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News tagged ‘Genetics’ clear

  • Scientists have catalogued more than 5,000 tumor DNA profiles in a database of genetic abnormalities in cancer, a resource aimed at tailoring highly specific drugs to the particular genetic mutations and other abnormalities that drive a patient's cancer.

Tags: Genomics, TargetedTherapy, Genetics

  • Dana-Farber and Broad Institute researchers for the first time are able to show the past, present, and future of CLL tumors.

Tags: Genetics, Leukemia

  • A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

Tags: LungCancer, TargetedTherapy, Genetics

  • Bruce Johnson, MD, the director of the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute, sorts out the facts about lung cancer and offers simple ways to reduce risk.

Tags: LungCancer, Smoking, TargetedTherapy, Genetics

  • A new study by Dana-Farber researchers shows aspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but has no effect on patients who lack the mutation.

Tags: ColonCancer, Genetics

  • Erica Mayer, MD, MPH, is a breast cancer expert at Dana-Farber. She says there are at least five simple ways women can reduce their risk of getting the disease.

Tags: BreastCancer, Genetics, Prevention

  • Dana-Farber and Brigham and Women's Hospital have launched Profile, one of the most comprehensive cancer research studies to help accelerate the development of personalized treatments for every person with cancer.

Tags: BasicResearch, Genomics, TargetedTherapy, Genetics

  • A new discovery by Jean Zhao, PhD, and colleagues may help physicians predict which tumors are likely to become resistant to a given drug. In the report, published by Nature Medicine, researchers described how they created a genetically engineered mouse model of human breast cancer in which the most frequently occurring breast cancer oncogene, PIK3CA, could be turned on and off.

Tags: BreastCancer, Genomics, TargetedTherapy, Genetics

  • Scientists have unveiled the most comprehensive picture to date of the full genetic blueprint of multiple myeloma. A study of the genomes from 38 cancer samples has yielded insights into the events that lead to this form of blood cancer and could influence the direction of multiple myeloma research.

Tags: MultipleMyeloma, Genetics

  • Dana-Farber researchers have found that the basic cause of age-related health decline is malfunctioning telomeres — the end-caps on cells' chromosomes that protect them against DNA damage.

Tags: ImmuneSystem, Genetics

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