Rec (Hoboken). 2009 Aug; 292(8):1143-53.
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Sugarbaker DJ, Tilleman TR, Swanson SJ, Jaklitsch MT, Mentzer SJ, Mujoomdar AA, Bueno R. The role of extrapleural pneumonectomy in the management of pleural cancers. J Clin Oncol. 2009 May 20; 27(15_suppl):7577.
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Turhan A, Lin M, Lee GS, Miele LF, Tsuda A, Konerding MA, Mentzer SJ. Vascular microarchitecture of murine colitis-associated lymphoid angiogenesis. Anat Rec (Hoboken). 2009 May; 292(5):621-32.
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Lee GS, Miele LF, Turhan A, Lin M, Hanidziar D, Konerding MA, Mentzer SJ. Spatial calibration of structured illumination fluorescence microscopy using capillary tissue phantoms. Microsc Res Tech. 2009 Feb; 72(2):85-92.
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Tsuda A, Turhan A, Konerding M, Ravnic D, Hanidziar D, Lin M, Mentzer SJ. Bimodal oscillation frequencies of blood flow in the inflammatory colon microcirculation. Anat Rec (Hoboken). 2009 Jan; 292(1):65-72.
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Turhan A, Tsuda A, Konerding MA, Lin M, Miele L, Lee G, Mentzer SJ. Effect of intraluminal pillars on particle motion in bifurcated microchannels. In Vitro Cell Dev Biol Anim. 2008 Nov-Dec; 44(10):426-33.
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Allen AM, Mentzer SJ, Yeap BY, Soto R, Baldini EH, Rabin MS, Sugarbaker DJ, Bueno R. Pneumonectomy after chemoradiation: the Dana-Farber Cancer Institute/Brigham and Women's Hospital experience. Cancer. 2008 Mar 01; 112(5):1106-13.
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Turhan A, Konerding MA, Tsuda A, Ravnic DJ, Hanidziar D, Lin M, Mentzer SJ. Bridging mucosal vessels associated with rhythmically oscillating blood flow in murine colitis. Anat Rec (Hoboken). 2008 Jan; 291(1):74-82.
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Allen AM, Rabin MS, Reilly JJ, Mentzer SJ. Unresectable adenoid cystic carcinoma of the trachea treated with chemoradiation. J Clin Oncol. 2007 Dec 01; 25(34):5521-3.
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Pietramaggiori G, Liu P, Scherer SS, Kaipainen A, Prsa MJ, Mayer H, Newalder J, Alperovich M, Mentzer SJ, Konerding MA, Huang S, Ingber DE, Orgill DP. Tensile forces stimulate vascular remodeling and epidermal cell proliferation in living skin. Ann Surg. 2007 Nov; 246(5):896-902.
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Filipovic N, Ravnic D, Kojic M, Mentzer SJ, Haber S, Tsuda A. Interactions of blood cell constituents: experimental investigation and computational modeling by discrete particle dynamics algorithm. Microvasc Res. 2008 Mar; 75(2):279-84.
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Paul S, Kurtz M, Mentzer SJ. Osteomalacia associated with a fibroblast growth factor-23 secreting chest wall tumor. J Thorac Cardiovasc Surg. 2007 Sep; 134(3):803-5.
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Ravnic DJ, Zhang YZ, Turhan A, Tsuda A, Pratt JP, Huss HT, Mentzer SJ. Biological and optical properties of fluorescent nanoparticles developed for intravascular imaging. Microsc Res Tech. 2007 Sep; 70(9):776-81.
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Chang MY, Mentzer SJ, Colson YL, Linden PA, Jaklitsch MT, Lipsitz SR, Sugarbaker DJ. Factors predicting poor survival after resection of stage IA non-small cell lung cancer. J Thorac Cardiovasc Surg. 2007 Oct; 134(4):850-6.
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Ravnic DJ, Konerding MA, Huss HT, Wolloscheck T, Pratt JP, Mentzer SJ. Murine microvideo endoscopy of the colonic microcirculation. J Surg Res. 2007 Sep; 142(1):97-103.
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Loring SH, Mentzer SJ, Reilly JJ. Sources of graft restriction after single lung transplantation for emphysema. J Thorac Cardiovasc Surg. 2007 Jul; 134(1):204-9.
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Li Y, Chang Q, Rubin BP, Fletcher CD, Morgan TW, Mentzer SJ, Sugarbaker DJ, Fletcher JA, Xiao S. Insulin receptor activation in solitary fibrous tumours. J Pathol. 2007 Apr; 211(5):550-4.
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Linden PA, Bueno R, Mentzer SJ, Zellos L, Lebenthal A, Colson YL, Sugarbaker DJ, Jaklitsch MT. Modified T-tube repair of delayed esophageal perforation results in a low mortality rate similar to that seen with acute perforations. Ann Thorac Surg. 2007 Mar; 83(3):1129-33.
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Ravnic DJ, Konerding MA, Pratt JP, Wolloscheck T, Huss HT, Mentzer SJ. The murine bronchopulmonary microcirculation in hapten-induced inflammation. J Thorac Cardiovasc Surg. 2007 Jan; 133(1):97-103.
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Mentzer SJ. Optimizing the selection of surgical candidates for lung volume reduction surgery. Semin Thorac Cardiovasc Surg. 2007; 19(2):151-6.
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Ravnic DJ, Konerding M, Pratt JP, Wolloscheck T, Huss HT, Mentzer SJ. Inflammation-responsive focal constrictors in the mouse ear microcirculation. J Anat. 2006 Dec; 209(6):807-16.
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Perrine SP, Hermine O, Small T, Suarez F, O'Reilly R, Boulad F, Fingeroth J, Askin M, Levy A, Mentzer SJ, Di Nicola M, Gianni AM, Klein C, Horwitz S, Faller DV. A phase 1/2 trial of arginine butyrate and ganciclovir in patients with Epstein-Barr virus-associated lymphoid malignancies. Blood. 2007 Mar 15; 109(6):2571-8.
