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News tagged ‘Genomics’ clear

  • Dana-Farber and the Broad Institute researchers have found high levels of the bacterium Fusobacterium in colorectal cancers, a sign that it might contribute to the disease and potentially lead to further research.

Tags: BasicResearch, ColonCancer, Genomics

  • Dana-Farber and Broad Institute researchers have identified two mutations that collectively occur in 71 percent of malignant melanoma tumors. These highly "recurrent" mutations may be the most common mutations in melanoma cells found to date.

Tags: BasicResearch, Genomics, Melanoma

  • A team of scientists led by Dana-Farber has created the first molecule able to control gene activity in cancer.

Tags: Genomics, TargetedTherapy

  • Study finds similarities in genetic characteristics of different tumor types, which could lead to common strategies for treating them.

Tags: BasicResearch, Genomics

  • Newly discovered gene mutations in certain non-small cell and colorectal cancers share similarities with other genetic abnormalities that are known to respond to targeted cancer treatments. This suggests that existing therapies, already approved, could be used to treat patients with these tumors.

Tags: ColonCancer, Genomics, KinaseInhibitor, LungCancer, TargetedTherapy

  • Scientists from Dana-Farber and the Broad Institute have sequenced 25 melanoma tumors and confirmed the long-held suspicion that chronic sun exposure plays a role in skin cancer.

Tags: Genomics, Melanoma

  • The Cancer Genome Atlas Research Network has identified a large number and variety of DNA alterations in squamous cell lung cancer tumors, which could serve as potential therapeutic targets for treating the second most common type of lung cancer.

Tags: Genomics, LungCancer, TargetedTherapy

  • A team led by Dana-Farber scientists has developed a more human-like mouse model of cancer they say will aid the search for cancer-causing genes and improve the predictive value of laboratory drug testing.

Tags: Genomics, Genetics

  • The search for cancer genes is increasingly a matter of molecular "To Tell the Truth," as scientists seek to distinguish genes actually involved in the disease from those that are imposters.

Tags: Genomics, BrainTumors

  • A genetic survey of glioblastoma reveals a variety of broken, missing, and overactive genes, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

Tags: BasicResearch, Genomics, BrainTumors

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