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News tagged ‘Genetics’ clear

  • Dana-Farber researchers have found that the basic cause of age-related health decline is malfunctioning telomeres — the end-caps on cells' chromosomes that protect them against DNA damage.

Tags: ImmuneSystem, Genetics

  • Prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively, Dana-Farber Cancer Institute researchers report in an online study published by the journal Nature.

Tags: ProstateCancer, Genetics

  • The discovery of a cancer gene that drives drug resistance in melanomas could lead to more effective drugs for melanoma and other cancers in the future.

Tags: Melanoma, Genetics

  • Discovery of gene activity signature suggests patients with breast tumors resistant to commonly used chemotherapy drugs could be treated instead with more effective therapies.

Tags: Genetics

  • Nine-fold higher pancreatic cancer risk suggests people with this genetic syndrome should be closely monitored.

Tags: ProstateCancer, Genetics

  • Deprived of androgen hormones, the receptor finds an alternative genetic pathway to continue growth of prostate cancer cells. An understanding of this behavior could lead to new therapies targeting specific genes.

Tags: BasicResearch, ProstateCancer, Genetics

  • Researchers working in genomics and molecular biology have demonstrated that a surplus of a gene known as GOLPH3 can spur cancer cell growth.

Tags: Genomics, Genetics

  • Dana-Farber researchers have identified previously unknown mutations in a single gene in 8 percent of neuroblastomas, which account for around 15 percent of all childhood cancer deaths.

Tags: BasicResearch, Genetics

  • Dana-Farber scientists show a previously unsuspected gene can also influence transcription factors and potentially disable tumor cells.

Tags: ColonCancer, Genetics

  • A team led by Dana-Farber scientists has developed a more human-like mouse model of cancer they say will aid the search for cancer-causing genes and improve the predictive value of laboratory drug testing.

Tags: Genomics, Genetics

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