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Ravnic DJ, Konerding MA, Tsuda A, Huss HT, Wolloscheck T, Pratt JP, Mentzer SJ. Structural adaptations in the murine colon microcirculation associated with hapten-induced inflammation. Gut. 2007 Apr; 56(4):518-23.
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Ravnic DJ, Tsuda A, Turhan A, Pratt JP, Huss HT, Zhang YZ, Mentzer SJ. Multiframe particle tracking in intravital imaging: defining Lagrangian coordinates in the microcirculation. Biotechniques. 2006 Nov; 41(5):597-601.
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Ravnic DJ, Zhang YZ, Tsuda A, Pratt JP, Huss HT, Mentzer SJ. Multi-image particle tracking velocimetry of the microcirculation using fluorescent nanoparticles. Microvasc Res. 2006 Jul-Sep; 72(1-2):27-33.
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Zeng QT, Pratt JP, Pak J, Ravnic D, Huss H, Mentzer SJ. Feature-guided clustering of multi-dimensional flow cytometry datasets. J Biomed Inform. 2007 Jun; 40(3):325-31.
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Faller DV, Hermine O, Small T, Suarez F, O'Reilly R, Boulad F, Fingeroth J, Mentzer SJ, Klein C, Horwitz S, Perrine SP. Phase I/II trial of Arginine Butyrate and ganciclovir in Epstein-Barr virus-associated lymphoid malignancies. J Clin Oncol. 2006 Jun 20; 24(18_suppl):7542.
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Jiang X, Pratt JP, Huss HO, Ravnic DJ, Mentzer SJ. Structural mapping of immunoglobulin subclasses using multiplexed bead flow cytometry. Hybridoma (Larchmt). 2006 Jun; 25(3):133-8.
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Pratt JP, Ravnic DJ, Huss HT, Jiang X, Orozco BS, Mentzer SJ. Melittin-induced membrane permeability: a nonosmotic mechanism of cell death. In Vitro Cell Dev Biol Anim. 2005 Nov-Dec; 41(10):349-55.
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Ravnic DJ, Jiang X, Wolloscheck T, Pratt JP, Huss H, Mentzer SJ, Konerding MA. Vessel painting of the microcirculation using fluorescent lipophilic tracers. Microvasc Res. 2005 Jul; 70(1-2):90-6.
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Ingenito EP, Tsai LW, Mentzer SJ, Jaklitsch MT, Reilly JJ, Lutchen K, Mazan M, Hoffman A. Respiratory impedance following bronchoscopic or surgical lung volume reduction for emphysema. Respiration. 2005 Jul-Aug; 72(4):406-17.
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Linden PA, Bueno R, Colson YL, Jaklitsch MT, Lukanich J, Mentzer S, Sugarbaker DJ. Lung resection in patients with preoperative FEV1 < 35% predicted. Chest. 2005 Jun; 127(6):1984-90.
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Mentzer SJ. Surgical palliative care in thoracic diseases. Surg Clin North Am. 2005 Apr; 85(2):315-28.
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Mamon HJ, Yeap BY, Jänne PA, Reblando J, Shrager S, Jaklitsch MT, Mentzer S, Lukanich JM, Sugarbaker DJ, Baldini EH, Berman S, Skarin A, Bueno R. High risk of brain metastases in surgically staged IIIA non-small-cell lung cancer patients treated with surgery, chemotherapy, and radiation. J Clin Oncol. 2005 Mar 01; 23(7):1530-7.
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Sugarbaker DJ, Jaklitsch MT, Bueno R, Richards W, Lukanich J, Mentzer SJ, Colson Y, Linden P, Chang M, Capalbo L, Oldread E, Neragi-Miandoab S, Swanson SJ, Zellos LS. Prevention, early detection, and management of complications after 328 consecutive extrapleural pneumonectomies. J Thorac Cardiovasc Surg. 2004 Jul; 128(1):138-46.
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Mery CM, Pappas AN, Bueno R, Mentzer SJ, Lukanich JM, Sugarbaker DJ, Jaklitsch MT. Relationship between a history of antecedent cancer and the probability of malignancy for a solitary pulmonary nodule. Chest. 2004 Jun; 125(6):2175-81.
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Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S, Tanabe K, Duda R, Mentzer S, Jaklitsch M, Bueno R, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Mihm M, Dranoff G. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. J Clin Oncol. 2003 Sep 01; 21(17):3343-50.
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Secomb TW, Konerding MA, West CA, Su M, Young AJ, Mentzer SJ. Microangiectasias: structural regulators of lymphocyte transmigration. Proc Natl Acad Sci U S A. 2003 Jun 10; 100(12):7231-4.
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Moy ML, Mentzer SJ, Reilly JJ. Ambulatory monitoring of cumulative free-living activity. IEEE Eng Med Biol Mag. 2003 May-Jun; 22(3):89-95.
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Colwell AS, Mentzer SJ, Vargas SO, Orgill DP. The role of muscle flaps in pulmonary aspergillosis. Plast Reconstr Surg. 2003 Mar; 111(3):1147-50.
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Salgia R, Lynch T, Skarin A, Lucca J, Lynch C, Jung K, Hodi FS, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, Wain J, Mathisen D, Wright C, Fidias P, Donahue D, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Sugarbaker D, Mihm M, Dranoff G. Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma. J Clin Oncol. 2003 Feb 15; 21(4):624-30.
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Kim EY, Zeng QT, Kuo FC, Rawn J, Mentzer SJ. Visual representation of cell subpopulation from flow cytometry data. AMIA Annu Symp Proc. 2003; 893.
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Su M, West CA, Young AJ, He C, Konerding MA, Mentzer SJ. Dynamic deformation of migratory efferent lymph-derived cells "trapped" in the inflammatory microcirculation. J Cell Physiol. 2003 Jan; 194(1):54-62.
