News tagged ‘BasicResearch’ clear
- Dana-Farber scientists have discovered the mechanism behind thalidomide's cancer-killing properties, which could aid development of safer versions and a new class of cancer drugs.
Tags: BasicResearch, MultipleMyeloma, Lymphoma
- Dana-Farber/Harvard Cancer Center researchers receive six Specialized Program of Research Excellence (SPORE) grants, which support research that moves from the laboratory to the clinic.
Tags: BasicResearch, Grants
- Scientists at Dana-Farber Cancer Institute and the University of Colorado Cancer Center report on a gene fusion that spurs the cells to divide rapidly. Treating the cells with a compound that blocks the protein caused the cells to die which may offer a targeted therapy in patients.
Tags: BasicResearch, LungCancer
- A protein that is increased by endurance exercise has been isolated and given to non-exercising mice, in which it turned on genes that promote brain health and encourage the growth of new nerves involved in learning and memory, report scientists from Dana-Farber Cancer Institute and Harvard Medical School.
Tags: BasicResearch, Exercise
- Research led by Dana-Farber/Boston Children's Cancer and Blood Disorders Center reports the discovery of a new genetic target for potential therapy of sickle cell disease.
Tags: BasicResearch, Genetics
- A multi-institutional team of researchers, including those at Dana-Farber, have identified a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.
- Dana-Farber scientists have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, a finding that could serve as a treatment target for castration-resistant prostate cancers.
Tags: BasicResearch, ProstateCancer
- Researchers at Dana-Farber/Children's Hospital Cancer Center have taken the first preliminary steps toward developing a form of gene therapy for sickle cell disease.
- Kornelia Polyak, MD, PhD, was presented with the 2012 AACR Outstanding Investigator Award for Breast Cancer Research at the 35th annual CTRC-AACR San Antonio Breast Cancer Symposium.
Tags: BasicResearch, BreastCancer, Honors
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