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News tagged ‘Genomics’ clear

  • Dana-Farber and the Broad Institute researchers have found high levels of the bacterium Fusobacterium in colorectal cancers, a sign that it might contribute to the disease and potentially lead to further research.

Tags: BasicResearch, ColonCancer, Genomics

  • A new discovery by Jean Zhao, PhD, and colleagues may help physicians predict which tumors are likely to become resistant to a given drug. In the report, published by Nature Medicine, researchers described how they created a genetically engineered mouse model of human breast cancer in which the most frequently occurring breast cancer oncogene, PIK3CA, could be turned on and off.

Tags: BreastCancer, Genomics, TargetedTherapy, Genetics

  • Kornelia Polyak, MD, PhD, and colleagues identified a network of growth-spurring genes that drive stem-like breast cancer cells enriched in triple-negative breast tumors.

Tags: BreastCancer, Genomics

  • Researchers from the Broad Institute, Dana-Farber Cancer Institute and Weill Cornell Medical College have laid bare the full genetic blueprint of multiple prostate tumors, uncovering alterations that have never before been detected and offering a deep view of the genetic missteps that underlie the disease.

Tags: Genomics, ProstateCancer

  • A team of scientists led by Dana-Farber has created the first molecule able to control gene activity in cancer.

Tags: Genomics, TargetedTherapy

  • Dr. Gimelbrant is mapping gene activation to better understand the mechanisms essential for gene silencing. His findings could lead to the design of highly customized cancer treatments.

Tags: BasicResearch, Genomics

  • Study finds similarities in genetic characteristics of different tumor types, which could lead to common strategies for treating them.

Tags: BasicResearch, Genomics

  • Researchers working in genomics and molecular biology have demonstrated that a surplus of a gene known as GOLPH3 can spur cancer cell growth.

Tags: Genomics, Genetics

  • A collaborative study involving Dana-Farber researchers has unearthed a variety of genetic alterations in lung tumors, more than doubling the number already linked to the disease.

Tags: Genomics, LungCancer

  • A genetic survey of glioblastoma reveals a variety of broken, missing, and overactive genes, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

Tags: BasicResearch, Genomics, BrainTumors

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