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News tagged ‘ImmuneSystem’ clear

  • Dana-Farber/Boston Children's researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated in an international clinical study of a new form of gene therapy.

Tags: ChildhoodCancer, ImmuneSystem, Genetics, Leukemia

  • Dana-Farber scientists report in the Journal of Clinical Investigation they have developed a tumor vaccine based on the patient’s tumor to create a strong and selective immune response in some chronic lymphocytic leukemia patients.

Tags: ImmuneSystem, Leukemia

  • Dana-Farber scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved treatment of arthritis and other autoimmune disorders in people.

Tags: ImmuneSystem

  • A clinical trial for advanced melanoma caused growths to recede or stabilize in half of the participants by blocking a protein interaction that prevents T cells from attacking cancerous cells, reports lead author Stephen Hodi, MD.

Tags: ImmuneSystem, Melanoma

  • In a study that seems to pivot on a paradox, scientists at Dana-Farber Cancer Institute have used an immune system stimulant as an immune system suppressor to treat a common, often debilitating side effect of donor stem cell transplantation in cancer patients.

Tags: BasicResearch, GraftVersusHost, ImmuneSystem

  • A section of the AIDS virus's protein envelope known as the V3 loop and once considered an improbable target for a vaccine now appears to be one of the most promising, according to research authored by Dana-Farber's Ruth Ruprecht, MD, PhD.

Tags: BasicResearch, ImmuneSystem

  • Dana-Farber researchers have found that the basic cause of age-related health decline is malfunctioning telomeres — the end-caps on cells' chromosomes that protect them against DNA damage.

Tags: ImmuneSystem, Genetics

  • Dana-Farber researchers received the grant from the Defense Advanced Research Projects Agency and the Army Research Office to develop a treatment against known, unknown, naturally occurring, or engineered disease-causing pathogens.

Tags: Grants, ImmuneSystem

  • Dana-Farber Cancer Institute scientists identify cells in mice that prevent the immune system from attacking the animals' own cells, protecting them from autoimmune diseases.

Tags: ImmuneSystem

  • The use of monoclonal antibodies to activate an immune-system response to abnormal cells resulted in a significant increase in survival time in patients with metastatic melanoma, report Dana-Farber researchers.

Tags: ImmuneSystem, Melanoma, TranslationalResearch

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