Barr Researchers
Miyako Abe, PhD (1994)
Research Associate in Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, D710B
Boston, MA 02115
Phone: (617) 632-5088
E-mail: miyako_abe@dfci.harvard.edu
Current Research Interests:
My research is focused on studies of the role of CAG repeats within the androgen receptor gene, which encodes the poly-glutamine chain, in transcriptional regulation mediated via the androgen receptor in prostate cancers. Also, I am investigating biomarkers and/or genetic mutations that will yield more information for further understanding the development of prostate cancers, and for helping furthe to develop strategies for curing such prostate cancers.
Koichi Akashi, MD, PhD (2000)
Assistant Professor of Pathology
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street, SM770A
Boston, MA 02115
Phone: (617) 632-3595
Fax: (617) 632-3809
E-mail: koichi_akashi@dfci.harvard.edu
Current Research Interests:
Hematopoietic stem cells choose either a lymphoid or myeloid lineage pathway at an early stage of differentiation. We recently identified and purified the earliest progenitors on each pathway in mouse bone marrow - the common lymphoid progenitors and the common myeloid progenitors. Using these highly purified progenitor populations as well as hematopoietic stem cells, we are attempting to identify genes involved in hematopoietic lineage commitment.
Honors/Awards:
New Investigator Award: Leukemia Research Foundation, 2001
Damon Runyon-Walter Winchell Cancer Research Scholar Award, 2001
Cheryl Whitlock/Pathology Memorial Prize, 2000
Michael Brenner, MD (1989)
Theodore B. Bayles Professor of Medicine
Harvard Medical School
Chief Division of Rheumatology, Immunology and Allergy
Brigham and Women's Hospital
44 Binney Street, SM552
Boston, MA 02115
Phone: (617) 525-1000
Fax: (617) 525-1001
E-mail: mbrenner@rics.bwh.harvard.edu
Current Research Interests:
My research involves the function of white blood cells (lymphocytes) in cancer and infections disease. My laboratory discovered an antigen receptor on lymphocytes (the gamma-delta T cell receptor) and the system for the detection of lipid-containing antigens (mediated by CD1 lipid antigen presenting molecules). These constitute fundamental principles with relevance to the control of cancer and infectious diseases.
Alexander S. Brodsky, PhD (2001)
Research Fellow in Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM 922
Boston, MA 02115
Phone: (617) 632-5105
E-mail: alex_brosky@dfci.harvard.edu
Current Research Interests:
I am developing a new technology to screen RNA-protein interactions on a genomic scale. I am particularly interested in exploring RNA-protein interactions involved in cancers and neural development. RNA-protein interactions play critical roles in regulating gene expression and represent an underdeveloped field in understanding their role in cancer.
Honors/Awards:
Best poster, new innovative project, Cancer Biology retreat, 2002
Myles Brown, MD (1992)
Associate Professor of Medicine
Harvard Medical School
Chief, Division of Molecular and Cellular Oncology
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-3948
Fax: (617) 632-5417
E-mail: myles_brown@dfci.harvard.edu
Website: research.dfci.harvard.edu/brownlab/
Current Research Interests:
Research in my laboratory is focused on the mechanism of action of steroid hormone receptors and their role in cancer. Our major contribution to the field has been the elucidation of the importance of coregulators in determining the action of the estrogen receptor in breast cancer and the androgen receptor in prostate cancer.
Honors/Awards:
President, Boston Area Receptor Society, 1995-1997
Elected member, American Society for Clinical Investigation, 1997
Michael A. Caligiuri, MD (1988)
John L. Marakas Nationwide Professor of Cancer Research, Department
of Medicine
Associate Director for Clinical Research, Comprehensive Cancer Center
Cancer Genetics Scholar, Division of Human Cancer Genetics
Director, Division of Hematology/Oncology
The Ohio State University College of Medicine
320 W. 10th Avenue, A458 SL
Columbus, OH 43210
Phone: (614) 293-7521
Fax: (614) 293-7522
E-mail: caligiuri-1@medctr.osu.edu
Current Research Interests:
My research focuses on natural killer cell immunity and biologic response modifiers in AIDS lymphoma. I have both clinical and laboratory expertise in acute myeloid leukemia, posttransplant lymphoma, or posttransplant lymphoproliferative disorder (PTLD).
Honors/Awards:
Emil J. Freireich Award in Clinical Cancer Research, M.D. Anderson Cancer Center
Elected Fellow, American College of Physicians, 1998
Elected Member, American Society of Clinical Investigation
Distinguished Scholar Award, The Ohio State University
Hsiu-Ching Chang, PhD (2002)
Assistant Professor of Medicine
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street, D1540C
Boston, MA 02115
Phone: (617) 632-4497
E-mail: hsiu-ching_chang@dfci.harvard.edu.
Current Research Interests:
The focus of my laboratory is to study the functional impacts of CD8ab in the antigen recognition of human melanoma. Utilizing recombinant DNA techniques, we are producing soluble recombinant hCD8 ab protein for crystallographic study in complex with HLA-A1-MAGE-3 antigen. A T cell hybridoma system expressing human TCR recognizing MAGE-3 has been generated to test the designed antigens for triggering better immune response.
Joanne Chan, PhD (2002)
Instructor in Medicine
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-4316
Fax: (617) 632-4770
E-mail: jochan@mbcrr.harvard.edu
Current Research Interests:
One way to control cancer growth is to starve the tumor by cutting off its blood supply. I am interested in the molecules that regulate blood vessel formation in normal development and in tumor vessels. To study angiogenesis, I use anti-angiogenic inhibitors and molecular reagents to perturb blood vessel formation in zebrafish embryos and adults.
