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News tagged ‘Genetics’ clear

  • Lung cancer among younger, healthier, and non-smoking individuals "seems to be emerging as its own subtype of lung cancer — one for which new, powerful treatments are needed to make it a livable disease" said Dr. Geoffrey Oxnard, a lung cancer specialist at Dana-Farber Cancer Institute.

Tags: LungCancer, Genetics

  • Dr. Pasi A. Jänne discusses a new study that demonstrates that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

Tags: LungCancer, TargetedTherapy, Genetics

  • MolecularMD has obtained patent rights to technology—jointly owned by researchers at Dana-Farber and the Broad Institute. MolecularMD said it is developing diagnostic assays for use in clinical trials exploring the efficacy of targeted therapies.

Tags: BasicResearch, TargetedTherapy, Genetics

  • Dr. Ursula Matulonis commented on a study that found women with BRCA-1 mutations can reduce their risk of breast and ovarian cancer if they get their ovaries removed by age 35.

Tags: BreastCancer, OvarianCancer, Genetics

  • Several studies published in Nature have identified 74 new genetic risk factors associated with three major cancers: breast, ovarian, and prostate. Dr. Philip Kantoff said it is unclear what this means for patients clinically, but the hope is that it will lead to more sophisticated screening and treatment strategies.

Tags: BasicResearch, BreastCancer, OvarianCancer, ProstateCancer, Genetics, GynecologicCancers

  • Dr. Mehra Golshan said Angelina Jolie's decision to get a double mastectomy might help save lives by raising awareness about the need for genetic testing.

Tags: BreastCancer, Genetics

  • Dr. James Bradner talks about a study he led showing a new way to use JQ1, the molecule that his lab created,to repair damaged hearts after overwhelming stress.

Tags: BasicResearch, Genomics, Genetics

  • Dr. Richard Stone discusses how mutations in a gene involved in the production of white blood cells may improve the diagnosis — and perhaps treatment — of two rare blood cancers.

Tags: Genetics, Leukemia

  • Research has shown that a genetic abnormality behind one illness may also cause other disorders. These shared genetic links may put a person at greater risk for developing related diseases. Dr. Marc Vidal says that because of this interconnectivity, drug companies need to be careful in developing drugs as the treatment for one disease could cause severe side effects.

Tags: Genetics

  • Researchers say they are achieving success in curing the genetic defect that causes some children to be born without immune defenses, according to Dr. David Williams from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

Tags: ImmuneSystem, Genetics

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