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News tagged ‘Genetics’ clear

  • Discovery of gene activity signature suggests patients with breast tumors resistant to commonly used chemotherapy drugs could be treated instead with more effective therapies.

Tags: Genetics

  • Dana-Farber/Boston Children's researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated in an international clinical study of a new form of gene therapy.

Tags: ChildhoodCancer, ImmuneSystem, Genetics, Leukemia

  • A gene whose existence was detected only a couple of years ago may increase women's risk of breast cancer when inherited in a mutated form, and may contribute to prostate cancer as well, researchers at Dana-Farber and colleagues in Finland report in a new study.

Tags: BreastCancer, Genomics, Genetics

  • The Joint Center for Cancer Precision Medicine, a collaborative initiative among Dana-Farber Cancer Institute, Brigham and Women’s Hospital, Boston Children’s Hospital, and the Broad Institute of MIT and Harvard, has been established to create “precision medicine treatment pathways” for patients with advanced cancers and to speed the development of personalized therapies.

Tags: Genomics, Partnerships, TargetedTherapy, Genetics

  • Scientists have catalogued more than 5,000 tumor DNA profiles in a database of genetic abnormalities in cancer, a resource aimed at tailoring highly specific drugs to the particular genetic mutations and other abnormalities that drive a patient's cancer.

Tags: Genomics, TargetedTherapy, Genetics

  • The most comprehensive genetic study to date of the blood cancer multiple myeloma has revealed that the genetic landscape of the disease may be more complicated than previously thought.

Tags: BasicResearch, MultipleMyeloma, Genetics

  • Researchers at Dana-Farber have developed a tool to help predict how a patient’s tumor is likely to behave and which of several possible treatments is most likely to be effective.

Tags: BreastCancer, Genetics

  • A team led by Dana-Farber scientists has developed a more human-like mouse model of cancer they say will aid the search for cancer-causing genes and improve the predictive value of laboratory drug testing.

Tags: Genomics, Genetics

  • Scanning the DNA of nearly 5,000 tumor samples, a team led by scientists at Dana-Farber Cancer Institute and the Broad Institute has identified 140 regions of scrambled genetic code believed to contain many undiscovered cancer genes.

Tags: Genomics, Genetics

  • Dana-Farber scientists show a previously unsuspected gene can also influence transcription factors and potentially disable tumor cells.

Tags: ColonCancer, Genetics

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