News tagged ‘TargetedTherapy’ clear
- In a demonstration that even some of the most hard-to-treat
tumors may one day succumb to therapies aimed at molecular "weak
points," researchers at Dana-Farber report the first instance in which
metastatic melanoma has been driven into remission by a targeted
therapy.
Tags: Melanoma, TargetedTherapy
Newly discovered gene mutations in certain non-small cell and colorectal cancers share similarities with other genetic abnormalities that are known to respond to targeted cancer treatments. This suggests that existing therapies, already approved, could be used to treat patients with these tumors.
Tags: ColonCancer, Genomics, KinaseInhibitor, LungCancer, TargetedTherapy
Regorafenib was found to reduce the risk of disease progression or death by more than 70 percent in patients whose tumors had become resistant to Gleevec and Sutent.
Tags: DrugResistance, Sarcoma, TargetedTherapy
The Cancer Genome Atlas Research Network has identified a large number and variety of DNA alterations in squamous cell lung cancer tumors, which could serve as potential therapeutic targets for treating the second most common type of lung cancer.
Tags: Genomics, LungCancer, TargetedTherapy
- A new targeted drug demonstrated its ability to control metastatic gastrointestinal stromal tumor, an uncommon and life-threatening form of sarcoma, after the disease had become resistant to all existing therapies, report investigators at Dana-Farber who led the worldwide clinical trial.
Tags: KinaseInhibitor, Sarcoma, TargetedTherapy
- A new oral drug caused dramatic shrinkage of a patient's rare,
aggressive form of soft-tissue cancer that was driven by an abnormally
activated protein, physician-scientists from Dana-Farber Cancer
Institute report.
Tags: Sarcoma, TargetedTherapy
The Massachusetts Life Sciences Center has awarded Dana-Farber Cancer Institute a $10 million grant to support the expansion of its pioneering cancer imaging research program with a new imaging facility which will support more rapid assessment of therapies and play a key role in the delivery of personalized medicine.
Tags: BasicResearch, Grants, TargetedTherapy, Imaging
Scientists from Dana-Farber and the Broad Institute have identified two DNA mutations that appear to drive about 15 percent of meningiomas, a finding that could lead to the first effective drug treatments for the brain tumor.
Tags: BasicResearch, TargetedTherapy, BrainTumors
Bruce Johnson, MD, the director of the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute, sorts out the facts about lung cancer and offers simple ways to reduce risk.
Tags: LungCancer, Smoking, TargetedTherapy, Genetics
A multi-institutional team of researchers has published a study that demonstrates a novel therapy works against solid tumors. It is the first targeted and programmed nanomedicine to enter human clinical studies.
Tags: TargetedTherapy, TranslationalResearch
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