News tagged ‘Genomics’ clear
Newly discovered gene mutations in certain non-small cell and colorectal cancers share similarities with other genetic abnormalities that are known to respond to targeted cancer treatments. This suggests that existing therapies, already approved, could be used to treat patients with these tumors.
Tags: ColonCancer, Genomics, KinaseInhibitor, LungCancer, TargetedTherapy
Jessie M. English, PhD, has been appointed the head of Research of the Belfer Institute for Applied Cancer Science at Dana-Farber. The Belfer Institute offers the full array of innovative drug discovery capabilities, from the identification of cancer-causing genetic mutations to the validation and selection of new drug targets.
Tags: Genomics, LungCancer, TargetedTherapy, TranslationalResearch
Scientists from Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive "triple negative" breast cancers and certain ovarian cancers will likely respond to platinum-based chemotherapies.
Tags: BasicResearch, BreastCancer, Genomics, OvarianCancer, GynecologicCancers
Dana-Farber scientists and colleagues have published results from the Cancer Cell Line Encyclopedia, a resource that marries cancer genome data with predictors of drug responses. This information could refine cancer clinical trials and future treatments.
Tags: BasicResearch, Genomics
- Scientists from Dana-Farber and the Broad Institute have sequenced 25 melanoma tumors and confirmed the long-held suspicion that chronic sun exposure plays a role in skin cancer.
Tags: Genomics, Melanoma
In one of the largest breast cancer sequencing efforts to date, scientists from Dana-Farber and their colleagues have discovered surprising alterations in genes that were not previously associated with breast cancer.
Tags: BasicResearch, BreastCancer, Genomics
Dana-Farber researchers are studying melanoma tumors' microenvironments to better understand how some melanoma continue to grow and survive despite the presence of anti-cancer drugs.
Tags: BasicResearch, Genomics, Melanoma
Dana-Farber/Children's Hospital Cancer Center researchers have linked genetic mutations to each of the four recognized subtypes of medulloblastoma, the most common malignant brain tumor of children.
Tags: BasicResearch, ChildhoodCancer, Genomics, BrainTumors
In a study published in the journal Nature, researchers at Dana-Farber Cancer Institute and an international team of associates used a technique involving viral proteins to prioritize which of the many mutated genes in tumor cells are likely involved in cancer and which are mere bystanders.
Tags: BasicResearch, Genomics
- The Cancer Genome Atlas Research Network has identified a large number and variety of DNA alterations in squamous cell lung cancer tumors, which could serve as potential therapeutic targets for treating the second most common type of lung cancer.
Tags: Genomics, LungCancer, TargetedTherapy
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