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News tagged ‘ChildhoodCancer’ clear

  • Physicians who inform parents of children with cancer about the likely course of the disease can provide hope, even when the child's prognosis is poor, according to a Dana-Farber Cancer Institute study presented at a press briefing at the American Society of Clinical Oncology annual meeting.

Tags: ChildhoodCancer

  • An irregularity within many neuroblastoma cells may indicate whether the tumor is vulnerable to a new class of anti-cancer drugs known as BET bromodomain inhibitors.

Tags: ChildhoodCancer

  • Researchers found a way of differentiating angiocentric gliomas from other low-grade pediatric brain tumors and developed a pathological test that will help children avoid unnecessary and potentially damaging additional therapies.

Tags: BasicResearch, ChildhoodCancer, BrainTumors

  • Clinical genomic sequencing is feasible in pediatric oncology and can be used to recommend therapy or pinpoint diagnosis in children with solid tumors according to research led by Dana-Farber/Boston Children's Cancer and Blood Disorders Center. The findings, published in JAMA Oncology, represent a significant step in making precision medicine available to children with cancer.

Tags: ChildhoodCancer, TargetedTherapy, Genetics

  • A "watch and wait" strategy reduces the need for unnecessary chemo in young girls, which can lead to secondary cancers and other health issues later in life.

Tags: ChildhoodCancer, OvarianCancer, PatientEducation

  • Pediatric patients with B-precursor acute lymphoblastic leukemia who are likely to relapse after chemotherapy treatment can reduce those odds by receiving additional courses of chemotherapy, according to research by Dana-Farber/Children's Hospital Cancer Center investigators.

Tags: chemotherapy, ChildhoodCancer, Leukemia

  • Dana-Farber/Boston Children's researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated in an international clinical study of a new form of gene therapy.

Tags: ChildhoodCancer, ImmuneSystem, Genetics, Leukemia

  • Dana-Farber/Children's Hospital Cancer Center researchers have linked genetic mutations to each of the four recognized subtypes of medulloblastoma, the most common malignant brain tumor of children.

Tags: BasicResearch, ChildhoodCancer, Genomics, BrainTumors

  • Children with acute lymphoblastic leukemia (ALL), the most common form of pediatric cancer, can safely receive intravenous infusions of a reformulated mainstay of chemotherapy that has been delivered via painful intramuscular injection for more than 40 years, research suggests.

Tags: chemotherapy, ChildhoodCancer, Leukemia

  • Almost 90 percent of children treated for low-grade gliomas are alive 20 years later and few die from the tumor as adults. However, children whose treatment included radiation had significantly lower long-term survival rates.

Tags: ChildhoodCancer, Radiation, BrainTumors

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