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News tagged ‘BasicResearch’ clear

  • Understanding the details of T cell activation opens the way to development of better immune-based therapies against viral infections and cancers.

Tags: BasicResearch

  • Evidence suggests normal cells in bone marrow reduce cancerous cells' ability to undergo apoptosis.

Tags: BasicResearch

  • A combination of two drugs may alleviate radiation sickness in people who have been exposed to high levels of radiation, even when the therapy is given a day after the exposure occurred, according to a study led by scientists from Dana-Farber Cancer Institute and Children's Hospital Boston

Tags: BasicResearch, Radiation

  • Dana-Farber and colleagues from the Cancer Genome Atlas (TCGA) Research Network identified novel mutations in a well-known cancer-causing pathway in lung adenocarcinoma, potentially identifying a greater number of patients with treatable mutations because many potent cancer drugs that target these mutations already exist. Additionally, these findings may expand the number of possible new therapeutic targets for this disease.

Tags: BasicResearch, LungCancer

  • An analysis of two dozen clinical studies finds most adults with poor-risk and intermediate-risk acute myeloid leukemia benefit from allogeneic stem cell transplants.

Tags: BasicResearch, StemCellTransplant, Leukemia

  • A section of the AIDS virus's protein envelope known as the V3 loop and once considered an improbable target for a vaccine now appears to be one of the most promising, according to research authored by Dana-Farber's Ruth Ruprecht, MD, PhD.

Tags: BasicResearch, ImmuneSystem

  • Although it sounds like a case of gender confusion on a molecular scale, the male hormone androgen spurs the growth of some breast tumors in women. In a new study, scientists at Dana-Farber Cancer Institute provide the first details of the cancer cell machinery that carries out the hormone’s relentless growth orders.

Tags: BasicResearch, BreastCancer

  • Scientists at Dana-Farber Cancer Institute and the University of Colorado Cancer Center report on a gene fusion that spurs the cells to divide rapidly. Treating the cells with a compound that blocks the protein caused the cells to die which may offer a targeted therapy in patients.

Tags: BasicResearch, LungCancer

  • Dana-Farber researchers suggest guidelines and provide tools to minimize inconsistencies in collecting and sharing data on interactions between cell proteins.

Tags: BasicResearch

  • Dana-Farber/Harvard Cancer Center researchers receive six Specialized Program of Research Excellence (SPORE) grants, which support research that moves from the laboratory to the clinic.

Tags: BasicResearch, Grants

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