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News tagged ‘Genomics’ clear

  • New findings on prostate cancer from The Cancer Genome Atlas may enable doctors to make better diagnoses and prognoses for patients and provide novel directions for therapies.

Tags: Genomics, ProstateCancer

  • Turning off a single gene leads to a roughly three-to-five-fold gain in the yield of laboratory methods for producing red blood cells from stem cells, according to new research published in Cell Stem Cell. The findings suggest a way to cost-effectively manufacture red blood cells from stem cells; the patients who could potentially benefit include those who cannot use blood currently available in blood banks.

Tags: BasicResearch, ChildhoodCancer, Genomics

  • A new study charts the "genomic biography" of chronic lymphocytic leukemia, identifying gene mutations driving its growth, and tracing the shift in mutations as the disease progresses and develops resistance to chemotherapy, demonstrating the power of sequencing DNA in a large group of tumor tissue samples.

Tags: Genomics, Leukemia

  • Dana-Farber scientists and colleagues use genome- and epigenome-editing tools to pinpoint disease-causing variants.

Tags: BasicResearch, Genomics

  • Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center, using CRISPR-based gene editing techniques, have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell disease (SCD), according to a study published in the journal Nature.

Tags: Genomics, Genetics

  • In a new study published in Nature, Dana-Farber scientists demonstrate how a sudden, isolated shuffling of genetic material — known as chromothripsis — can occur.

Tags: BasicResearch, Genomics

  • First study of the genomic composition of prostate cancer shows many patients have gene mutations that can be targeted with existing or potential drugs.

Tags: Genomics, ProstateCancer, TargetedTherapy

  • Dana-Farber/Brigham and Women's Cancer Center has a new website to connect patients and physicians with information about precision cancer medicine, including resources on what precision cancer is and how it can be applied to cancer care today.

Tags: BasicResearch, Genomics

  • Dana-Farber's Levi Garraway, MD, PhD, has been selected as one of 26 Howard Hughes Medical Institute investigators.

Tags: Genomics, Honors, ProstateCancer

  • Websites that market personalized cancer care services often overemphasize their purported benefits and downplay their limitations, and many sites offer genetic tests whose value for guiding cancer treatment has not been shown to be clinically useful, according to a new study from Dana-Farber Cancer Institute.

Tags: Genomics, Genetics

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