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News tagged ‘BasicResearch’ clear

  • Dana-Farber researchers suggest guidelines and provide tools to minimize inconsistencies in collecting and sharing data on interactions between cell proteins.

Tags: BasicResearch

  • Dana-Farber scientists find when given together, two orally available experimental drugs – sapacitabine and seliciclib – worked together to elicit antitumor effects in patients with incurable BRCA-deficient cancers.

Tags: BasicResearch, BreastCancer, OvarianCancer, PancreaticCancer, GynecologicCancers

  • In prostate cancer patients with a certain genetic variant, a high level of selenium in the blood was associated with a two-fold greater risk of poorer outcomes than men with the lowest amounts of selenium.

Tags: BasicResearch, ProstateCancer

  • Dana-Farber scientists have identified a trigger point on a naturally occurring "death protein" that may lead to designer drugs that force cancer cells to commit suicide.

Tags: BasicResearch

  • Scientists have for the first time partially reversed age-related degeneration in mice, using a strategy that might one day treat conditions such as rare genetic premature aging syndromes.

Tags: BasicResearch

  • Researchers report that these antibodies have the potential for use in combination with other treatments to prevent or treat certain types of avian and seasonal flu.

Tags: BasicResearch

  • Dana-Farber scientists found that pancreatic cancer cells' growth and spread are fueled by an unusual metabolic pathway that someday might be blocked with targeted drugs to control the deadly cancer.

Tags: BasicResearch, PancreaticCancer, TargetedTherapy

  • A type of low-grade but sometimes lethal brain tumor in children has been found to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors.

Tags: BasicResearch, ChildhoodCancer, BrainTumors

  • Researchers at Dana-Farber have identified a long-sought "master switch" in mice for the production of brown fat, a type of adipose tissue that generates heat and counters obesity caused by overeating.

Tags: BasicResearch

  • Dana-Farber researchers have engineered mouse and human cells to produce a natural energy-burning fat that counteracts obesity. If such a strategy can be developed for use in people, it could open a novel approach to treating obesity and diabetes.

Tags: BasicResearch

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