Sandy Chang, MD, PhD (2001)
University of Texas M.D. Anderson Cancer Center
1515 Holcombe Boulevard Box 11
Houston, TX 77030
Current Research Interests:
Information not available
Lynda Chin, MD (2001)
Assistant Professor of Dermatology
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, M413
Boston, MA 02115
Phone: (617) 632-6091
E-mail: lynda_chin@dfci.harvard.edu
Current Research Interests:
My research interests are molecular genetics of cancer initiation, progression and maintenance, with particular emphasis on development and characterization of mouse models for malignant melanoma and malignant brain tumors. Using these genetically defined models, complemented by examination of human tumor samples, we employ cutting-edge genomic technologies to identify novel genes and pathways involved in the evolution of these deadly cancers.
Honors/Awards:
Charles E. Culpeper Medical Scholarship in Medical Sciences
The Goldhirsh Foundation Brain Tumor Research Award
Antonio J. da Silva, PhD (1994)
Scientist
Biogen, Inc.
12 Cambridge Center
Cambridge, MA 02142
Phone: (617) 679-3375
Fax: (617) 679-3208
Current Research Interests:
My primary activity concerns the development and launching of a novel biologic (recombinantly engineered fusion protein) for the treatments of autoimmune diseases. I have been involved in research, related to the development of the new drug, Amevive, initially being marketed for the treatment of moderate to severe psoriasis. I am also working in functional genomics, aiming at identifying novel targets for therapeutic development for the treatment of immune disorders.
Patricia L. M. Dahia, MD, PhD (2002)
Instructor in Medicine
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM1010
Boston, MA 02115
Current Research Interests:
I have been interested in understanding the mechanisms of normal and tumoral development of the neural crest, in particular tumors arising from chromaffin cells and related sympathetic and parasympathetic ganglia. My recent work has focused on the study of hereditary tumor forms as a model to unfold the basis of these neural crest disorders.
James DeCaprio, MD (2001)
Associate Professor of Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, M457
Boston, MA 02115
Phone: (617) 632-3825
Fax: (617) 632-4760
E-mail: james_decaprio@dfci.harvard.edu
Current Research Interests:
My laboratory studies the process of oncogenesis focusing on the mechanisms of transformation by SV40 large T antigen. Specific interests include the study of tumor suppressers and the cell cycle.
Honors/Awards:
Stohlman Scholar, Leukemia and Lymphoma Society
Glenn Dranoff, MD (1994)
Associate Professor of Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, D510E
Boston, MA 02115
Phone: (617) 632-5051
E-mail: glenn_dranoff@dfci.harvard.edu
Current Research Interests:
My laboratory studies the cellular and molecular mechanisms underlying the generation of anti-tumor immunity. We have an active program to translate our discoveries to a clinical program of vaccination with genetically modified tumor cells for patients with melanoma, lung cancer, ovarian cancer, and leukemia.
Honors/Awards:
Eli Lilly Biochemistry Award in Gene Therapy
Academy of Cancer Immunology
Associate Director, Scientific Advisory Council, Cancer Research Institute
Jonathan Duke-Cohan, PhD (2001)
Instructor in Medicine
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street, D1526
Boston, MA 02115
Phone: (617) 632-3122
Fax: (617) 632-3160
E-mail: jonathan_duke-cohan@dfci.harvard.edu
Website: research.dfci.harvard.edu/attractin
Current Research Interests:
My research focuses on molecular events underlying changes in immune cell shape and motility during an immune response. A remarkable aspect of these studies is the demonstration that the same mechanisms underlie control of skin and hair pigmentation and control of brain and spinal cord structure. Thus, results from any one of these arenas gives a tremendous boost to our knowledge of mechanism that may prove to be essential for proper understanding and handling of both immune responses and neurodegeneration.
Michael J. Eck, MD, PhD (1997)
Assistant Professor of Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM1036
Boston, MA 02115
Phone: (617) 632-5860
E-mail: eck@red.dfci.harvard.edu
Current Research Interests:
My laboratory studies the three-dimensional structure of proteins and protein complexes that are important for regulation of cell growth and division. We are particularly interested in Src-family tyrosine kinases and interacting proteins, and in other proteins that might be targets for development of anticancer drugs.
Honors/Awards:
BASF/DFCI Young Investigator Award, 1999
Charis Eng, MD, PhD, FACP (1997)
William C. & amp; Joan E. Davis Professor of Cancer Research
Professor of Medicine, Human Cancer Genetics & Molecular Genetics
Director, Clinical Cancer Genetics Program
Co-Director, Division of Human Genetics
Human Cancer Genetics Program
Dept. of Internal Medicine
The Ohio State University
420 W. 12th Avenue, Ste 690 TMRF
Columbus, OH 43210
Phone: (614) 292-2347
Fax: (614) 688-3582
E-mail: eng.25@osu.edu
E-mail: eng-1@medctr.osu.edu
Current Research Interests:
The broad thrust of my clinical cancer genetics translational research laboratory involves the utilization of multiple strategies to identify, characterize and understand genes which cause susceptibility to inherited cancer syndromes, to determine their role in sporadic carcinogenesis and to perform molecular epidemiologic analyses as they might relate to clinical care.
Honors/Awards:
International Scientific Committee, International Workshops on Multiple Endocrine Neoplasia, 1999
Fellow of American College of Physicians, 1999
Elected member, American Society for Clinical Investigation, 2001
Chair, 2003 Scientific Program Committee, Annual Meeting, American Society of Human Genetics, 2001
William C. and Joan E. Davis Endowed Professorship, 2001
Harry de Lozier Memorial Lecturership, 2002
Stephanie Spielman Breast Cancer Research Award, James Cancer Hospital and Solove Research Institute, The Ohio State University, Columbus, OH, 2002
Honorary Fellow, Cancer Research UK Human Cancer Genetics Research Group, The University of Cambridge, England
James L.M. Ferrara, MD (1990)
Professor and Director
Combined Bone Marrow Transplantation Program
University of Michigan Cancer Center, CGC 6308
1500 E. Medical Center Drive
Ann Arbor, MI 48109-0942
Phone: (734) 615-1340
Fax: (734) 647-9271
E-mail: ferrara@umich.edu
Current Research Interests:
Since coming to the University of Michigan to direct the Bone Marrow Transplantation Program in 1998, I remain engaged in research into the mechanisms of graft versus host disease, the major complication of allogeneic bone marrow transplantation. Our results of the last several years have led to innovative trials of new drugs in our BMT patients, which are currently ongoing.
