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News tagged ‘Genetics’ clear

  • Dana-Farber and Brigham and Women's Hospital have launched Profile, one of the most comprehensive cancer research studies to help accelerate the development of personalized treatments for every person with cancer.

Tags: BasicResearch, Genomics, TargetedTherapy, Genetics

  • A new discovery by Jean Zhao, PhD, and colleagues may help physicians predict which tumors are likely to become resistant to a given drug. In the report, published by Nature Medicine, researchers described how they created a genetically engineered mouse model of human breast cancer in which the most frequently occurring breast cancer oncogene, PIK3CA, could be turned on and off.

Tags: BreastCancer, Genomics, TargetedTherapy, Genetics

  • Scientists have unveiled the most comprehensive picture to date of the full genetic blueprint of multiple myeloma. A study of the genomes from 38 cancer samples has yielded insights into the events that lead to this form of blood cancer and could influence the direction of multiple myeloma research.

Tags: MultipleMyeloma, Genetics

  • Dana-Farber researchers have found that the basic cause of age-related health decline is malfunctioning telomeres — the end-caps on cells' chromosomes that protect them against DNA damage.

Tags: ImmuneSystem, Genetics

  • Prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively, Dana-Farber Cancer Institute researchers report in an online study published by the journal Nature.

Tags: ProstateCancer, Genetics

  • The discovery of a cancer gene that drives drug resistance in melanomas could lead to more effective drugs for melanoma and other cancers in the future.

Tags: Melanoma, Genetics

  • Discovery of gene activity signature suggests patients with breast tumors resistant to commonly used chemotherapy drugs could be treated instead with more effective therapies.

Tags: Genetics

  • Nine-fold higher pancreatic cancer risk suggests people with this genetic syndrome should be closely monitored.

Tags: ProstateCancer, Genetics

  • Deprived of androgen hormones, the receptor finds an alternative genetic pathway to continue growth of prostate cancer cells. An understanding of this behavior could lead to new therapies targeting specific genes.

Tags: BasicResearch, ProstateCancer, Genetics

  • Researchers working in genomics and molecular biology have demonstrated that a surplus of a gene known as GOLPH3 can spur cancer cell growth.

Tags: Genomics, Genetics

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