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West CA, He C, Young AJ, Su M, Zhao T, Swanson SJ, Mentzer SJ. Spatial variation of plasma flow in the oxazolone-stimulated microcirculation. Inflamm Res. 2002 Dec; 51(12):572-8.
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Ingenito EP, Loring SH, Moy ML, Mentzer SJ, Swanson SJ, Reilly JJ. Physiological characterization of variability in response to lung volume reduction surgery. J Appl Physiol (1985). 2003 Jan; 94(1):20-30.
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He C, Young AJ, West CA, Su M, Konerding MA, Mentzer SJ. Stimulation of regional lymphatic and blood flow by epicutaneous oxazolone. J Appl Physiol (1985). 2002 Sep; 93(3):966-73.
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Zeng Q, Wand M, Young AJ, Rawn J, Milford EL, Mentzer SJ, Greenes RA. Matching of flow-cytometry histograms using information theory in feature space. Proc AMIA Symp. 2002; 929-33.
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West CA, Fischer GA, Young AJ, He C, Su M, Mentzer SJ. Biochemical changes in the efferent lymph plasma after oxazolone stimulation. Dev Comp Immunol. 2002 Jan; 26(1):111-9.
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Esnaola NF, Lazarides SN, Mentzer SJ, Kuntz KM. Outcomes and cost-effectiveness of alternative staging strategies for non-small-cell lung cancer. J Clin Oncol. 2002 Jan 01; 20(1):263-73.
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Kim EY, Zeng Q, Rawn J, Wand M, Young AJ, Milford E, Mentzer SJ, Greenes RA. Using a neural network with flow cytometry histograms to recognize cell surface protein binding patterns. Proc AMIA Symp. 2002; 380-4.
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Swanson SJ, Batirel HF, Bueno R, Jaklitsch MT, Lukanich JM, Allred E, Mentzer SJ, Sugarbaker DJ. Transthoracic esophagectomy with radical mediastinal and abdominal lymph node dissection and cervical esophagogastrostomy for esophageal carcinoma. Ann Thorac Surg. 2001 Dec; 72(6):1918-24; discussion 1924-5.
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Li X, Su M, West CA, He C, Swanso SJ, Secomb TW, Mentzer SJ. Effect of shear stress on efferent lymph-derived lymphocytes in contact with activated endothelial monolayers. In Vitro Cell Dev Biol Anim. 2001 Oct; 37(9):599-605.
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West CA, He C, Su M, Secomb TW, Konerding MA, Young AJ, Mentzer SJ. Focal topographic changes in inflammatory microcirculation associated with lymphocyte slowing and transmigration. Am J Physiol Heart Circ Physiol. 2001 Oct; 281(4):H1742-50.
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Mentzer SJ, Perrine SP, Faller DV. Epstein--Barr virus post-transplant lymphoproliferative disease and virus-specific therapy: pharmacological re-activation of viral target genes with arginine butyrate. Transpl Infect Dis. 2001 Sep; 3(3):177-85.
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Faller DV, Mentzer SJ, Perrine SP. Induction of the Epstein-Barr virus thymidine kinase gene with concomitant nucleoside antivirals as a therapeutic strategy for Epstein-Barr virus-associated malignancies. Curr Opin Oncol. 2001 Sep; 13(5):360-7.
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Bueno R, Swanson SJ, Jaklitsch MT, Lukanich JM, Mentzer SJ, Sugarbaker DJ. Combined antegrade and retrograde dilation: a new endoscopic technique in the management of complex esophageal obstruction. Gastrointest Endosc. 2001 Sep; 54(3):368-72.
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Su M, Young AJ, He C, West CA, Swanson SJ, Mentzer SJ. Biphasic response of the regional lymphatics in the normal lymphocyte transfer reaction. Transplantation. 2001 Aug 15; 72(3):516-22.
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Ingenito EP, Reilly JJ, Mentzer SJ, Swanson SJ, Vin R, Keuhn H, Berger RL, Hoffman A. Bronchoscopic volume reduction: a safe and effective alternative to surgical therapy for emphysema. Am J Respir Crit Care Med. 2001 Jul 15; 164(2):295-301.
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Su M, He C, West CA, Mentzer SJ. Cytolytic peptides induce biphasic permeability changes in mammalian cell membranes. J Immunol Methods. 2001 Jun 01; 252(1-2):63-71.
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Zhao T, He C, Su M, West CA, Swanson SJ, Young AJ, Mentzer SJ. Cell adhesion molecule expression in the sheep thymus. Dev Comp Immunol. 2001 Jun-Jul; 25(5-6):519-30.
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Kaczka DW, Ingenito EP, Body SC, Duffy SE, Mentzer SJ, DeCamp MM, Lutchen KR. Inspiratory lung impedance in COPD: effects of PEEP and immediate impact of lung volume reduction surgery. J Appl Physiol (1985). 2001 May; 90(5):1833-41.
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Jaklitsch MT, Mery CM, Lukanich JM, Richards WG, Bueno R, Swanson SJ, Mentzer SJ, Davis BD, Allred EN, Sugarbaker DJ. Sequential thoracic metastasectomy prolongs survival by re-establishing local control within the chest. J Thorac Cardiovasc Surg. 2001 Apr; 121(4):657-67.
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Ingenito EP, Loring SH, Moy ML, Mentzer SJ, Swanson SJ, Hunsaker A, McKee CC, Reilly JJ. Comparison of physiological and radiological screening for lung volume reduction surgery. Am J Respir Crit Care Med. 2001 Apr; 163(5):1068-73.
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West CA, He C, Su M, Swanson SJ, Mentzer SJ. Aldehyde fixation of thiol-reactive fluorescent cytoplasmic probes for tracking cell migration. J Histochem Cytochem. 2001 Apr; 49(4):511-8.