Honors/Awards:
Junior Faculty Research Award, American Cancer Society, 1990
Scholar Award, Leukemia Society of America, 1993
Elected Member, American Society for Clinical Investigation, 1997
Stohlman Scholar, Leukemia Society of America, 1996
Alexander von Humboldt Research Prize, German Republic, 1997
"America's Top Doctors" Citation, 2001
David E. Fisher, MD, PhD (1993)
Associate Professor of Pediatrics
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, D630
Boston, MA 02115
Phone: (617) 632-4916
Fax: (617) 632-2085
E-mail: david_fisher@dfci.harvard.edu
Current Research Interests:
Our laboratory studies transcriptional regulation in melanocyte and osteoclast development. These areas are of importance in several medical conditions including osteoporosis, melanoma, and deafness.
Honors/Awards:
American Society of Hematology Scholar Award
Pew Foundation Scholars Award
McDonnell Foundation Research Scholar
Charlotte Geyer Foundation Research Award
American Society for Clinical Investigation
Gertrude B. Elion Award for Cancer Research, American Association for Cancer Research
Fannie E. Rippel Foundation Research Award
Faculty Award for Teaching, Biological and Biomedical Sciences
Graduate Program, Harvard Medical School
Scientific Advisory Board, William Guy Forbeck Cancer Research Foundation
Member NIH Study Section: Cell Development and Function-5
Sidney Kimmel Symposium for Cancer Research Scholar Award, American Association for Cancer Research
Christina Frederick, PhD (2001)
Information not available.
Current Research Interests:
Information not available.
Gordon Freeman, PhD (2002)
Assistant Professor of Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-4585
Fax: (617) 632-5167
E-mail: gordon_freeman@dfci.harvard.edu
Current Research Interests:
My work has focused on the molecular cloning and functional characterization of the B7 gene family of costimulatory molecules of the immune system. Recently, my laboratory has begun to study the role of cell death in the immune response and in tumor development. Porimin, a cell surface protein whose crosslinking causes cells to rapidly die mediates a novel form of cell death, distinct from the well-studied form of cell death termed apoptosis. To better understand the mechanism of porimin-mediated cell death, we are identifying the proteins that interact with porimin and transmit the death signal into the cell; to better understand the essential function of the porimin death pathway in vivo, we are studying cell death and tumor development in our porimin knockout mouse model.
Dana Gabuzda, MD (1992)
Associate Professor of Neurology
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street, JF816
Boston, MA 02115
Phone: (617) 632-2154
E-Mail: dana_gabuzda@dfci.harvard.edu
Current Research Interests:
My laboratory is involved in basic research on AIDS. Studies are focused on understanding molecular mechanisms that lead to immunodeficiency and neurologic disease in HIV infection.
Honors/Awards:
Elizabeth Glaser Scientist Award, Pediatric AIDS Foundation, 1998
Todd R. Golub, MD (1996)
Associate Professor of Pediatrics
Harvard Medical School
Associate Investigator
Howard Hughes Medical Institute
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, D640C
Boston, MA 02115
Phone: (617) 632-4903
Fax: (617) 632-4850
E-mail: todd_golub@dfci.harvard.edu
Current Research Interests:
My current research focuses on bringing the Human Genome Project to the study of cancer biology and cancer medicine. Specifically, my laboratory is taking genomic approaches to identifying new critical targets in cancer, and predicting the response of patients to all cancer drugs.
Honors/Awards:
Cheryl Whitlock Memorial Prize in Hematopoiesis and Leukemia, 1997
Junior Faculty Scholar Award, American Society of Hematology, 1998
Discover Magazine Inventor of the Year (Health Category), 2000
Judson Daland Prize for Outstanding Achievement in Clinical Investigation, American Philosophical Society, 2001
Cornelius Rhoads Memorial Prize, American Association for Cancer Research, 2002
Fotini Gounari, PhD (2002)
Instructor of Pathology
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-6884
Fax: (617) 632-6881
Current Research Interests
:I am currently studying the role of pre-TCR in the development of leukemia. Recent studies indicated that Notch- and E2A-induced leukemias are pre-TCR dependent. I am analyzing the way in which pre-TCR is involved in Notch-induced leukemia.
Jeremy B.A. Green, PhD (1995)
Assistant Professor of Genetics
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-4580
Fax: ( 617) 632-4584
E-mail: jeremy_green@dfci.harvard.edu
Current Research Interests:
My laboratory is studying the signals that guide cellular growth and differentiation in developing amphibian embryos. Cancer can, in part, be considered to be a defect in these signals and the molecules involved are often identical to those implicated in human carcinogenesis. We have focused on the beta-catenin protein, whose overabundance causes the majority of human colon cancers and which is responsible for head development in amphibians. We have identified novel regulatory mechanisms involving the GSK-binding protein GBP and a group of cell polarity proteins encoded by the Par genes.
Steven R. Grossman, MD, PhD (2000)
Assistant Professor of Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-5098
Fax: (617) 632-4381
E-mail: sgrossman@partners.org
Current Research Interests:
I am investigating the mechanism by which the tumor suppressor p53 is regulated in normal and cancer cells. My work focuses on the destruction of p53, which keeps it in check in normal cells, but its destruction is often overactive in cancer cells, allowing abnormal growth of these cells. Therapeutic agents that block the destruction of p53, and increase its levels, in cancer cells but not normal cells, might stop the growth of tumors without the side-effects of current cancer treatments.
