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News tagged ‘BrainTumors’ clear

  • The drug lapatinib shrank tumors and slowed progression of brain metastases in some patients with advanced breast cancer, according to results of a clinical trial being presented by Dana-Farber Cancer Institute scientists at the annual meeting of the American Society of Clinical Oncology.

Tags: BrainTumors

  • Researchers at Dana-Farber Cancer Institute have shown that several, rather than just one, cell-growth switches are simultaneously overactive in many brain tumors and other solid tumors, explaining why treatment with just a single "targeted" switch-blocking drug often yields disappointing results.

Tags: BrainTumors

  • A combination of a "targeted" therapy and chemotherapy shrank metastatic brain tumors by at least 50 percent in one-fifth of patients with aggressive HER2-positive breast cancer, according to data presented by Dana-Farber investigators at the San Antonio Breast Cancer Symposium.

Tags: BreastCancer, BrainTumors

  • The search for cancer genes is increasingly a matter of molecular "To Tell the Truth," as scientists seek to distinguish genes actually involved in the disease from those that are imposters.

Tags: Genomics, BrainTumors

  • New study shows medulloblastomas originate in cells that turn malignant when acted on by a cancer-causing oncogene.

Tags: ChildhoodCancer, BrainTumors

  • A genetic survey of glioblastoma reveals a variety of broken, missing, and overactive genes, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

Tags: BasicResearch, Genomics, BrainTumors

  • Dana-Farber/Children's Hospital Cancer Center researchers have linked genetic mutations to each of the four recognized subtypes of medulloblastoma, the most common malignant brain tumor of children.

Tags: BasicResearch, ChildhoodCancer, Genomics, BrainTumors

  • Scientists from Dana-Farber and the Broad Institute have identified two DNA mutations that appear to drive about 15 percent of meningiomas, a finding that could lead to the first effective drug treatments for the brain tumor.

Tags: TargetedTherapy, BrainTumors

  • A type of low-grade but sometimes lethal brain tumor in children has been found to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors.

Tags: ChildhoodCancer, BrainTumors

  • Dana-Farber researchers have used a novel combination of two oral targeted drugs to dramatically slow the growth of glioblastoma brain tumors in mice, which significantly extended the animals’ survival.

Tags: Genetics, BrainTumors

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