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News tagged ‘Genetics’ clear

  • Myles Brown, MD, Brown, director of the Center for Functional Cancer Epigenetics at Dana-Farber Cancer Institute, has been elected to The National Academy of Sciences.

Tags: Appointments, Honors, Genetics

  • An overwhelming majority of people with incurable cancer want to hear findings from DNA sequencing of their own tumors and normal cells, and to learn how those results may affect their health and treatment options, Dana-Farber Cancer Institute scientists report.

Tags: Genetics

  • An international collaboration of organizations, including Dana-Farber Cancer Institute, has reached a milestone in creating a library of complete genetic blueprints for the thousands of different proteins in human cells.

Tags: Genetics

  • How well a flu shot protects you from the virus can depend on your ethnic background and other inherited factors, report Dana-Farber scientists.

Tags: Influenza, Genetics

  • In a first large-scale systematic study led by researchers at Dana-Farber, scientists found that most sibling proteins – known as "protein isoforms" encoded by the same gene – often play radically different roles within tissues and cells, however alike they may be structurally.

Tags: Genomics, Genetics

  • In a new study, Dana-Farber researchers find that BRCA1 and BRCA2 testing for young women with breast cancer reaches new high levels. Results of these genetic tests are increasingly used to guide treatment and many who don’t carry such mutations still opt for bilateral mastectomy.

Tags: BreastCancer, Genetics

  • Clinical genomic sequencing is feasible in pediatric oncology and can be used to recommend therapy or pinpoint diagnosis in children with solid tumors according to research led by Dana-Farber/Boston Children's Cancer and Blood Disorders Center. The findings, published in JAMA Oncology, represent a significant step in making precision medicine available to children with cancer.

Tags: ChildhoodCancer, TargetedTherapy, Genetics

  • Research by Dana-Farber scientists reveals genes with monoallelic expression are an important source of genetic diversity among people and also may help explain the genetic variation among cancer cells in a tumor.

Tags: BasicResearch, Genetics

  • Researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center, using CRISPR-based gene editing techniques, have found that changes to a small stretch of DNA may circumvent the genetic defect behind sickle cell disease (SCD), according to a study published in the journal Nature.

Tags: Genomics, Genetics

  • A study led by Pasi Jänne, MD, PhD, found that an experimental drug targeted to the resistance mutation is highly active in patients with EGFR-positive non-small cell lung cancer (NSCLC) when the disease progressed during treatment with front-line inhibitor drugs.

Tags: LungCancer, Genetics

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