Honors/Awards:
Kimmel Scholar Award, 2002
James D. Griffin, MD (1999)
Professor of Medicine
Harvard Medical School
Chair, Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, D1608
Boston, MA 02115
Phone: (617) 632-3360
E-mail: james_griffin@dfci.harvard.edu
Current Research Interests:
My major research interests include regulation of hematopoiesis, biology of myeloid leukemias, leukemia oncogenes as targets for drug development and notch receptor function.
Honors/Awards:
National Board of Trustees, Leukemia and Lymphoma Society, 2000
Dr. Anthony D. Cortese Award, Leukemia and Lymphoma Society of America, 2001
Elected to Association of American Physicians, 2001
National Trustee, Leukemia and Lymphoma Society, 2001
Prasad V.S. Kanteti, PhD (1995)
Associate Professor
Department of Microbiology and Immunology
Medical Sciences Building
835 South Wolcott Ave., Rm# E820
University of Illinois at Chicago
Chicago, IL 60612
Phone: (312) 413-3423
Fax: (312) 996-8527
E-mail: kanteti@tigger.uic.edu
Current Research Interests:
My laboratory has identified a twenty amino acid amphipathic helical region in Siva-1, a pro-apoptotic molecule that is enough to sensitize breast cancer cells to cancer therapy. Currently, we are exploring this region in Siva-1 for use as an adjuvant in cancer therapy. My lab is also investigating the biological role of Siva-1 using transgenic and knockout mouse models.
Khashayarsha Khazaie, PhD, DSc (2000)
Instructor in Pathology
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-6883
Fax: (617) 632-6881
E-mail: khashayarsha_khazaie@dfci.harvard.edu
Current Research Interests:
My laboratory is studying an animal model for immunotherapy of colon cancer and evaluation of potential risk of causing inflammatory bowel disease. We are also developing an animal model of inducible mammary cancer to study antigen specific immune responses against the mammary gland and mammary tumors.
Andrew L. Kung, MD, PhD (2001)
Assistant Professor of Pediatrics
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, SM814
Boston, MA 02115
Phone: (617) 632-5731
Fax: (617) 632-4381
E-mail: andrew_kung@dfci.harvard.edu
Current Research Interests:
My research is focused on the identification of new targets for the development of cancer therapies. We are also developing improved methods for modeling tumors in small animals, both for the study of cancer biology, as well as the testing of new therapies.
Honors/Awards:
Howard Temin Award, National Cancer Institute, NIH
Goldhirsh Foundation Research Award
Adam Lerner, MD (1991)
Section of Hematology/Oncology
Boston Medical Center
Evans Biomedical Research Center, Room 427
650 Albany Street
Boston, MA 02118
Phone: (617) 638-7504
Fax: (617) 638-7530
E-mail: alerner@medicine.bu.edu
Current Research Interests:
My laboratory is studying novel therapies for breast cancer and leukemia. Specifically, we are studying three new forms of therapy for chronic lymphocytic leukemia, as well as a gene that we believe may account for the ability of breast cancers to become resistant to hormonal therapy.
Anthony Letai, MD, PhD (2001)
Instructor in Medicine
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-2348
E-mail: anthony_letai@dfci.harvard.edu
Current Research Interests:
My research focuses on the role of members of the BCL-2 family of proteins in causing and maintaining cancer using transgenic mice and in vitro studies. Inhibiting a protein of this family promotes survival of cancer cells.
Honors/Awards:
American Society of Hematology Scholar Award
Leukemia and Lymphoma Society Scholar
Frederick P. Li, MD (1991)
Professor of Medicine
Harvard Medical School
Professor of Clinical Cancer Epidemiology
Harvard School of Public Health
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, SM201
Boston, MA 02115
Phone: (617) 632-2508
Fax: (617) 632-3161
E-mail: fli@partners.org
Current Research Interests:
My current research focuses on inherited susceptibility to common forms of cancer, particularly cancers of the breast and colon and childhood cancers. Recently, my work has been extended to include interventions research on those with high cancer risk due to inborn susceptibility and/or environmental exposures such as cigarette smoking. Another emerging interest is chemoprevention, the use of medications that might prevent or delay cancer development among those at high risk
.Honors/Awards:
Fourth American Cancer Society Award for Research Excellence in Cancer Epidemiology and Prevention, 1995
Charles S. Mott Prize, General Motors Cancer Research Foundation, 1995
ASCO-ACS Award for Cancer Prevention Research, 1998
Harry and Elsa Jiler American Cancer Society Clinical Research Professorship, 1998
ACS Medal of Honor for Clinical Research
Massimo F. Loda, MD (1998)
Associate Professor of Pathology
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, D740
Boston, MA 02115
Phone: (617) 632-4001
Fax: (617) 632-4005
E-mail: massimo_loda@dfci.harvard.edu
Current Research Interests:
My laboratory is studying the family of de-ubiquitinating enzymes, which can reverse the process that targets cellular molecules for destruction. We recently discovered that one such enzyme, USP2, is abundant in prostate tumors and is essential for tumor cell survival. Inhibition of this enzyme results in significant prostate cancer cell death. We have also been studying cell cycle regulation in human solid tumors and have established the prognostic role of the cell cycle inhibitor p27. To study p27's role in this tumor at the molecular level, we have established an animal model of Barrett's Associated Adenocarcinoma and utilized it in p27 knock-out strains in which we are testing pre-clinically inhibitors of kinases which p27 itself inhibits physiologically. We are also developing an animal model for the identification of prostate stem cells, to study prostate development and neoplastic transformation in vivo.
