News tagged ‘BasicResearch’ clear
Scientists from Brigham and Women's Hospital and Dana-Farber Cancer Institute and their colleagues have found a genetic marker that predicts which aggressive "triple negative" breast cancers and certain ovarian cancers will likely respond to platinum-based chemotherapies.
Tags: BasicResearch, BreastCancer, Genomics, OvarianCancer, GynecologicCancers
Genetic specialists at Dana-Farber/Children’s Hospital Cancer Center (DF/CHCC) are recommending that children being treated for sarcoma should be offered genetic counseling for Li-Fraumeni syndrome, a rare condition that greatly raises a person’s risk of developing additional cancers
Tags: BasicResearch, Genomics, Sarcoma
The Massachusetts Life Sciences Center has awarded Dana-Farber Cancer Institute a $10 million grant to support the expansion of its pioneering cancer imaging research program with a new imaging facility which will support more rapid assessment of therapies and play a key role in the delivery of personalized medicine.
Tags: BasicResearch, Grants, TargetedTherapy, Imaging
In a paper published online yesterday by the journal Nature, Dana-Farber researchers map out a mechanism by which micronuclei could potentially disrupt the chromosomes within them and produce cancer-causing gene mutations. The findings may point to a vulnerability in cancer cells that could be attacked by new therapies.
Tags: BasicResearch, Genomics
Researchers have isolated a natural hormone from muscle cells that triggers some of the key health benefits of exercise. Irisin, which switches on genes that convert white fat into "good" brown fat, may hold promise as a novel treatment for diabetes, obesity and perhaps other disorders, including cancer.
Tags: BasicResearch, Exercise, Hormones
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A study documents the connection between increased levels of epoxyeicosatrienoic acids (EET) lipids and cancer growth and metastasis opening the door to a new avenue for cancer treatment.
Tags: BasicResearch
"Twinning" U.S.-based and Rwandan physicians in a team approach has shown to improve lymphoma outcomes in children in a country lacking any specialists in children's cancers.
Tags: BasicResearch, ChildhoodCancer, Lymphoma
Scientists at Dana-Farber Cancer Institute have identified a gene mutation that underlies the vast majority of cases of Waldenström's macroglobulinemia, a rare form of lymphoma that has eluded all previous efforts to find a genetic cause.
Tags: BasicResearch, Lymphoma
Scientists have created a "cocktail" combination of four antigenic peptides derived from myeloma cells they believe could provoke the body's defenses to attack multiple myeloma in its early "smoldering" phase and slow or prevent the blood cancer.
Tags: BasicResearch, MultipleMyeloma
A therapy involving a natural compound may improve the ability of stem cells from umbilical cord blood to engraft in patients receiving a stem cell transplant for cancer or other diseases.
Tags: BasicResearch, StemCellTransplant
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