News tagged ‘Genomics’ clear
- Dana-Farber and Broad Institute researchers have identified two mutations that collectively occur in 71 percent of malignant melanoma tumors. These highly "recurrent" mutations may be the most common mutations in melanoma cells found to date.
Tags: BasicResearch, Genomics, Melanoma
- Dana-Farber and the Broad Institute researchers have found high levels of the bacterium Fusobacterium in colorectal cancers, a sign that it might contribute to the disease and potentially lead to further research.
Tags: BasicResearch, ColonCancer, Genomics
- Researchers from the Broad Institute, Dana-Farber Cancer Institute and
Weill Cornell Medical College have laid bare the full genetic blueprint
of multiple prostate tumors, uncovering alterations that have never
before been detected and offering a deep view of the genetic missteps
that underlie the disease.
Tags: Genomics, ProstateCancer
- Dana-Farber Cancer Institute researchers have developed a powerful
method for charting the positions of key gene-regulating molecules
called nucleosomes throughout the human genome.
Tags: Genomics, Melanoma
- A new discovery by Jean Zhao, PhD, and colleagues may help physicians predict which tumors are likely to become resistant to a given drug. In the report, published by Nature Medicine, researchers described how they created a genetically engineered mouse model of human breast cancer in which the most frequently occurring breast cancer oncogene, PIK3CA, could be turned on and off.
Tags: BreastCancer, Genomics, TargetedTherapy, Genetics
- A study by scientists at Dana-Farber Cancer Institute, the Broad Institute, and other research centers, may offer clues to why rates of esophageal adenocarcinomas (EACs) have risen so sharply. The findings, in Nature Genetics, point to an array of abnormal genes and proteins that may be lynchpins of EAC cell growth and therefore serve as targets for new therapies.
Tags: BasicResearch, Genomics, TargetedTherapy
- Researchers working in genomics and molecular biology have demonstrated that a surplus of a gene known as GOLPH3 can spur cancer cell growth.
Tags: Genomics, Genetics
- Dana-Farber scientists have linked genetic variants to the regulation of genes involved in breast cancer, including four genes not previously implicated in breast cancer, shedding new insights into the biology of breast cancer.
Tags: BasicResearch, BreastCancer, Genomics
- Scientists at Dana-Farber Cancer Institute have shown in a laboratory
study that revving up a crucial set of muscle genes counteracts the
damage caused by a form of muscular dystrophy.
Tags: Genomics, Genetics
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