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News tagged ‘BasicResearch’ clear

  • Researchers found a way of differentiating angiocentric gliomas from other low-grade pediatric brain tumors and developed a pathological test that will help children avoid unnecessary and potentially damaging additional therapies.

Tags: BasicResearch, ChildhoodCancer, BrainTumors

  • Research by Dana-Farber scientists reveals genes with monoallelic expression are an important source of genetic diversity among people and also may help explain the genetic variation among cancer cells in a tumor.

Tags: BasicResearch, Genetics

  • Dana-Farber researchers identify an overactive genetic regulator that could aid in developing strategies to combat drug resistance in ovarian cancer.

Tags: BasicResearch, OvarianCancer, GynecologicCancers

  • Dana-Farber researchers uncover first potential targeted drug for triple-negative breast cancer as well as vulnerability that could be exploited to slow or prevent the development of resistance to BET-inhibiting drugs.

Tags: BasicResearch, BreastCancer

  • In a span of five weeks beginning in late October, the U.S. Food and Drug Administration (FDA) gave approval to five new cancer drugs that proved effective in Dana-Farber-led clinical trials – and, in some cases, derive from basic research in Dana-Farber laboratories.

Tags: chemotherapy, BasicResearch, LungCancer, MultipleMyeloma, Sarcoma

  • The Commonwealth Foundation for Cancer Research has pledged $20 million to the Bridge Project, a collaborative research program of the Koch Institute for Integrative Cancer Research at MIT and Dana-Farber/Harvard Cancer Center, to accelerate the translation of interdisciplinary cancer solutions toward the clinic.

Tags: BasicResearch

  • Turning off a single gene leads to a roughly three-to-five-fold gain in the yield of laboratory methods for producing red blood cells from stem cells, according to new research published in Cell Stem Cell. The findings suggest a way to cost-effectively manufacture red blood cells from stem cells; the patients who could potentially benefit include those who cannot use blood currently available in blood banks.

Tags: BasicResearch, ChildhoodCancer, Genomics

  • New research by Dana-Farber Cancer Institute scientists raises the prospect of cancer therapy that works by converting a tumor's best friends in the immune system into its gravest enemies.

Tags: BasicResearch, Immunotherapy

  • Researchers link early prostate cancer to alterations in a program controlled by a "master regulator" of cell growth. This insight could open new avenues for preventing and treating prostate cancer.

Tags: BasicResearch, ProstateCancer

  • Dana-Farber scientists and colleagues use genome- and epigenome-editing tools to pinpoint disease-causing variants.

Tags: BasicResearch, Genomics

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