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News tagged ‘ChildhoodCancer’ clear

  • Boston Mayor Martin Walsh reflected on his successful fight against childhood lymphoma at Dana-Farber’s annual celebration of survivorship. He was diagnosed at age 7 with Burkitt’s lymphoma, a rare, aggressive form of non-Hodgkin lymphoma that primarily affects children.

Tags: ChildhoodCancer, Survivorship

  • One of the first studies to analyze the effectiveness of screening survivors of childhood cancer for early signs of impending congestive heart failure (CHF) finds improved health outcomes but suggests that less frequent screening than currently recommended may yield similar clinical benefit.

Tags: ChildhoodCancer, Survivorship

  • Researchers studying a rare, always fatal brain tumor in children have found several molecular alterations that drive the cancer, according to a new study from scientists at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and McGill University. The findings, published in Nature Genetics, identify potential new targets for drug treatments.

Tags: ChildhoodCancer, Genomics, TargetedTherapy, BrainTumors

  • A normal enzyme called SYK pairs with FLT3, the most commonly mutated enzyme found in acute myelogenous leukemia, to promote progression of the cancer and its resistance to treatment with FLT3-blocking drugs, which may explain relatively poor results in clinical studies. In a mouse model, treatment with a combination of drugs to inhibit the two enzymes was more effective than treatment with either drug alone.

Tags: chemotherapy, BasicResearch, ChildhoodCancer, Leukemia

  • Almost 90 percent of children treated for low-grade gliomas are alive 20 years later and few die from the tumor as adults. However, children whose treatment included radiation had significantly lower long-term survival rates.

Tags: ChildhoodCancer, Radiation, BrainTumors

  • Children with acute lymphoblastic leukemia (ALL), the most common form of pediatric cancer, can safely receive intravenous infusions of a reformulated mainstay of chemotherapy that has been delivered via painful intramuscular injection for more than 40 years, research suggests.

Tags: chemotherapy, ChildhoodCancer, Leukemia

  • Some babies diagnosed with and treated for a bone marrow failure disorder, called Diamond Blackfan Anemia, may actually be affected by a very rare anemia syndrome that has a different disease course and treatment, say scientists from Dana-Farber/Boston Children's Cancer and Blood Disorders Center.

Tags: ChildhoodCancer

  • Dana-Farber/Boston Children's researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated in an international clinical study of a new form of gene therapy.

Tags: ChildhoodCancer, ImmuneSystem, Genetics, Leukemia

  • New research shows that although women who survived childhood cancer face an increased risk of infertility, nearly two-thirds of those who tried unsuccessfully to become pregnant for at least a year eventually conceived.

Tags: ChildhoodCancer, Survivorship

  • A type of low-grade but sometimes lethal brain tumor in children has been found to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors.

Tags: ChildhoodCancer, BrainTumors

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