A. Thomas Look, MD (2001)
Professor of Pediatrics
Harvard Medical School
Vice-Chair for Research
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, M630
Boston, MA 02115
Phone: (617) 632-5826
Fax: (617) 632-6989
E-mail: thomas_look@dfci.harvard.edu
Current Research Interests:
Our laboratory is interested in the genetic models of leukemogenesis and rhabdomyosarcoma, with the goal of understanding the pathways of cell death specification in mammals how they connect to the common machinery of apoptosis, or programmed cell death, and how they can be disrupted in malignant transformation. A new research area for us is the use of the zebrafish genetic system to clarify developmental pathways subverted in human leukemias and solid tumors. The zebrafish animal model provides a powerful system for genetic analysis of vertebrate embryogenesis, organ development and disease.
Honors/Awards:
Visiting Professor, Puerto Rico Society of Hematology & Medical Oncology, Fajardo, PR, 2001
10th Annual Pediatric Cancer Research Foundation Memorial Lectureship, Newport Beach, CA, 2002
Kathryn Lunetta, PhD (1999)
Director of Biostatistics
Genomics Collaborative, Inc.
99 Erie Street
Cambridge, MA 02139
Phone: (617) 999-2223
Fax: (617) 661-8899
E-mail: klunetta@genomicsinc.com
Current Research Interests:
My current research involves the identification of gene polymorphisms that effect the risk of complex diseases including cancer, cardiovascular disease, and rheumatoid arthritis.
Qiufu Ma, PhD (1999)
Assistant Professor of Neurobiology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM1022
Boston, MA 02115
Phone: (617) 632-4594
E-mail: qiufu_ma@dfci.harvard.edu
Current Research Interests:
My laboratory studies the development of the sensory neurons crucial for senses of pain, blood pressure, and blood oxygen level. We have identified two families of molecules that are essential for formation of pain-related sensory neurons. In addition, my lab has identified and continues to work on several molecules critical for specification of the serotonin neurons. Defects of serotonin neurons have been implicated in many behavioral problems, such as anxiety, depression, and/or aggression.
Honors/Awards:
Pew Scholar in Biomedical Science, 2000
SCBA Young Investigator Award, 2001
Bernard Mathey-Prevot, PhD (1999)
Associate Professor of Pediatrics
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, M649B
Boston, MA 02115
Phone: (617) 632-3535
Fax: (617) 632-5757
E-mail: bernard_mathey-prevot@dfci.harvard.edu
Current Research Interests:
My laboratory is studying how blood progenitor cells can sense and interpret outside cues and translate them into orchestrated nuclear signals resulting in cell survival, proliferation or commitment to differentiation. We are studying this problem in the fruit fly, Drosophila melanogaster, because it offers unparallel tools to exploit genetics. Insights into Drosophila blood development will have broad implications for understanding mammalian hematopoiesis and leukemogenesis. We have isolated a key player triggering an innate immunity response against gram negative bacteria and we have identified a novel gene involved in blood differentiation in flies that is evolutionary conserved.
Matthew L. Meyerson, MD, PhD (1998)
Assistant Professor of Pathology
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, M446
Boston, MA 02115
Phone: (617) 632-4768
E-mail: matthew_meyerson@dfci.harvard.edu
Current Research Interests:
My laboratory is focused on three areas of research. We are conducting genomic studies of human lung cancers to improve lung cancer classification and to understand lung cancer pathogenesis by a combination of gene expression profiling, chromosomal analysis, and mutation discovery. We are pursuing functional studies of the MEN-1 tumor suppressor gene to understand the role that this gene plays in regulating cell growth and differentiation, by applying gene inactivation methods and studying multiprotein complexes. Also, we have developed a new method, "computational subtraction," to identify viruses that cause cancer and other human diseases, and we are now applying this method to discover infectious agents in lymphomas.
Honors/Awards:
Pew Scholar in the Biomedical Sciences
Michael T. Michalek, PhD (1993)
Principal Scientist
Genomic Profiling Systems
840 Memorial Drive, 4th Floor
Cambridge, MA 02139
Phone: (617) 547-7070 x34
E-mail: mike@genprosys.com
E-mail: mmichalek@sprintmail.com
Current Research Interests:
My current scientific activities are focused on the development of technologies for detecting and identifying microscopic and sub-microscopic targets (e.g., bacteria, viruses, proteins, and DNA). These technologies are based on large-area digital imaging using the company's proprietary Direct Imaging platform.
Elisabetta Mueller, PhD (2001)
Instructor in Cell Biology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-4660
E-mail: elisabetta_mueller@dfci.harvard.edu
Current Research Interests:
My research interest is on the transcriptional and genetic mechanisms regulating cellular differentiation and carcinogenesis. My work has focused on the nuclear receptor PPAR-gamma, a master regulator of adipocyte differentiation, extending the understanding of PPAR-gamma function beyond adipose biology and lipid metabolism to demonstrate the role of this nuclear receptor as a tumor suppressor in multiple tissues, including breast, colon and prostate. I am currently analyzing the molecular effectors of PPAR-gamma's specific function in different tissues by utilizing cell lines with genetic ablation of this transcription factor and animal models of carcinogenesis.
Yoshihir Nakatani, PhD (2000)
Professor of Biological Chemistry and Molecular Pharmacology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-4766
E-mail: yoshihir_nakatani@dfci.harvard.edu
Current Research Interests:
Every human cell contains between 30,000 to 60,000 individual genes. However, only about 1/3 of the genetic repertoire is expressed in any given cell type. My laboratory is interested in the proteins that regulate gene expression. Mutations in these proteins lend to inappropriate gene expression and cancer.
