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News tagged ‘BasicResearch’ clear

  • Two studies have shed new light on brown fat. In one study, Dr. Bruce Spiegelman reported that his team discovered a hormone, irisin, that is released during exercise and helps turn white fat cells into brown fat cells.

Tags: BasicResearch, PatientEducation

  • New research, led by Dr. Jeffrey Meyerhardt, suggests that late-stage colon cancer patients face a higher risk of cancer recurrence or death if they consume a diet rich in carbohydrates.

Tags: BasicResearch, ColonCancer, Nutrition

  • The Atlantic recognized Dr. Jay Bradner as a "Brave Thinker" for providing open-source access to a molecule he discovered. Dr. Bradner's goal is to expedite the potential development of cancer therapeutics based on the molecule.

Tags: BasicResearch, Honors

  • Several studies published in Nature have identified 74 new genetic risk factors associated with three major cancers: breast, ovarian, and prostate. Dr. Philip Kantoff said it is unclear what this means for patients clinically, but the hope is that it will lead to more sophisticated screening and treatment strategies.

Tags: BasicResearch, BreastCancer, OvarianCancer, ProstateCancer, Genetics, GynecologicCancers

  • Dr. Wayne A. Marasco is researching ways to create a universal flu vaccine that could fight a variety of flu strains. The goal is for the vaccine to work for multiple years and eliminate the need for annual shots.

Tags: BasicResearch, Influenza

  • A study led by Dr. Jane Weeks found that many patients with advanced lung or colon cancer misunderstood the purpose of their chemotherapy treatment. Dr. Weeks said that for these patients to make an informed treatment choice, they need to know that chemotherapy is not curative in most cases.

Tags: BasicResearch, EndOfLife

  • Dr. Bruce Spiegelman reports in the journal Cell that he and his colleagues ave identified a new kind of fat, called "beige fat," that burns calories, rather than stores them. They are now searching for ways to turn on such fat cells in humans to combat obesity and diabetes.

Tags: BasicResearch

  • Dr. Keith Ligon comments on his study that found an unusual mutation in a type of brain tumor in children. The discovery may help to classify, diagnose and guide the treatment of the disease.

Tags: BasicResearch, ChildhoodCancer, BrainTumors

  • A trial led by Mark Kieran, MD, director of pediatric neuro-oncology at Dana-Farber/Children's Hospital Cancer Center found that the drug lonafarnib resulted in weight gain and improved cardiovascular health in children with progeria, a fatal disease causing premature aging. This is an important first step in identifying potential therapies for a disease for which there has been no treatments, Dr. Kieran said.

Tags: BasicResearch

  • A study by researchers at Dana-Farber shows many patients with advanced cancers put false hope in chemotherapy. The study, published in the New England Journal of Medicine, found 69 percent of patients with lung cancer and 81 percent of those with colorectal cancer did not report understanding chemotherapy was not likely to cure their cancer.

Tags: chemotherapy, BasicResearch, EndOfLife

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