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News tagged ‘BrainTumors’ clear

  • Dana-Farber researchers have used a novel combination of two oral targeted drugs to dramatically slow the growth of glioblastoma brain tumors in mice, which significantly extended the animals’ survival.

Tags: Genetics, BrainTumors

  • Researchers at Dana-Farber Cancer Institute have shown that several, rather than just one, cell-growth switches are simultaneously overactive in many brain tumors and other solid tumors, explaining why treatment with just a single "targeted" switch-blocking drug often yields disappointing results.

Tags: BrainTumors

  • Researchers studying a rare, always fatal brain tumor in children have found several molecular alterations that drive the cancer, according to a new study from scientists at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and McGill University. The findings, published in Nature Genetics, identify potential new targets for drug treatments.

Tags: ChildhoodCancer, Genomics, TargetedTherapy, BrainTumors

  • A type of low-grade but sometimes lethal brain tumor in children has been found to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors.

Tags: ChildhoodCancer, BrainTumors

  • An altered radiation treatment schedule for the most common and lethal form of brain cancer extended survival times a new study by researchers at Dana-Farber Cancer Institute and other organizations has shown.

Tags: Radiation, BrainTumors

  • The search for cancer genes is increasingly a matter of molecular "To Tell the Truth," as scientists seek to distinguish genes actually involved in the disease from those that are imposters.

Tags: Genomics, BrainTumors

  • Scientists have identified a mutated gene that causes a type of benign brain tumor that can have devastating lifelong effects. It may be possible to attack the tumors with targeted drugs already in use for other tumors.

Tags: TargetedTherapy, BrainTumors

  • A genetic survey of glioblastoma reveals a variety of broken, missing, and overactive genes, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

Tags: BasicResearch, Genomics, BrainTumors

  • Almost 90 percent of children treated for low-grade gliomas are alive 20 years later and few die from the tumor as adults. However, children whose treatment included radiation had significantly lower long-term survival rates.

Tags: ChildhoodCancer, Radiation, BrainTumors

  • Dana-Farber/Children's Hospital Cancer Center researchers have linked genetic mutations to each of the four recognized subtypes of medulloblastoma, the most common malignant brain tumor of children.

Tags: BasicResearch, ChildhoodCancer, Genomics, BrainTumors

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