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News tagged ‘BasicResearch’ clear

  • Scientists at Dana-Farber Cancer Institute and the University of Colorado Cancer Center report on a gene fusion that spurs the cells to divide rapidly. Treating the cells with a compound that blocks the protein caused the cells to die which may offer a targeted therapy in patients.

Tags: BasicResearch, LungCancer

  • A protein that is increased by endurance exercise has been isolated and given to non-exercising mice, in which it turned on genes that promote brain health and encourage the growth of new nerves involved in learning and memory, report scientists from Dana-Farber Cancer Institute and Harvard Medical School.

Tags: BasicResearch, Exercise

  • Research led by Dana-Farber/Boston Children's Cancer and Blood Disorders Center reports the discovery of a new genetic target for potential therapy of sickle cell disease.

Tags: BasicResearch, Genetics

  • A multi-institutional team of researchers, including those at Dana-Farber, have identified a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.

Tags: BasicResearch

  • Dana-Farber scientists find when given together, two orally available experimental drugs – sapacitabine and seliciclib – worked together to elicit antitumor effects in patients with incurable BRCA-deficient cancers.

Tags: BasicResearch, BreastCancer, PancreaticCancer, GynecologicCancers

  • Dana-Farber scientists have discovered a molecular switch that enables advanced prostate cancers to spread without stimulation by male hormones, a finding that could serve as a treatment target for castration-resistant prostate cancers.

Tags: BasicResearch, ProstateCancer

  • Researchers at Dana-Farber/Children's Hospital Cancer Center have taken the first preliminary steps toward developing a form of gene therapy for sickle cell disease.

Tags: BasicResearch

  • Kornelia Polyak, MD, PhD, was presented with the 2012 AACR Outstanding Investigator Award for Breast Cancer Research at the 35th annual CTRC-AACR San Antonio Breast Cancer Symposium.

Tags: BasicResearch, BreastCancer, Honors

  • Scientists at Dana-Farber Cancer Institute have isolated a previously unknown protein in muscles that spurs their growth and increased power following resistance exercise. They suggest that artificially raising the protein’s levels might someday help prevent muscle loss caused by cancer, prolonged inactivity in hospital patients, and aging.

Tags: BasicResearch, Exercise

  • Dana-Farber Cancer Institute researchers report findings from a nationwide study that suggest that advanced lung or colorectal cancer patients are frequently mistaken in their beliefs that chemotherapy can cure their disease.

Tags: BasicResearch, EndOfLife

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