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News tagged ‘Melanoma’ clear

  • F. Stephen Hodi, MD, and colleagues report the immunotherapy drug nivolumab continues to show long-term effectiveness in treating metastatic melanoma, achieving a three-year survival rate of 41 percent against the deadly skin cancer.

Tags: Melanoma, Immunotherapy

  • Dana-Farber scientists have developed a technique that can cause white blood cells trained to attack tumors to survive in patients’ bloodstreams for well over a year, and, in some cases, without the need of other, highly toxic treatments.

Tags: Melanoma

  • Scientists from Dana-Farber and the Broad Institute have sequenced 25 melanoma tumors and confirmed the long-held suspicion that chronic sun exposure plays a role in skin cancer.

Tags: Genomics, Melanoma

  • Dana-Farber researchers report in the New England Journal of Medicine that treating advanced melanoma patients initially with the combination of the immunotherapy drugs nivolumab and ipilimumab achieves a much higher response rate than treatment with ipilimumab alone.

Tags: Melanoma, Immunotherapy

  • A clinical trial for advanced melanoma caused growths to recede or stabilize in half of the participants by blocking a protein interaction that prevents T cells from attacking cancerous cells, reports lead author Stephen Hodi, MD.

Tags: ImmuneSystem, Melanoma

  • In a demonstration that even some of the most hard-to-treat tumors may one day succumb to therapies aimed at molecular "weak points," researchers at Dana-Farber report the first instance in which metastatic melanoma has been driven into remission by a targeted therapy.

Tags: Melanoma, TargetedTherapy

  • Dana-Farber and Broad Institute researchers have identified two mutations that collectively occur in 71 percent of malignant melanoma tumors. These highly "recurrent" mutations may be the most common mutations in melanoma cells found to date.

Tags: Genomics, Melanoma

  • The discovery of a cancer gene that drives drug resistance in melanomas could lead to more effective drugs for melanoma and other cancers in the future.

Tags: Melanoma, Genetics

  • ABC News' Sam Donaldson shared his experience as a melanoma patient during his keynote speech at the Dana-Farber Cancer Institute Joint Visiting Committee Symposium dinner Nov. 15.

Tags: Melanoma

  • Dana-Farber Cancer Institute researchers have developed a powerful method for charting the positions of key gene-regulating molecules called nucleosomes throughout the human genome.

Tags: Genomics, Melanoma

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