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Ingenito EP, Loring SH, Moy ML, Mentzer SJ, Swanson SJ, Reilly JJ. Interpreting improvement in expiratory flows after lung volume reduction surgery in terms of flow limitation theory. Am J Respir Crit Care Med. 2001 Apr; 163(5):1074-80.
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West CA, He C, Su M, Rawn J, Swanson S, Hay JB, Mentzer SJ. Stochastic regulation of cell migration from the efferent lymph to oxazolone-stimulated skin. J Immunol. 2001 Feb 01; 166(3):1517-23.
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Breathnach OS, Kwiatkowski DJ, Finkelstein DM, Godleski J, Sugarbaker DJ, Johnson BE, Mentzer S. Bronchioloalveolar carcinoma of the lung: recurrences and survival in patients with stage I disease. J Thorac Cardiovasc Surg. 2001 Jan; 121(1):42-7.
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Zeng Q, Young AJ, Boxwala A, Rawn J, Long W, Wand M, Salganik M, Milford EL, Mentzer SJ, Greenes RA. Molecular identification using flow cytometry histograms and information theory. Proc AMIA Symp. 2001; 776-80.
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Bueno R, Richards WG, Swanson SJ, Jaklitsch MT, Lukanich JM, Mentzer SJ, Sugarbaker DJ. Nodal stage after induction therapy for stage IIIA lung cancer determines patient survival. Ann Thorac Surg. 2000 Dec; 70(6):1826-31.
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Rawn J, DeCamp MM, Swanson SJ, Warner A, Warren H, Mentzer SJ. Angiocentric recruitment of lymphocytes into the lung after the intrabronchial instillation of antigen. Exp Lung Res. 2000 Mar; 26(2):89-103.
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Su M, He C, West CA, Mentzer SJ. Generation of sheep X (sheep X mouse) heterohybridoma cell line expressing the beta-1 integrin membrane molecule. Hybridoma. 2000 Feb; 19(1):81-7.
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Swanson SJ, Mentzer SJ, Reilly JJ, Bueno R, Lukanich JM, Jaklitsch MT, Kobzik L, Ingenito EP, Fuhlbrigge A, Donovan C, McKee C, Boyle K, Fagan GP, Sugarbaker DJ. Surveillance transbronchial lung biopsies: implication for survival after lung transplantation. J Thorac Cardiovasc Surg. 2000 Jan; 119(1):27-37.
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Mentzer SJ. Dendritic cells in the pathophysiology of sarcoidal reactions. In Vivo. 2000 Jan-Feb; 14(1):209-12.
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Mentzer SJ, Swanson SJ. Treatment of patients with lung cancer and severe emphysema. Chest. 1999 Dec; 116(6 Suppl):477S-479S.
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Jaklitsch MT, Bueno R, Swanson SJ, Mentzer SJ, Lukanich JM, Sugarbaker DJ. New surgical options for elderly lung cancer patients. Chest. 1999 Dec; 116(6 Suppl):480S-485S.
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Swanson SJ, Jaklitsch MT, Mentzer SJ, Bueno R, Lukanich JM, Sugarbaker DJ. Management of the solitary pulmonary nodule: role of thoracoscopy in diagnosis and therapy. Chest. 1999 Dec; 116(6 Suppl):523S-524S.
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Moy ML, Loring SH, Ingenito EP, Mentzer SJ, Reilly JJ. Causes of allograft dysfunction after single lung transplantation for emphysema: extrinsic restriction versus intrinsic obstruction. Brigham and Women's Hospital Lung Transplantation Group. J Heart Lung Transplant. 1999 Oct; 18(10):986-93.
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Loring SH, Leith DE, Connolly MJ, Ingenito EP, Mentzer SJ, Reilly JJ. Model of functional restriction in chronic obstructive pulmonary disease, transplantation, and lung reduction surgery. Am J Respir Crit Care Med. 1999 Sep; 160(3):821-8.
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Mallery S, DeCamp M, Bueno R, Mentzer SJ, Sugarbaker DJ, Swanson SJ, Van Dam J. Pretreatment staging by endoscopic ultrasonography does not predict complete response to neoadjuvant chemoradiation in patients with esophageal carcinoma. Cancer. 1999 Sep 01; 86(5):764-9.
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Baldini EH, DeCamp MM, Katz MS, Berman SM, Swanson SJ, Mentzer SJ, Bueno R, Sugarbaker DJ. Patterns of recurrence and outcome for patients with clinical stage II non-small-cell lung cancer. Am J Clin Oncol. 1999 Feb; 22(1):8-14.
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Moy ML, Ingenito EP, Mentzer SJ, Evans RB, Reilly JJ. Health-related quality of life improves following pulmonary rehabilitation and lung volume reduction surgery. Chest. 1999 Feb; 115(2):383-9.
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Sugarbaker DJ, Flores RM, Jaklitsch MT, Richards WG, Strauss GM, Corson JM, DeCamp MM, Swanson SJ, Bueno R, Lukanich JM, Baldini EH, Mentzer SJ. Resection margins, extrapleural nodal status, and cell type determine postoperative long-term survival in trimodality therapy of malignant pleural mesothelioma: results in 183 patients. J Thorac Cardiovasc Surg. 1999 Jan; 117(1):54-63; discussion 63-5.
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Soiffer R, Lynch T, Mihm M, Jung K, Rhuda C, Schmollinger JC, Hodi FS, Liebster L, Lam P, Mentzer S, Singer S, Tanabe KK, Cosimi AB, Duda R, Sober A, Bhan A, Daley J, Neuberg D, Parry G, Rokovich J, Richards L, Drayer J, Berns A, Clift S, Cohen LK, Mulligan RC, Dranoff G. Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma. Proc Natl Acad Sci U S A. 1998 Oct 27; 95(22):13141-6.
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Haley KJ, Sunday ME, Wiggs BR, Kozakewich HP, Reilly JJ, Mentzer SJ, Sugarbaker DJ, Doerschuk CM, Drazen JM. Inflammatory cell distribution within and along asthmatic airways. Am J Respir Crit Care Med. 1998 Aug; 158(2):565-72.
