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News tagged ‘Genetics’ clear

  • Dana-Farber researchers have used a novel combination of two oral targeted drugs to dramatically slow the growth of glioblastoma brain tumors in mice, which significantly extended the animals’ survival.

Tags: Genetics, BrainTumors

  • A study led by researchers at Dana-Farber Cancer Institute and Broad Institute of the Massachusetts Institute of Technology and Harvard University provides the first demonstration of a practical method of screening tumors for cancer-related gene abnormalities that might be treated with "targeted" drugs.

Tags: BasicResearch, Genomics, Genetics

  • Scientists at Dana-Farber Cancer Institute have shown in a laboratory study that revving up a crucial set of muscle genes counteracts the damage caused by a form of muscular dystrophy.

Tags: Genomics, Genetics

  • Dana-Farber and Broad Institute researchers for the first time are able to show the past, present, and future of CLL tumors.

Tags: Genetics, Leukemia

  • Deprived of androgen hormones, the receptor finds an alternative genetic pathway to continue growth of prostate cancer cells. An understanding of this behavior could lead to new therapies targeting specific genes.

Tags: BasicResearch, ProstateCancer, Genetics

  • Researchers working in genomics and molecular biology have demonstrated that a surplus of a gene known as GOLPH3 can spur cancer cell growth.

Tags: Genomics, Genetics

  • A new discovery by Jean Zhao, PhD, and colleagues may help physicians predict which tumors are likely to become resistant to a given drug. In the report, published by Nature Medicine, researchers described how they created a genetically engineered mouse model of human breast cancer in which the most frequently occurring breast cancer oncogene, PIK3CA, could be turned on and off.

Tags: BreastCancer, Genomics, TargetedTherapy, Genetics

  • Nine-fold higher pancreatic cancer risk suggests people with this genetic syndrome should be closely monitored.

Tags: ProstateCancer, Genetics

  • A new study by researchers at Dana-Farber Cancer Institute shows a half-day educational program can help women successfully deal with side effects of ovary removing surgery as a cancer prevention measure.

Tags: OvarianCancer, Genetics

  • Dana-Farber researchers have found that the basic cause of age-related health decline is malfunctioning telomeres — the end-caps on cells' chromosomes that protect them against DNA damage.

Tags: ImmuneSystem, Genetics

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