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News tagged ‘Genomics’ clear

  • Dana-Farber Cancer Institute researchers have developed a powerful method for charting the positions of key gene-regulating molecules called nucleosomes throughout the human genome.

Tags: Genomics, Melanoma

  • Dana-Farber scientists identify a genetic flaw that drives some ovarian cancers, which could assist in identifying treatments for ovarian cancer patients.

Tags: Genomics, OvarianCancer, GynecologicCancers

  • Scientists have redoubled efforts to disable the mutated cancer gene KRAS, which confers an especially poor prognosis and has proved extraordinarily difficult to target. New research has identified an additional hurdle: inhibiting KRAS can activate a backup pathway in cancer cells that enables them to survive and thrive in the oncogene's absence.

Tags: BasicResearch, Genomics

  • Researchers studying a rare, always fatal brain tumor in children have found several molecular alterations that drive the cancer, according to a new study from scientists at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and McGill University. The findings, published in Nature Genetics, identify potential new targets for drug treatments.

Tags: ChildhoodCancer, Genomics, TargetedTherapy, BrainTumors

  • Scientists will be better able to trace how genetic changes give rise to diseases ranging from cancer to Huntington’s disease with a new map of protein-protein interactions within human cells produced by researchers at the Center for Cancer Systems Biology (CCSB) at Dana-Farber and associates around the world.

Tags: Genomics, Genetics

  • Researchers from the Broad Institute, Dana-Farber Cancer Institute and Weill Cornell Medical College have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of the genetic missteps that underlie the disease.

Tags: Genomics, ProstateCancer

  • Dana-Farber and the Broad Institute researchers have found high levels of the bacterium Fusobacterium in colorectal cancers, a sign that it might contribute to the disease and potentially lead to further research.

Tags: BasicResearch, ColonCancer, Genomics

  • Dana-Farber and Broad Institute researchers have identified two mutations that collectively occur in 71 percent of malignant melanoma tumors. These highly "recurrent" mutations may be the most common mutations in melanoma cells found to date.

Tags: Genomics, Melanoma

  • A team of scientists led by Dana-Farber has created the first molecule able to control gene activity in cancer.

Tags: Genomics, TargetedTherapy

  • Study finds similarities in genetic characteristics of different tumor types, which could lead to common strategies for treating them.

Tags: BasicResearch, Genomics

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