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News tagged ‘Genetics’ clear

  • The discovery of a cancer gene that drives drug resistance in melanomas could lead to more effective drugs for melanoma and other cancers in the future.

Tags: Melanoma, Genetics

  • Prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively, Dana-Farber Cancer Institute researchers report in an online study published by the journal Nature.

Tags: ProstateCancer, Genetics

  • Dana-Farber researchers have found that the basic cause of age-related health decline is malfunctioning telomeres — the end-caps on cells' chromosomes that protect them against DNA damage.

Tags: ImmuneSystem, Genetics

  • Scientists have unveiled the most comprehensive picture to date of the full genetic blueprint of multiple myeloma. A study of the genomes from 38 cancer samples has yielded insights into the events that lead to this form of blood cancer and could influence the direction of multiple myeloma research.

Tags: MultipleMyeloma, Genetics

  • A new discovery by Jean Zhao, PhD, and colleagues may help physicians predict which tumors are likely to become resistant to a given drug. In the report, published by Nature Medicine, researchers described how they created a genetically engineered mouse model of human breast cancer in which the most frequently occurring breast cancer oncogene, PIK3CA, could be turned on and off.

Tags: BreastCancer, Genomics, TargetedTherapy, Genetics

  • Dana-Farber and Brigham and Women's Hospital have launched Profile, one of the most comprehensive cancer research studies to help accelerate the development of personalized treatments for every person with cancer.

Tags: BasicResearch, Genomics, TargetedTherapy, Genetics

  • Erica Mayer, MD, MPH, is a breast cancer expert at Dana-Farber. She says there are at least five simple ways women can reduce their risk of getting the disease.

Tags: BreastCancer, Genetics, Prevention

  • A new study by Dana-Farber researchers shows aspirin therapy can extend the life of colorectal cancer patients whose tumors carry a mutation in a key gene, but has no effect on patients who lack the mutation.

Tags: ColonCancer, Genetics

  • Bruce Johnson, MD, the director of the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute, sorts out the facts about lung cancer and offers simple ways to reduce risk.

Tags: LungCancer, Smoking, TargetedTherapy, Genetics

  • A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

Tags: LungCancer, TargetedTherapy, Genetics

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