News tagged ‘ImmuneSystem’ clear
- Answering one of the oldest questions in human physiology, researchers
at Dana-Farber have discovered why the body's immune system —
perpetually on guard against foreign microbes like bacteria — doesn't
attack tissues in the small intestine that harbor millions of bacteria
- Dana-Farber scientists report in the Journal of Clinical Investigation they have developed a tumor vaccine based on the patient’s tumor to create a strong and selective immune response in some chronic lymphocytic leukemia patients.
Tags: ImmuneSystem, Leukemia
- A section of the AIDS virus's protein envelope known as the V3 loop and
once considered an improbable target for a vaccine now appears to be one
of the most promising, according to research authored by Dana-Farber's
Ruth Ruprecht, MD, PhD.
Tags: BasicResearch, ImmuneSystem
- Dana-Farber researchers have found that the basic cause of age-related
health decline is malfunctioning telomeres — the end-caps on cells'
chromosomes that protect them against DNA damage.
Tags: ImmuneSystem, Genetics
- Dana-Farber scientists have identified a protein that prevents the
body's immune system from recognizing and attacking Hodgkin lymphoma
cells. Based on this finding, the researchers are now investigating
targeted therapies to disable this molecular "bodyguard" and boost a
patient's ability to fight the blood cancer.
Tags: BasicResearch, ImmuneSystem, Lymphoma
- A clinical trial for advanced melanoma caused growths to recede or stabilize in half of the participants by blocking a protein interaction that prevents T cells from attacking cancerous cells, reports lead author Stephen Hodi, MD.
Tags: ImmuneSystem, Melanoma
- Dana-Farber scientists have demonstrated a new strategy for treating autoimmune disease that successfully blocked the development of rheumatoid arthritis in a mouse model. They say it holds promise for improved treatment of arthritis and other autoimmune disorders in people.
- In a study that seems to pivot on a paradox, scientists at Dana-Farber Cancer Institute have used an immune system stimulant as an immune system suppressor to treat a common, often debilitating side effect of donor stem cell transplantation in cancer patients.
Tags: BasicResearch, GraftVersusHost, ImmuneSystem
- The immune system's ability to police itself may offer a new method of
arresting the cells responsible for autoimmune diseases such as multiple
sclerosis and for the rejection of transplanted organs and tissues,
scientists at Dana-Farber report in a study in the May issue of the
- Dana-Farber/Boston Children's researchers reported promising outcomes data for the first group of boys with X-linked severe combined immunodeficiency syndrome (SCID-X1), a fatal genetic immunodeficiency also known as "bubble boy" disease, who were treated in an international clinical study of a new form of gene therapy.
Tags: ChildhoodCancer, ImmuneSystem, Genetics, Leukemia