David Pellman, MD (1994)
Associate Professor of Pediatrics
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, M621A
Boston, MA 02115
Phone: (617) 632-4918
E-mail: david_pellman@dfci.harvard.edu
Current Research Interests:
My laboratory is focused on understanding how cell cycle signals control cell shape and chromosome segregation. The projects on chromosome segregation have lead us to study how cells adapt to increases in chromosome number, a common feature of cancer cells. This has led to efforts to identify drugs that specifically kill cells with altered chromosome number.
Honors/Awards:
Damon Runyon Scholar Award, 1995-1997
Member, Blood Journal Editorial Board, 1997-present
Kimmel Scholar Award, 1998
Graduate Student Mentoring Award, Harvard Medical School, 1999
BASF Bioresearch Award, Dana Farber Cancer Institute, 2000
Scholar Award, Leukemia and Lymphoma Society, 2000
Elected Member, American Society for Clinical Investigation, 2001
Kornelia Polyak, MD, PhD (1998)
Assistant Professor of Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, D740C
Boston, MA 02115
Phone: (617) 632-2106
Fax: (617) 632-4005
E-mail: kornelia_polyak@dfci.harvard.edu
Current Research Interests:
The focus of my laboratory is to investigate the molecular basis of breast cancer initiation and progression. We are using genomics technologies including SAGE (Serial Analysis of Gene Expression) to identify novel genes and pathways involved in breast tumorigenesis. Following the identification of these genes, we are designing studies to understand the biological function of these genes, such as the HIN-1 (High in Normal-1) novel growth inhibitory cytokine. Our eventual goal is to use this information to improve the clinical management of breast cancer patients.
Honors/Awards:
Scholar Award, Sidney Kimmel Cancer Foundation, 1999
V Scholar Award, V Foundation, 2001
Sidney Kimmel Symposium for Cancer Research Scholar, American Association for Cancer Research, 2002
Vivienne Rebel, MD, PhD (2001)
Instructor in Pediatrics
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM 816
Boston, MA 02115
Phone: (617) 632-4593
E-mail: vivienne_rebel@dfci.harvard.edu
Current Research Interests
:My research interests lies in gaining insight into the regulatory mechanisms of stem cell biology, particularly of blood-forming stem cells. Specifically, my research is framed around questions regarding tissue-engineering and cancer biology.
Honors/Awards:
Leukemia & Lymphoma Society Special Fellow Award
Hans Reiser, MD (1990)
Director of Biology
Boehringer Ingelheim Pharmaceuticals, Inc.
900 Ridgebury Road/P.O. Box 368
Ridgefield, CT 06877-0368
Phone: (203) 798-5401
Fax: (203) 791-6196
E-mail: hreiser@boehringer-ingelheim.com
Current Research Interests:
My current research responsibilities include the discovery laboratories, protein chemistry, physical biochemistry, genomics, proteomics and bioinformatics, with a research focus on autoimmune diseases, inflammation, and allergy asthma.
Ilonna J. Rimm, MD, PhD (1993)
Director of Technology Licensing
Global Business Development
Wyeth Pharmaceuticals
87 Cambridge Park Drive
Cambridge, MA 02140
Phone: (617) 665-7256
Fax: (617) 868-1024
E-mail: irimm@wyeth.com
Current Research Interests:
My current work involves providing technology licensing support for the Genomics group. In this position, I assist the scientists with the choice of the most appropriate new technology for their scientific needs.
Charles Roberts, MD, PhD (2001)
Instructor in Pediatric Oncology
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, M655
Boston, MA 02115
Phone: (617) 632-6497
E-mail: charles_roberts@dfci.harvard.edu
Current Research Interests:
My laboratory is studying the involvement of chromatin remodeling in tumor suppression. As a model system, we are investigating the function of Snf5, a core member of the Swi/Snf chromatin remodeling complex that is specifically inactivated in the aggressive pediatric cancer malignant rhabdoid tumor. We have generated conditionally targeted alleles of SNF5 in mice and are characterizing its normal function and its role in tumor suppression.
Michael John Robertson, MD (1990)
Director, Lymphoma Program
Associate Professor of Medicine
Stem Cell Transplantation Program and
Division of Hematology/Oncology
Indiana University Medical Center
1044 W. Walnut Street, R4-202
Indianapolis, IN 46202
Phone: (317) 274-0843
Fax: (317) 278-2262
E-mail: mjrobert@iupui.edu
Current Research Interests:
I am currently engaged in both clinical and translational research devoted to developing novel immunologic approaches to cancer treatment.
Barrett J. Rollins, MD, PhD (2001)
Associate Professor of Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-3896
E-mail: barrett_rollins@dfci.harvard.edu
Current Research Interests:
My laboratory is focused on research in the areas of chemokine biology, histiocytic diseases, and cell cycle abnormalities in lung cancer.
David H. Rowitch, MD, PhD (1998)
Assistant Professor of Pediatrics
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, D640D
Boston, MA 02115
Phone: (617) 632-4201
Fax: (617) 632-4850
E-mail: david_rowitch@dfci.harvard.edu
Current Research Interests:
My laboratory is interested in understanding the role of Hedgehog signaling during specification of specialized cell types in the central nervous system (CNS) during development and also how this pathway regulates proliferation both in CNS precursors cells and brain tumors.
Christopher E. Rudd, PhD, DSc, FRCPath, FMedSci (1990)
Professor of Haematology
Chair of Haematology
Department of Haematology
Director of Research
Division of Investigative Science
Faculty of Medicine
Imperial College, London
Hammersmith Hospital Campus
Du Cane Road, London
W12 ONN
Phone: (44) 208-383-8421
Fax: (44) 208-383-8434
E-mail: c.rudd@ic.ac.uk
Current Research Interests:
My laboratory is studying the receptors and intracellular proteins that control T-cell activation and effector responses. Several adapter proteins, proteins that lack enzymatic activity or transcription activation domains, and instead possess binding sites or discrete modules that bind to other proteins, have been identified in my laboratory. These include ADAP (adhesion and degranulation promoting adaptor protein) and SKAP-55. We have shown that these proteins play key roles in controlling the ability of T-cells to interact with antigen presenting cells and tumour cells, a central event in the elimination of tumours. We also have a major interest in understanding the nature of signals generated by co-receptors CD28, ICOS and CTLA-4 in the modification of T-cell immunity.
