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News tagged ‘Genomics’ clear

  • Dana-Farber scientists identify a genetic flaw that drives some ovarian cancers, which could assist in identifying treatments for ovarian cancer patients.

Tags: Genomics, OvarianCancer, GynecologicCancers

  • Researchers studying a rare, always fatal brain tumor in children have found several molecular alterations that drive the cancer, according to a new study from scientists at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and McGill University. The findings, published in Nature Genetics, identify potential new targets for drug treatments.

Tags: ChildhoodCancer, Genomics, TargetedTherapy, BrainTumors

  • Researchers from the Broad Institute, Dana-Farber Cancer Institute and Weill Cornell Medical College have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of the genetic missteps that underlie the disease.

Tags: Genomics, ProstateCancer

  • Dana-Farber and the Broad Institute researchers have found high levels of the bacterium Fusobacterium in colorectal cancers, a sign that it might contribute to the disease and potentially lead to further research.

Tags: BasicResearch, ColonCancer, Genomics

  • Dana-Farber and Broad Institute researchers have identified two mutations that collectively occur in 71 percent of malignant melanoma tumors. These highly "recurrent" mutations may be the most common mutations in melanoma cells found to date.

Tags: Genomics, Melanoma

  • A team of scientists led by Dana-Farber has created the first molecule able to control gene activity in cancer.

Tags: Genomics, TargetedTherapy

  • Study finds similarities in genetic characteristics of different tumor types, which could lead to common strategies for treating them.

Tags: BasicResearch, Genomics

  • A study by researchers at Dana-Farber Cancer Institute shows that not all doctors are ready to embrace tests that look for hundreds of DNA changes in patients' tumor samples, while others plan to offer this type of cancer gene testing to most of their patients.

Tags: Genomics, TargetedTherapy

  • Newly discovered gene mutations in certain non-small cell and colorectal cancers share similarities with other genetic abnormalities that are known to respond to targeted cancer treatments. This suggests that existing therapies, already approved, could be used to treat patients with these tumors.

Tags: ColonCancer, Genomics, KinaseInhibitor, LungCancer, TargetedTherapy

  • Scientists from Dana-Farber and the Broad Institute have sequenced 25 melanoma tumors and confirmed the long-held suspicion that chronic sun exposure plays a role in skin cancer.

Tags: Genomics, Melanoma

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