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News tagged ‘Genomics’ clear

  • Findings by Dana-Farber scientists and others show the disarray in the on-off mechanism – known as methylation – is one of the defining characteristics of cancer and helps tumors adapt to changing circumstances.

Tags: BasicResearch, Genomics

  • Scientists from Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive "triple negative" breast cancers and certain ovarian cancers will likely respond to platinum-based chemotherapies.

Tags: BasicResearch, BreastCancer, Genomics, OvarianCancer, GynecologicCancers

  • Dr. Gimelbrant is mapping gene activation to better understand the mechanisms essential for gene silencing. His findings could lead to the design of highly customized cancer treatments.

Tags: BasicResearch, Genomics

  • Levi Garraway, MD, PhD, has been named as a recipient of the prestigious Paul Marks Prize for Cancer Research, which recognizes promising investigators aged 45 or younger who are advancing the field of cancer research.

Tags: Genomics, Honors, Genetics

  • Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center, using CRISPR-based gene editing techniques, have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell disease (SCD), according to a study published in the journal Nature.

Tags: Genomics, Genetics

  • In a study published in the journal Nature, researchers at Dana-Farber Cancer Institute and an international team of associates used a technique involving viral proteins to prioritize which of the many mutated genes in tumor cells are likely involved in cancer and which are mere bystanders.

Tags: BasicResearch, Genomics

  • Immunotherapy, genomic profiling, and investigating game-changing drug therapies topped the list of most important cancer research and clinical developments at Dana-Farber Cancer Institute in 2014.

Tags: EGFR, Genomics, LungCancer, OvarianCancer, ProstateCancer, Lymphoma, Immunotherapy

  • First study of the genomic composition of prostate cancer shows many patients have gene mutations that can be targeted with existing or potential drugs.

Tags: Genomics, ProstateCancer, TargetedTherapy

  • A gene whose existence was detected only a couple of years ago may increase women's risk of breast cancer when inherited in a mutated form, and may contribute to prostate cancer as well, researchers at Dana-Farber and colleagues in Finland report in a new study.

Tags: BreastCancer, Genomics, Genetics

  • Dana-Farber researchers and colleagues completed a comprehensive genomic analysis of cervical cancer, identifying recurrent genetic mutations not previously found and shedding light on the role human papillomavirus (HPV) plays in the development of the disease.

Tags: BasicResearch, CervicalCancer, Genomics

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