Honors/Awards:
Wellcome Principal Research Fellowship
Fellow in the Royal
College of Pathologists (FRCPath)
Academy of Medical Sciences
(FMedSci), London
Dietmar Schmucker, PhD (2001)
Assistant Professor of Neurobiology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM1022C
Boston, MA 02115-6084
Phone: (617) 632-2453
Fax: (617) 632-6499
E-mail: dietmar_schmucker@dfci.harvard.edu
Current Research Interests:
My research is focusing on investigating molecular mechanisms that control the development of sensory nerves, using the powerful genetics of the model organism Drosophila (fruit fly) to characterize genes that allow growing nerve processes to connect to other nerve cells and form a functional brain. We have identified a protein (Dscam) that is important for brain development and highly related to the human protein Down Syndrome Cell Adhesion Protein (DSCAM). We are addressing the question of whether the exceptional molecular diversity of Dscam contributes directly to the connection specificity of complex neuronal circuits. We propose that different Dscam isoforms constitute a molecular recognition code that provides individual neurons with instructions to connect with the correct target neurons in the developing brain.
Honors/Awards:
Chestnut Hill Charitable Foundation's New Investigator Award,
2001
Pew Scholar in the Biomedical Sciences, 2002
Rosalind Segal, MD, PhD (1998)
Associate Professor of Neurobiology
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, D620
Boston, MA 02115
Phone: (617) 632-4737
E-mail: rosalind_segal@dfci.harvard.edu
Current Research Interests:
The research in my laboratory focuses on growth factors that regulate the normal development of the brain, and how the normal processes of growth, differentiation and survival are usurped in diseases. Our studies focus on modulators that alter the nature of the biological response to growth factors. We have found that the timing and location of growth factor release and function contribute to specificity of responses to a single growth factor, and we have identified additional modulators of growth factor signaling. We are investigating the ways in which aberrant localization of growth factor signaling molecules contribute to cancers.
William R. Sellers, MD (1997)
Assistant Professor of Medicine
Harvard Medical School
Department of Medical Oncology
Dana-Farber Cancer Institute
44 Binney Street, D720C
Boston, MA 02115
Phone: (617) 632-5261
Fax: (617) 632-5417
E-mail: william_sellers@dfci.harvard.edu
Website: research.dfci.harvard.edu/sellerslab/index.html
Current Research Interests:
The central focus of my laboratory is to study the molecular underpinnings of prostate cancer. We are focusing our research in two major areas: 1) candidate gene approaches that are currently focused on understanding the role of the PTEN tumor suppressor gene product in regulating cell homeostasis, and 2) whole genome approaches to the classification of prostate cancer.
Jyoti Sen, PhD (2000)
Assistant Professor Pediatrics
Harvard Medical School
Department of Pediatrics
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-3869
Fax: (617) 632-4367
E-mail: jyoti_sen@dfci.harvard.edu
Current Research Interests:
In our studies of the role of beta-catenin signaling pathway in T cells, we have discovered that beta-catenin is a target of signals essential for the generation of mature T cells. Our studies point to mechanisms by which interfering with beta-catenin signals may modulate the immune system. We have also shown that beta-catenin signals play an important role in the age-related involution of the thymus.
Ramesh A. Shivdasani, MD, PhD (1996)
Assistant Professor of Medicine
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street
Boston, MA 02115
Phone: (617) 632-5746
E-mail: ramesh_shivdasani@dfci.harvard.edu
Current Research Interests:
My laboratory is studying molecular mechanisms of two distinct processes: development of the vertebrate gastrointestinal tract and fragmentation of differentiated megakaryocytes to release blood platelets. We are focusing our research on the basis of communication between the prospective intestinal epithelium and its underlying mesenchyme and of the extensive cytoskeletal morphogenesis that accompanies platelet release.
Honors/Awards:
Physician Scholar of the Cancer Research Fund (Damon Runyon-Walter Winchell Foundation)
Scholar of the Leukemia and Lymphoma Society
Peter Sicinski, MD, PhD (1998)
Assistant Professor of Pathology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM936
Boston, MA 02115
Phone: (617) 632-5005
E-mail: peter_sicinski@dfci.harvard.edu
Current Research Interests:
Our laboratory studies the role of cell cycle machinery in development and in cancer. We are generating various knockout and "knock-in" mouse strains and we are analyzing their development and their predisposition to different cancers. We also are deriving cells from mutant animals and using them for analysis at the cellular and molecular levels.
Honors/Awards:
AACR - Gertrude B. Elion Cancer Research Award, 2002
Abbott Bioresearch Center Award, 2002
Colin A. Sieff, MD (1999)
Associate Professor of Pediatrics
Harvard Medical School
Department of Pediatric Oncology
Dana-Farber Cancer Institute
44 Binney Street, M612
Boston, MA 02115
Phone: (617) 632-3531
E-mail: colin_sieff@dfci.harvard.edu
Current Research Interests:
My research interests concern congenital and inherited bone marrow failure syndromes in children, many of which are associated with an increased risk of developing cancer. My particular focus is on a congenital failure of red cell production called Diamond Blackfan Anemia (DBA) that is inherited in some cases and is associated both with other developmental abnormalities and with an increased risk of leukemia. One gene, a ribosomal protein gene called RPS19, is mutated in about 20% of cases. We have mapped a second gene to the 8p chromosome, and we know that at least one additional gene is involved. Our work focuses on identifying the other DBA genes, determining how RPS19 mutations cause anemia, and developing gene therapy for patients with RPS19 mutations.
