News tagged ‘BrainTumors’ clear
- Researchers at Dana-Farber Cancer Institute have shown that
several, rather than just one, cell-growth switches are simultaneously
overactive in many brain tumors and other solid tumors, explaining why
treatment with just a single "targeted" switch-blocking drug often
yields disappointing results.
Tags: BrainTumors
A type of low-grade but sometimes lethal brain tumor in children has been found to contain an unusual mutation that may help to classify, diagnose and guide the treatment of the tumors.
Tags: BasicResearch, ChildhoodCancer, BrainTumors
- The search for cancer genes is increasingly a matter of molecular
"To Tell the Truth," as scientists seek to distinguish genes actually
involved in the disease from those that are imposters.
Tags: Genomics, BrainTumors
- A genetic survey of glioblastoma reveals a variety of broken, missing,
and overactive genes, report scientists from Dana-Farber Cancer
Institute and the Broad Institute of MIT and Harvard.
Tags: BasicResearch, Genomics, BrainTumors
Dana-Farber/Children's Hospital Cancer Center researchers have linked genetic mutations to each of the four recognized subtypes of medulloblastoma, the most common malignant brain tumor of children.
Tags: BasicResearch, ChildhoodCancer, Genomics, BrainTumors
Justin Bieber's date with young brain tumor patient Avalanna Routh has focused attention on atypical teratoid rhabdoid tumor, or AT/RT. Mark Kieran, MD, PhD, of Dana-Farber/Children's Hospital Cancer Center, discusses this rare cancer.
Tags: ChildhoodCancer, BrainTumors
Scientists from Dana-Farber and the Broad Institute have identified two DNA mutations that appear to drive about 15 percent of meningiomas, a finding that could lead to the first effective drug treatments for the brain tumor.
Tags: BasicResearch, TargetedTherapy, BrainTumors
- The drug lapatinib shrank tumors and slowed progression of brain
metastases in some patients with advanced breast cancer, according to
results of a clinical trial being presented by Dana-Farber Cancer
Institute scientists at the annual meeting of the American Society of
Clinical Oncology.
Tags: BrainTumors
- A combination of a "targeted" therapy and chemotherapy shrank metastatic
brain tumors by at least 50 percent in one-fifth of patients with
aggressive HER2-positive breast cancer, according to data presented by
Dana-Farber investigators at the San Antonio Breast Cancer Symposium.
Tags: BreastCancer, BrainTumors
- New study shows medulloblastomas originate in cells that turn malignant when acted on by a cancer-causing oncogene.
Tags: ChildhoodCancer, BrainTumors