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News tagged ‘BreastCancer’ clear

  • A survey of young women with breast cancer found that many often overestimate the odds that cancer will occur in their other, healthy breast, and decide to have the healthy breast surgically removed even though most understood that removing both breasts does not extend their survival.

Tags: BreastCancer

  • A Dana-Farber and Harvard School of Public Health study finds that most young women with breast cancer chose to have a mastectomy rather than a surgical procedure that would conserve the breast.

Tags: BreastCancer, PopulationScience

  • Cancer death rates in the United States continue to decline, according to the Annual Report to the Nation on the Status of Cancer, published online by the journal Cancer.

Tags: BreastCancer, ColonCancer, LungCancer, Prevention

  • Dana-Farber scientists have safely shut down breast cancer and a form of leukemia in mice by targeting abnormal proteins to which the cancers are "addicted."

Tags: BasicResearch, BreastCancer, Leukemia

  • Pre-menopausal breast cancer survivors who were treated with chemotherapy following surgery were more likely to have diminished ovarian reserve compared to women who have never had breast cancer, according to a study led by Dana-Farber investigators.

Tags: BreastCancer

  • Dana-Farber scientists have linked genetic variants to the regulation of genes involved in breast cancer, including four genes not previously implicated in breast cancer, shedding new insights into the biology of breast cancer.

Tags: BreastCancer, Genomics

  • A Dana-Farber study challenges the hypothesis that "cancer stem cells" — a small number of self-renewing cells within a tumor — are responsible for breast cancer progression and recurrence, and that wiping out these cells alone could cure the disease.

Tags: BreastCancer, StemCellTransplant

  • Although it sounds like a case of gender confusion on a molecular scale, the male hormone androgen spurs the growth of some breast tumors in women. In a new study, scientists at Dana-Farber Cancer Institute provide the first details of the cancer cell machinery that carries out the hormone’s relentless growth orders.

Tags: BasicResearch, BreastCancer

  • A new discovery by Jean Zhao, PhD, and colleagues may help physicians predict which tumors are likely to become resistant to a given drug. In the report, published by Nature Medicine, researchers described how they created a genetically engineered mouse model of human breast cancer in which the most frequently occurring breast cancer oncogene, PIK3CA, could be turned on and off.

Tags: BreastCancer, Genomics, TargetedTherapy, Genetics

  • Dana-Farber scientists find when given together, two orally available experimental drugs – sapacitabine and seliciclib – worked together to elicit antitumor effects in patients with incurable BRCA-deficient cancers.

Tags: BasicResearch, BreastCancer, PancreaticCancer, GynecologicCancers

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