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Mentzer SJ, Fingeroth J, Reilly JJ, Perrine SP, Faller DV. Arginine butyrate-induced susceptibility to ganciclovir in an Epstein-Barr-virus-associated lymphoma. Blood Cells Mol Dis. 1998 Jun; 24(2):114-23.
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Silverman EK, Chapman HA, Drazen JM, Weiss ST, Rosner B, Campbell EJ, O'DONNELL WJ, Reilly JJ, Ginns L, Mentzer S, Wain J, Speizer FE. Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis. Am J Respir Crit Care Med. 1998 Jun; 157(6 Pt 1):1770-8.
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Ingenito EP, Evans RB, Loring SH, Kaczka DW, Rodenhouse JD, Body SC, Sugarbaker DJ, Mentzer SJ, DeCamp MM, Reilly JJ. Relation between preoperative inspiratory lung resistance and the outcome of lung-volume-reduction surgery for emphysema. N Engl J Med. 1998 Apr 23; 338(17):1181-5.
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Monson JM, Stark P, Reilly JJ, Sugarbaker DJ, Strauss GM, Swanson SJ, Decamp MM, Mentzer SJ, Baldini EH. Clinical radiation pneumonitis and radiographic changes after thoracic radiation therapy for lung carcinoma. Cancer. 1998 Mar 01; 82(5):842-50.
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Mentzer SJ, Swanson SJ, DeCamp MM, Bueno R, Sugarbaker DJ. Mediastinoscopy, thoracoscopy, and video-assisted thoracic surgery in the diagnosis and staging of lung cancer. Chest. 1997 Oct; 112(4 Suppl):239S-241S.
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DeCamp MM, Mentzer SJ, Swanson SJ, Sugarbaker DJ. Malignant effusive disease of the pleura and pericardium. Chest. 1997 Oct; 112(4 Suppl):291S-295S.
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Swanson SJ, Mentzer SJ, DeCamp MM, Bueno R, Richards WG, Ingenito EP, Reilly JJ, Sugarbaker DJ. No-cut thoracoscopic lung plication: a new technique for lung volume reduction surgery. J Am Coll Surg. 1997 Jul; 185(1):25-32.
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Mentzer SJ. Mediastinoscopy, thoracoscopy, and video-assisted thoracic surgery in the diagnosis and staging of lung cancer. Hematol Oncol Clin North Am. 1997 Jun; 11(3):435-47.
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Elias AD, Skarin AT, Leong T, Mentzer S, Strauss G, Lynch T, Shulman L, Jacobs C, Abner A, Baldini EH, Frei E, Sugarbaker DJ. Neoadjuvant therapy for surgically staged IIIA N2 non-small cell lung cancer (NSCLC). Lung Cancer. 1997 May; 17(1):147-61.
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Baldini EH, Recht A, Strauss GM, DeCamp MM, Swanson SJ, Liptay MJ, Mentzer SJ, Sugarbaker DJ. Patterns of failure after trimodality therapy for malignant pleural mesothelioma. Ann Thorac Surg. 1997 Feb; 63(2):334-8.
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Dranoff G, Soiffer R, Lynch T, Mihm M, Jung K, Kolesar K, Liebster L, Lam P, Duda R, Mentzer S, Singer S, Tanabe K, Johnson R, Sober A, Bhan A, Clift S, Cohen L, Parry G, Rokovich J, Richards L, Drayer J, Berns A, Mulligan RC. A phase I study of vaccination with autologous, irradiated melanoma cells engineered to secrete human granulocyte-macrophage colony stimulating factor. Hum Gene Ther. 1997 Jan 01; 8(1):111-23.
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Jaklitsch MT, DeCamp MM, Liptay MJ, Harpole DH, Swanson SJ, Mentzer SJ, Sugarbaker DJ. Video-assisted thoracic surgery in the elderly. A review of 307 cases. Chest. 1996 Sep; 110(3):751-8.
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Sugarbaker DJ, Garcia JP, Richards WG, Harpole DH, Healy-Baldini E, DeCamp MM, Mentzer SJ, Liptay MJ, Strauss GM, Swanson SJ. Extrapleural pneumonectomy in the multimodality therapy of malignant pleural mesothelioma. Results in 120 consecutive patients. Ann Surg. 1996 Sep; 224(3):288-94; discussion 294-6.
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Hunsaker AR, Munden RF, Pugatch RD, Mentzer SJ. Sarcoidlike reaction in patients with malignancy. Radiology. 1996 Jul; 200(1):255-61.
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Mentzer SJ, Longtine J, Fingeroth J, Reilly JJ, DeCamp MM, O'Donnell W, Swanson SJ, Faller DV, Sugarbaker DJ. Immunoblastic lymphoma of donor origin in the allograft after lung transplantation. Transplantation. 1996 Jun 27; 61(12):1720-5.
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Birmingham B, Mentzer SJ, Body SC. Laryngeal mask airway for therapeutic fiberoptic bronchoscopic procedures. J Cardiothorac Vasc Anesth. 1996 Jun; 10(4):519-20.
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Harpole DH, Healey EA, DeCamp MM, Mentzer SJ, Strauss GM, Sugarbaker DJ. Chest wall invasive non-small cell lung cancer: patterns of failure and implications for a revised staging system. Ann Surg Oncol. 1996 May; 3(3):261-9.
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Li X, Abdi K, Rawn J, Mackay CR, Mentzer SJ. LFA-1 and L-selectin regulation of recirculating lymphocyte tethering and rolling on lung microvascular endothelium. Am J Respir Cell Mol Biol. 1996 Apr; 14(4):398-406.
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Harpole DH, Liptay MJ, DeCamp MM, Mentzer SJ, Swanson SJ, Sugarbaker DJ. Prospective analysis of pneumonectomy: risk factors for major morbidity and cardiac dysrhythmias. Ann Thorac Surg. 1996 Mar; 61(3):977-82.
