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News tagged ‘LungCancer’ clear

  • A collaborative study involving Dana-Farber researchers has unearthed a variety of genetic alterations in lung tumors, more than doubling the number already linked to the disease.

Tags: Genomics, LungCancer

  • Collaborating scientists in Boston and North Carolina have found that a particular gene can block key steps of the lung cancer process in mice. The researchers report in the journal Nature that LKB1 is not only a "tumor-suppressor" gene for non-small cell lung cancer in mice, it also may be more powerful than other, better-known suppressors.

Tags: BasicResearch, LungCancer

  • An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute, has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva.

Tags: LungCancer

  • The Cancer Genome Atlas Research Network has identified a large number and variety of DNA alterations in squamous cell lung cancer tumors, which could serve as potential therapeutic targets for treating the second most common type of lung cancer.

Tags: Genomics, LungCancer, TargetedTherapy

  • Newly discovered gene mutations in certain non-small cell and colorectal cancers share similarities with other genetic abnormalities that are known to respond to targeted cancer treatments. This suggests that existing therapies, already approved, could be used to treat patients with these tumors.

Tags: ColonCancer, Genomics, KinaseInhibitor, LungCancer, TargetedTherapy

  • A study 10 years ago discovered a gene mutation that could be treated by a drug that was on the market for something else and changed the way lung cancer patients are treated. It was the start of the era of precision medicine in lung cancer and transformed treatment of the disease.

Tags: EGFR, LungCancer, TargetedTherapy

  • There's never a bad time to stop smoking. Bruce Johnson, MD, explains the benefits of quitting smoking and offers tips to get started.

Tags: LungCancer, PatientEducation, PatientSupport, Prevention

  • Researchers have halted non-small cell lung tumors resistant to Iressa and Tarceva with a newly constructed compound that may also have fewer side effects.

Tags: DrugResistance, LungCancer

  • A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

Tags: LungCancer, TargetedTherapy, Genetics

  • Scientists at Dana-Farber Cancer Institute and the University of Colorado Cancer Center report on a gene fusion that spurs the cells to divide rapidly. Treating the cells with a compound that blocks the protein caused the cells to die which may offer a targeted therapy in patients.

Tags: BasicResearch, LungCancer

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