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News tagged ‘TargetedTherapy’ clear

  • A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

Tags: LungCancer, TargetedTherapy, Genetics

  • A team of scientists led by Dana-Farber has created the first molecule able to control gene activity in cancer.

Tags: Genomics, TargetedTherapy

  • In a demonstration that even some of the most hard-to-treat tumors may one day succumb to therapies aimed at molecular "weak points," researchers at Dana-Farber report the first instance in which metastatic melanoma has been driven into remission by a targeted therapy.

Tags: Melanoma, TargetedTherapy

  • A study by researchers at Dana-Farber Cancer Institute shows that not all doctors are ready to embrace tests that look for hundreds of DNA changes in patients' tumor samples, while others plan to offer this type of cancer gene testing to most of their patients.

Tags: Genomics, TargetedTherapy

  • Newly discovered gene mutations in certain non-small cell and colorectal cancers share similarities with other genetic abnormalities that are known to respond to targeted cancer treatments. This suggests that existing therapies, already approved, could be used to treat patients with these tumors.

Tags: ColonCancer, Genomics, KinaseInhibitor, LungCancer, TargetedTherapy

  • Regorafenib was found to reduce the risk of disease progression or death by more than 70 percent in patients whose tumors had become resistant to Gleevec and Sutent.

Tags: DrugResistance, Sarcoma, TargetedTherapy

  • A targeted drug that reduces blood flow to tumors prolonged the survival of patients with advanced stomach cancer after standard treatments failed, according to results of large multicenter clinical trial led by scientists at Dana-Farber Cancer Institute.

Tags: chemotherapy, TargetedTherapy

  • The Cancer Genome Atlas Research Network has identified a large number and variety of DNA alterations in squamous cell lung cancer tumors, which could serve as potential therapeutic targets for treating the second most common type of lung cancer.

Tags: Genomics, LungCancer, TargetedTherapy

  • A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report investigators at Dana-Farber who led the worldwide clinical trial.

Tags: KinaseInhibitor, Sarcoma, TargetedTherapy

  • A new oral drug caused dramatic shrinkage of a patient's rare, aggressive form of soft-tissue cancer that was driven by an abnormally activated protein, physician-scientists from Dana-Farber Cancer Institute report.

Tags: Sarcoma, TargetedTherapy

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