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Li X, Rawn J, DeCamp MM, Mentzer SJ. Hybridoma screening for cell adhesion molecules using multiple parallel comparisons in conditions of flow. Hybridoma. 1996 Feb; 15(1):43-7.
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Lynch T, Kalish L, Mentzer S, Decamp M, Strauss G, Sugarbaker D. Optimal therapy of malignant pleural effusions. Int J Oncol. 1996 Jan; 8(1):183-90.
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DeCamp MM, Jaklitsch MT, Mentzer SJ, Harpole DH, Sugarbaker DJ. The safety and versatility of video-thoracoscopy: a prospective analysis of 895 consecutive cases. J Am Coll Surg. 1995 Aug; 181(2):113-20.
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Ginis I, Mentzer SJ, Li X, Faller DV. Characterization of a hypoxia-responsive adhesion molecule for leukocytes on human endothelial cells. J Immunol. 1995 Jul 15; 155(2):802-10.
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Mentzer SJ, DeCamp MM, Harpole DH, Sugarbaker DJ. Thoracoscopy and video-assisted thoracic surgery in the treatment of lung cancer. Chest. 1995 Jun; 107(6 Suppl):298S-301S.
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Abdi K, Rogers RA, Li X, Lopez P, Rawn J, Mentzer SJ. In situ fluorescence labeling of sheep lung microvascular endothelium. In Vitro Cell Dev Biol Anim. 1995 Apr; 31(4):310-5.
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Abdi K, Kobzik L, Li X, Mentzer SJ. Expression of membrane glycoconjugates on sheep lung endothelium. Lab Invest. 1995 Apr; 72(4):445-52.
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Fletcher JA, Longtine J, Wallace K, Mentzer SJ, Sugarbaker DJ. Cytogenetic and histologic findings in 17 pulmonary chondroid hamartomas: evidence for a pathogenetic relationship with lipomas and leiomyomas. Genes Chromosomes Cancer. 1995 Mar; 12(3):220-3.
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Mentzer SJ, Reilly JJ, DeCamp M, Sugarbaker DJ, Faller DV. Potential mechanism of vasomotor dysregulation after lung transplantation for primary pulmonary hypertension. J Heart Lung Transplant. 1995 Mar-Apr; 14(2):387-93.
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Mentzer SJ. Immunoreactivity in lung cancer. Chest Surg Clin N Am. 1995 Feb; 5(1):57-71.
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Li X, Abdi K, Mentzer SJ. Hybridoma screening using an amplified fluorescence microassay to quantify immunoglobulin concentration. Hybridoma. 1995 Feb; 14(1):75-8.
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Mentzer SJ, Aranki SF, Reilly JJ, DeCamp MM, Hartigan P, O'Donnell W, Sugarbaker DJ. Single-lung transplantation in situs inversus. Ann Thorac Surg. 1994 Oct; 58(4):1176-8.
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Abdi K, Kobzik L, Li X, Mentzer SJ. Membrane glycoconjugates expressed on sheep airway epithelium. J Histochem Cytochem. 1994 Oct; 42(10):1341-7.
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Li X, Abdi K, Herren T, Faller DV, Mentzer SJ. Affinity membrane identification of immunoglobulin subclass in hybridoma screening. Hybridoma. 1994 Oct; 13(5):431-5.
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Li X, Abdi K, Mentzer SJ. o-phthaldehyde fluorescence microassay for the determination of antibody concentration. J Immunol Methods. 1994 Jun 24; 172(2):141-5.
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Herman SJ, Winton TL, Weisbrod GL, Towers MJ, Mentzer SJ. Mediastinal invasion by bronchogenic carcinoma: CT signs. Radiology. 1994 Mar; 190(3):841-6.
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Mentzer SJ, Reilly JJ, Caplan AL, Sugarbaker DJ. Ethical considerations in lung retransplantation. J Heart Lung Transplant. 1994 Jan-Feb; 13(1 Pt 1):56-8.
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Ginis I, Mentzer SJ, Faller DV. Oxygen tension regulates neutrophil adhesion to human endothelial cells via an LFA-1-dependent mechanism. J Cell Physiol. 1993 Dec; 157(3):569-78.
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Kirn DH, Lynch TJ, Mentzer SJ, Lee TH, Strauss GM, Elias AD, Skarin AT, Sugarbaker DJ. Multimodality therapy of patients with stage IIIA, N2 non-small-cell lung cancer. Impact of preoperative chemotherapy on resectability and downstaging. J Thorac Cardiovasc Surg. 1993 Oct; 106(4):696-702.
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Sugarbaker DJ, Strauss GM, Lynch TJ, Richards W, Mentzer SJ, Lee TH, Corson JM, Antman KH. Node status has prognostic significance in the multimodality therapy of diffuse, malignant mesothelioma. J Clin Oncol. 1993 Jun; 11(6):1172-8.
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Axford TC, Clair DG, Bertagnolli MM, Mentzer SJ, Sugarbaker DJ. Staged antrectomy and thoracoscopic truncal vagotomy for perforated peptic ulcer disease. Ann Thorac Surg. 1993 Jun; 55(6):1571-3.
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Mentzer SJ, Antman KH, Attinger C, Shemin R, Corson JM, Sugarbaker DJ. Selected benefits of thoracotomy and chemotherapy for sarcoma metastatic to the lung. J Surg Oncol. 1993 May; 53(1):54-9.
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Mentzer SJ, Reilly JJ, Skarin AT, Sugarbaker DJ. Patterns of lung involvement by malignant lymphoma. Surgery. 1993 May; 113(5):507-14.
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Mentzer SJ, Myers DW, Sugarbaker DJ. Sleeve lobectomy, segmentectomy, and thoracoscopy in the management of carcinoma of the lung. Chest. 1993 Apr; 103(4 Suppl):415S-417S.
