Dana-Farber researchers find many men with low-risk, localized prostate cancers can safely choose observation instead of undergoing immediate treatment and have a better quality of life while reducing health care costs.
Tags: ProstateCancer, PopulationScience
A new Dana-Farber study shows a “big picture” view of an overactive B cell receptor (BCR) signaling pathway that drives about one-third of Diffuse Large B-Cell Lymphomas, which could lead to more promising genetic targets for drug development.
Tags: BasicResearch, Lymphoma
The Leukemia & Lymphoma Society and Dana-Farber joined together to establish the Blood Cancer Research Partnership, an innovative program bringing together a network of sites for clinical trial testing of blood cancer therapies in community oncology settings across the country.
Tags: BasicResearch, Leukemia, Lymphoma
Dana-Farber researchers found that combining the immune stimulator GM-CSF with the antibody drug ipilimumab prolonged survival in patients with metastatic melanoma and reduced the incidence of the most serious side effects.
Tags: BasicResearch, Melanoma
Dana-Farber researchers reported that patients with non-small cell lung cancer (NSCLC) whose tumor cells harbored an abnormal ALK gene responded better to targeted therapy than traditional chemotherapy.
Tags: BasicResearch, LungCancer, TargetedTherapy
A Dana-Farber and Harvard School of Public Health study finds that most young women with breast cancer chose to have a mastectomy rather than a surgical procedure that would conserve the breast.
Tags: BasicResearch, BreastCancer
Dana-Farber investigators led a phase 1 trial in which a new oral targeted drug, idelalisib, (GS-1101), showed the potential to stave off the need for additional treatments for relapsed or treatment-resistant CLL.
Tags: BasicResearch, Leukemia
Dr. Frei led Dana-Farber from 1973-1980. During the 1950s and 1960s, Dr. Frei became known as the "father of combination chemotherapy" for demonstrating that treatment with multiple chemotherapy agents could produce lasting remissions in children with acute lymphoblastic leukemia.
A type of low-grade but sometimes lethal brain tumor in children has been found to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors.
Tags: BasicResearch, ChildhoodCancer, BrainTumors
When the eye cancer retinoblastoma is diagnosed in racial and ethnic minority children whose families don't have private health insurance, it often takes a more invasive course than in other children, probably because of delays in diagnosis, according to researchers at Dana-Farber/Children's Hospital Cancer Center in Boston.
Tags: ChildhoodCancer, Disparities
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