Dana-Farber investigators led a phase 1 trial in which a new oral targeted drug, idelalisib, (GS-1101), showed the potential to stave off the need for additional treatments for relapsed or treatment-resistant CLL.
Tags: BasicResearch, Leukemia
Dr. Frei led Dana-Farber from 1973-1980. During the 1950s and 1960s, Dr. Frei became known as the "father of combination chemotherapy" for demonstrating that treatment with multiple chemotherapy agents could produce lasting remissions in children with acute lymphoblastic leukemia.
A type of low-grade but sometimes lethal brain tumor in children has been found to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors.
Tags: BasicResearch, ChildhoodCancer, BrainTumors
When the eye cancer retinoblastoma is diagnosed in racial and ethnic minority children whose families don't have private health insurance, it often takes a more invasive course than in other children, probably because of delays in diagnosis, according to researchers at Dana-Farber/Children's Hospital Cancer Center in Boston.
Tags: ChildhoodCancer, Disparities
Almost two-thirds of children who receive stem cell transplants are readmitted to the hospital within six months, according to researchers at Dana-Farber/Children’s Hospital Cancer Center in Boston.
Tags: ChildhoodCancer, StemCellTransplant
Dana-Farber researchers detail how low doses of interleukin-2 (IL-2) can alleviate chronic graft-versus-host disease (GVHD) and possibly lead to better treatment for other immune disorders.
Tags: BasicResearch, GraftVersusHost
Celebrating the 60th anniversary of the partnership between the Boston Red Sox and the Jimmy Fund during the home opener, the Jimmy Fund Chorus joined former and current players for their major league debut.
Tags: BostonRedSox, JimmyFund
An irregularity within many neuroblastoma cells may indicate whether the tumor is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors.
Tags: BasicResearch, ChildhoodCancer
Would you love a chance to win an authentic Boston Red Sox home jersey signed by star outfielder Jacoby Ellsbury? Then "like" Dana-Farber on Facebook.
Tags: BostonRedSox, JimmyFund
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