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Mentzer SJ, Reilly JJ, Sugarbaker DJ. Surgical resection in the management of small-cell carcinoma of the lung. Chest. 1993 Apr; 103(4 Suppl):349S-351S.
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Reilly JJ, Mentzer SJ, Sugarbaker DJ. Preoperative assessment of patients undergoing pulmonary resection. Chest. 1993 Apr; 103(4 Suppl):342S-345S.
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Sugarbaker DJ, Mentzer SJ, DeCamp M, Lynch TJ, Strauss GM. Extrapleural pneumonectomy in the setting of a multimodality approach to malignant mesothelioma. Chest. 1993 Apr; 103(4 Suppl):377S-381S.
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Ginis I, Mentzer SJ, Faller DV. Hypoxia induces lymphocyte adhesion to human mesenchymal cells via an LFA-1-dependent mechanism. Am J Physiol. 1993 Mar; 264(3 Pt 1):C617-24.
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Abdi K, Li X, Mentzer SJ. Semi-dry PhastTransfer detection of biotinylated cell surface molecules. Electrophoresis. 1993 Jan-Feb; 14(1-2):73-7.
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Fletcher JA, Pinkus GS, Donovan K, Naeem R, Sugarbaker DJ, Mentzer S, Pinkus JL, Longtine J. Clonal rearrangement of chromosome band 6p21 in the mesenchymal component of pulmonary chondroid hamartoma. Cancer Res. 1992 Nov 15; 52(22):6224-8.
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Mentzer SJ, Filler RM, Phillips J. Limited pulmonary resections for congenital cystic adenomatoid malformation of the lung. J Pediatr Surg. 1992 Nov; 27(11):1410-3.
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Sugarbaker DJ, Mentzer SJ, Strauss G. Extrapleural pneumonectomy in the treatment of malignant pleural mesothelioma. Ann Thorac Surg. 1992 Nov; 54(5):941-6.
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Li X, Abdi K, Mentzer SJ. Cloning hybridomas in a reversible three-dimensional alginate matrix. Hybridoma. 1992 Oct; 11(5):645-52.
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Sugarbaker DJ, Mentzer SJ. Improved technique for hilar vascular stapling. Ann Thorac Surg. 1992 Jan; 53(1):165-6.
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Sugarbaker DJ, Heher EC, Lee TH, Couper G, Mentzer S, Corson JM, Collins JJ, Shemin R, Pugatch R, Weissman L, et al. Extrapleural pneumonectomy, chemotherapy, and radiotherapy in the treatment of diffuse malignant pleural mesothelioma. J Thorac Cardiovasc Surg. 1991 Jul; 102(1):10-4; discussion 14-5.
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Maziarz RT, Mentzer SJ, Burakoff SJ, Faller DV. Distinct effects of interferon-gamma and MHC class I surface antigen levels on resistance of the K562 tumor cell line to natural killer-mediated lysis. Cell Immunol. 1990 Oct 15; 130(2):329-38.
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Mentzer SJ, Faller DV. Soluble and surface-bound immunoglobulin triggers human monocyte activation and hydrogen peroxide release. Exp Hematol. 1990 Aug; 18(7):812-7.
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Mentzer SJ, Burakoff SJ, Barbosa JA. Induction of HLA class I surface expression recruits low-affinity cytolytic T lymphocytes. Int Arch Allergy Appl Immunol. 1990; 91(4):437-40.
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Santos-Aguado J, Crimmins MA, Mentzer SJ, Burakoff SJ, Strominger JL. Alloreactivity studied with mutants of HLA-A2. Proc Natl Acad Sci U S A. 1989 Nov; 86(22):8936-40.
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Abdi K, Reed ML, Mentzer SJ, Herrmann SH. Temperature requirements and kinetics of T cell signaling. Velocity of triggering correlates with functional effects of anti-CD3 mAb. J Immunol. 1989 May 01; 142(9):2971-80.
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Mentzer SJ, Crimmins MA, Herrmann SH. Functional domains of the CD11a adhesion molecule in lymphokine activated killer (LAK)-mediated cytolysis. J Clin Lab Immunol. 1988 Dec; 27(4):155-61.
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Mentzer SJ, Wilson RE, Burakoff SJ, Herrmann SH. Membrane-bound anti-CD3 monoclonal antibodies trigger cytolytic T-lymphocyte-mediated tumor lysis. Arch Surg. 1988 Oct; 123(10):1280-5.
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Sieff CA, Niemeyer CM, Mentzer SJ, Faller DV. Interleukin-1, tumor necrosis factor, and the production of colony-stimulating factors by cultured mesenchymal cells. Blood. 1988 Oct; 72(4):1316-23.
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Mentzer SJ, Rothlein R, Springer TA, Faller DV. Intercellular adhesion molecule-1 (ICAM-1) is involved in the cytolytic T lymphocyte interaction with a human synovial cell line. J Cell Physiol. 1988 Oct; 137(1):173-8.
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Faller DV, Crimmins MA, Mentzer SJ. Human T-cell leukemia virus type I infection of CD4+ or CD8+ cytotoxic T-cell clones results in immortalization with retention of antigen specificity. J Virol. 1988 Aug; 62(8):2942-50.
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Mentzer SJ, Herrmann SH, Crimmins MA, Burakoff SJ, Faller DV. The role of CD18 in phorbol ester-induced human monocyte-mediated cytotoxicity. Cell Immunol. 1988 Aug; 115(1):66-77.
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Mentzer SJ, Osteen RT, Pappas TN, Rosenthal DS, Canellos GP, Wilson RE. Surgical therapy of localized abdominal non-Hodgkin's lymphomas. Surgery. 1988 Jun; 103(6):609-14.
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Barbosa JA, Santos-Aguado J, Mentzer SJ, Strominger JL, Burakoff SJ, Biro PA. Site-directed mutagenesis of class I HLA genes. Role of glycosylation in surface expression and functional recognition. J Exp Med. 1987 Nov 01; 166(5):1329-50.