Pamela Silver, Phd (1993)
Professor of Biological Chemistry & Molecular Pharmacology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM922
Boston, MA 02115
Phone: (617) 632-5102
E-mail: pamela_silver@dfci.harvard.edu
Current Research Interests:
My group studies several major areas in cell biology including: trafficking of macromolecules, the dynamic organization of the nucleus, and post-transcriptional regulation in neural development and cancer. Results from these studies have far-reaching implications for the mechanisms of action of, for example, tumor suppressors in cancer and infectivity of HIV. Our experiments use a wide range of approaches and employ both model organisms such as yeast and mammalian cells. We are also investigating new approaches that can be applied to unsolved problems in cell biology and allied fields including genome-scale transcriptome/protein interactions and characterization of immense protein complexes in living cells
.Honors/Awards:
Council Member of the American Society for Cell Biology, 1996-1999
Board of Scientific Advisors, Jane Coffin Childs Memorial Fund, 2000-2004
Editor, Molecular Biology of the Cell, 2001
BBS Mentoring Award, Harvard Medical School, 2002
Neil Lee Spector, MD (1989)
Adjunct Associate Professor of Medicine
Division of Hematology/Medical Oncology
Lineberger Comprehensive Cancer Center
University of North Carolina-Chapel Hill
Chapel Hill, NC
Five Moore Drive
PO Box 13398
Experimental Medicine
Research Triangle Park, NC 27709-3398
Phone: (919) 483-1525
Fax: (919) 315-0440
E-mail: ns85812@glaxowellcome.com
Current Research Interests:
My research has focused on the role of stress or heat shock proteins in the regulation of cell growth and differentiation of normal and neoplastic cells, the role of this response in providing cytoprotection, and the role of heat shock transcription factor (HSF1) in apoptic pathways. We are also working on the identification of a novel class of benzazapines with selective cell cycle and apoptic effects on epithelial and hematological malignancies, and on the identification of diagnostic/surrogate/biomarkers to facilitate the development of targeted antitumor therapies (e.g., tyrosine kinase inhibitors, angiogenesis inhibitors, cell cycle modulators etc.)
Honors/Awards:
Stanley Glaser Research Foundation Award for Excellence in Cancer Research, American Society of Hematologists, 1994
Bruce M. Spiegelman, PhD (1990)
Professor of Cell Biology
Harvard Medical School
Department of Cancer Biology
Dana-Farber Cancer Institute
44 Binney Street, SM958
Boston, MA 02115
Phone: (617) 632-3567
E-mail: bruce_spiegelman@dfci.harvard.edu
Current Research Interests:
My lab is focused on the control of cell differentiation, especially at the level of gene transcription. We are attempting to develop new approaches to human cancer through promotion of cell differentiation.
Honors/Awards:
Merck-Frost Distinguished Lecturer - Univ. of Alberta, 1996
Merck-Frost Distinguished Lecturer - McGill University, 1997
Heinrich Wieland Prize for Lipid Research, Faculty of Chemistry, University of Munich, Germany, 1997
Yamanouchi USA Foundation Research Award, 1999
Wu Lectureship, Columbia University, 1999
Dewitt Goodman Memorial Lecture, Columbia University, 1999
Mosenthal Lecture, Eastern American Diabetes Association, 1999
Solomon Berson Award, American Physiological Society, 1999
Elected, National Academy of Sciences, USA, 2002
Elected, American Academy of Arts and Sciences, 2002
Christopher S. Stipp, PhD (2001)
Instructor of Pathology
Harvard Medical School
Department of Cancer Immunology and AIDS
Dana-Farber Cancer Institute
44 Binney Street, D1432
Boston, MA 02115
Phone: (617) 632-2617
E-mail: christopher_stipp@dfci.harvard.edu
Current Research Interests:
I am studying a novel protein complexes on the surface of tumor cells that are altered in tumorigenic versus non-tumorigenic cells. These complexes contain (1) members of a new family of proteins, the EWI proteins (2) members of the tetraspanin family of proteins, and (3) alpha-3 integrin, a protein used by tumor cells to migrate. We found that the tetraspanins physically link EWI proteins to alpha-3 integrin and thereby change the ability of alpha-3 to promote tumor cell migration.
Honors/Awards:
Invited Speaker, 2nd International FASEB Meeting on Tetraspanin Research, 2002
Michael Streuli, PhD (1996)
Immunogen Inc.
128 Sidney Street
Cambridge, MA 02139
Current Research Interests:
Information not available.
Pal Subrata, PhD (1989)
Information not available.
Current Research Interests:
Information not available.
Kut-nie Tan, PhD (1988)
President and Scientific Director
Northeast Biomedical Research Institute
100 Cummings Ctr. Suite s-439C
Beverly, MA 01915
Phone: (978) 921-8886
Current Research Interests:
Information not available.
Thomas Wileman, PhD (1988)
Head, Immunology and Pathology
Institite for Animal Health
Pirbright Laboratory
Ash Road, Woking
Surrey, UK
Phone: (0)1482 232441
E-mail: thomas.wileman@bbsrc.ac.uk
Current Research Interests:
We are studying economically important animal viruses as model systems to investigate how viruses subvert cellular signal transduction and membrane traffic pathways to facilitate replication and survival in the host. An understanding of these host-virus interactions at a molecular level gives fresh insight into the function of viral proteins and provides novel targets for the design of anti-viral therapies and vaccines.
Honors/Awards:
International Scholar Award, National Institute for Animal Health,
Japan, 1998 and 2000
Basil O'Connor Scholar Award, March of Dimes, 1989-1992
