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News tagged ‘BasicResearch’ clear

  • Genetic specialists at Dana-Farber/Children’s Hospital Cancer Center (DF/CHCC) are recommending that children being treated for sarcoma should be offered genetic counseling for Li-Fraumeni syndrome, a rare condition that greatly raises a person’s risk of developing additional cancers

Tags: BasicResearch, Genomics, Sarcoma

  • Study finds delay of more than six weeks between surgery and radiation makes local recurrence more likely, and could have implications for younger women's risk of recurrence.

Tags: BasicResearch

  • Dana-Farber Cancer Institute and Children's Hospital Boston researchers have identified a protein that could be a powerful treatment target for sickle cell anemia, a significant global health problem, one that affects between 75,000 and 100,000 people in the United States alone.

Tags: BasicResearch

  • Research led by Dana-Farber/Boston Children's Cancer and Blood Disorders Center reports the discovery of a new genetic target for potential therapy of sickle cell disease.

Tags: BasicResearch, Genetics

  • Scientists from Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive "triple negative" breast cancers and certain ovarian cancers will likely respond to platinum-based chemotherapies.

Tags: BasicResearch, BreastCancer, Genomics, OvarianCancer, GynecologicCancers

  • Dr. Gimelbrant is mapping gene activation to better understand the mechanisms essential for gene silencing. His findings could lead to the design of highly customized cancer treatments.

Tags: BasicResearch, Genomics

  • Scientists at Dana-Farber demonstrate that it’s possible, early in a tumor’s growth, to identify cancer genes that endow the tumor with the ability to metastasize. This is an important step toward developing prognostic tests for identifying early-stage tumors that are likely to spread and can be treated accordingly.

Tags: BasicResearch, Melanoma

  • Researchers at Dana-Farber and Children's Hospital Boston have shown that changes in the structure of DNA are responsible for hard-to-treat MLL leukemia – and that it's possible to reverse this process.

Tags: BasicResearch, ChildhoodCancer

  • Dana-Farber researchers show first large-scale map of protein networks in a plant, addressing longstanding questions about evolution and illuminating disease processes in plants, in turn broadening the understanding of the basic functioning of human cells.

Tags: BasicResearch

  • In an elegant, multiple-gene knockout experiment, a team of Boston scientists has discovered that a trio of molecules, called FoxOs, are fundamentally critical in preventing some cancers, maintaining blood vessel stability, and in keeping blood-forming stem cells healthy.

Tags: BasicResearch

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