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Mentzer SJ, Remold-O'Donnell E, Crimmins MA, Bierer BE, Rosen FS, Burakoff SJ. Sialophorin, a surface sialoglycoprotein defective in the Wiskott-Aldrich syndrome, is involved in human T lymphocyte proliferation. J Exp Med. 1987 May 01; 165(5):1383-92.
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Mentzer SJ, Smith BR, Barbosa JA, Crimmins MA, Herrmann SH, Burakoff SJ. CTL adhesion and antigen recognition are discrete steps in the human CTL-target cell interaction. J Immunol. 1987 Mar 01; 138(5):1325-30.
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Mentzer SJ, Crimmins MA, Burakoff SJ, Faller DV. Alpha and beta subunits of the LFA-1 membrane molecule are involved in human monocyte-endothelial cell adhesion. J Cell Physiol. 1987 Mar; 130(3):410-5.
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Mentzer SJ, Osteen RT, Starnes HF, Moloney WC, Rosenthal D, Canellos G, Wilson RE. Splenic enlargement and hyperfunction as indications for splenectomy in chronic leukemia. Ann Surg. 1987 Jan; 205(1):13-7.
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Mentzer SJ, Osteen RT, Wilson RE. Local recurrence and the deep resection margin in carcinoma of the breast. Surg Gynecol Obstet. 1986 Dec; 163(6):513-7.
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Mentzer SJ, Bierer BE, Anderson DC, Springer TA, Burakoff SJ. Abnormal cytolytic activity of lymphocyte function-associated antigen-1-deficient human cytolytic T lymphocyte clones. J Clin Invest. 1986 Nov; 78(5):1387-91.
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Mentzer SJ, Krensky AM, Burakoff SJ. Mapping functional epitopes of the human LFA-1 glycoprotein: monoclonal antibody inhibition of NK and CTL effectors. Hum Immunol. 1986 Nov; 17(3):288-96.
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Mentzer SJ, Guyre PM, Burakoff SJ, Faller DV. Spontaneous aggregation as a mechanism for human monocyte purification. Cell Immunol. 1986 Sep; 101(2):312-9.
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Mentzer SJ, Barbosa JA, Strominger JL, Biro PA, Burakoff SJ. Species-restricted recognition of transfected HLA-A2 and HLA-B7 by human CTL clones. J Immunol. 1986 Jul 15; 137(2):408-13.
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Mentzer SJ, Faller DV, Burakoff SJ. Interferon-gamma induction of LFA-1-mediated homotypic adhesion of human monocytes. J Immunol. 1986 Jul 01; 137(1):108-13.
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Barbosa JA, Mentzer SJ, Kamarck ME, Hart J, Biro PA, Strominger JL, Burakoff SJ. Gene mapping and somatic cell hybrid analysis of the role of human lymphocyte function-associated antigen-3 (LFA-3) in CTL-target cell interactions. J Immunol. 1986 Apr 15; 136(8):3085-91.
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Mentzer SJ, Burakoff SJ, Faller DV. Adhesion of T lymphocytes to human endothelial cells is regulated by the LFA-1 membrane molecule. J Cell Physiol. 1986 Feb; 126(2):285-90.
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Starnes HF, Moore FD, Mentzer S, Osteen RT, Steele GD, Wilson RE. Abdominal pain in neutropenic cancer patients. Cancer. 1986 Feb 01; 57(3):616-21.
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Bierer BE, Mentzer SJ, Greenstein JL, Burakoff SJ. The role of functional cell surface antigens in T cell activation. Year Immunol. 1986; 2:39-59.
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Krensky AM, Mentzer SJ, Clayberger C, Anderson DC, Schmalstieg FC, Burakoff SJ, Springer TA. Heritable lymphocyte function-associated antigen-1 deficiency: abnormalities of cytotoxicity and proliferation associated with abnormal expression of LFA-1. J Immunol. 1985 Nov; 135(5):3102-8.
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Mentzer SJ, Fryd DS, Kjellstrand CM. Why do patients with postsurgical acute tubular necrosis die? Arch Surg. 1985 Aug; 120(8):907-10.
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Mentzer SJ, Barbosa JA, Burakoff SJ. T3 monoclonal antibody activation of nonspecific cytolysis: a mechanism of CTL inhibition. J Immunol. 1985 Jul; 135(1):34-8.
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Mentzer SJ, Gromkowski SH, Krensky AM, Burakoff SJ, Martz E. LFA-1 membrane molecule in the regulation of homotypic adhesions of human B lymphocytes. J Immunol. 1985 Jul; 135(1):9-11.
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Barbosa JA, Mentzer SJ, Minowada G, Strominger JL, Burakoff SJ, Biro PA. Recognition of HLA-A2 and -B7 antigens by cloned cytotoxic T lymphocytes after gene transfer into human and monkey, but not mouse, cells. Proc Natl Acad Sci U S A. 1984 Dec; 81(23):7549-53.
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Mentzer S, Osteen RT, Steele G. Surgical implications for infusion chemotherapy. Cancer. 1984 Dec 01; 54(11 Suppl):2618-26.
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Mentzer SJ, Sugarbaker PH. Adductor muscle group excision. Surgery. 1982 Jun; 91(6):662-8.
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Vallera DA, Mentzer SJ, Maizel SE. Tumor sponge implantation: an in vivo method for studying syngeneic, primary antitumor lymphocyte responses. Cancer Res. 1982 Feb; 42(2):397-404.
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Maizel SE, Vallera DA, Mentzer SJ, Ferguson RM. The relative immunogenicity of murine tissues in vivo. Curr Surg. 1980 Nov-Dec; 37(6):435-8.
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Snyder ML, Kleck RE, Strenta A, Mentzer SJ. Avoidance of the handicapped: an attributional ambiguity analysis. J Pers Soc Psychol. 1979 Dec; 37(12):2297-306.
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