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News tagged ‘Genetics’ clear

  • The most comprehensive genetic study to date of the blood cancer multiple myeloma has revealed that the genetic landscape of the disease may be more complicated than previously thought.

Tags: BasicResearch, MultipleMyeloma, Genetics

  • Researchers at Dana-Farber have developed a tool to help predict how a patient’s tumor is likely to behave and which of several possible treatments is most likely to be effective.

Tags: BreastCancer, Genetics

  • A team led by Dana-Farber scientists has developed a more human-like mouse model of cancer they say will aid the search for cancer-causing genes and improve the predictive value of laboratory drug testing.

Tags: Genomics, Genetics

  • Scanning the DNA of nearly 5,000 tumor samples, a team led by scientists at Dana-Farber Cancer Institute and the Broad Institute has identified 140 regions of scrambled genetic code believed to contain many undiscovered cancer genes.

Tags: Genomics, Genetics

  • A study led by Pasi Jänne, MD, PhD, found that an experimental drug targeted to the resistance mutation is highly active in patients with EGFR-positive non-small cell lung cancer (NSCLC) when the disease progressed during treatment with front-line inhibitor drugs.

Tags: LungCancer, Genetics

  • An overwhelming majority of people with incurable cancer want to hear findings from DNA sequencing of their own tumors and normal cells, and to learn how those results may affect their health and treatment options, Dana-Farber Cancer Institute scientists report.

Tags: Genetics

  • Dana-Farber scientists show a previously unsuspected gene can also influence transcription factors and potentially disable tumor cells.

Tags: ColonCancer, Genetics

  • Dana-Farber researchers have identified previously unknown mutations in a single gene in 8 percent of neuroblastomas, which account for around 15 percent of all childhood cancer deaths.

Tags: BasicResearch, Genetics

  • Scientists will be better able to trace how genetic changes give rise to diseases ranging from cancer to Huntington’s disease with a new map of protein-protein interactions within human cells produced by researchers at the Center for Cancer Systems Biology (CCSB) at Dana-Farber and associates around the world.

Tags: Genomics, Genetics

  • A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

Tags: LungCancer, TargetedTherapy, Genetics

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