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News tagged ‘TranslationalResearch’ clear

  • Dana-Farber researchers report that combination treatment with olaparib and BKM120 was safe and yielded evidence of clinical benefit for women with triple-negative breast cancer and for those with high-grade serous ovarian cancer in a phase I clinical trial.

Tags: OvarianCancer, TranslationalResearch

  • Dana-Farber's Alan D'Andrea, MD, has been selected to lead a Stand Up To Cancer Dream Team devoted to ovarian cancer research. The team will focus on DNA repair therapies for ovarian cancer.

Tags: OvarianCancer, TranslationalResearch

  • Dana-Farber researchers report in the New England Journal of Medicine that ibrutinib, a newly approved drug for Waldenström's Macroglobulinemia, continues to control the rare blood cancer, with 95 percent of patients surviving for two years.

Tags: TargetedTherapy, TranslationalResearch, Lymphoma

  • Dana-Farber Cancer Institute is expanding its research footprint by moving into five floors at Longwood Center (360 Longwood Avenue), beginning later this month.

Tags: BasicResearch, TranslationalResearch

  • In a major advance in the care of patients with leukemia and other blood disorders, physicians at Dana-Farber/Brigham and Women's Cancer Center have begun using Rapid Heme Panel, a high-tech genetic test that provides, within a matter of days, an unprecedented amount of critical information to aid the choice of treatment.

Tags: StemCellTransplant, TranslationalResearch, Leukemia

  • Sequencing a patient's tumor before and after a clinical trial yielded information on why the tumor responded to and eventually resisted treatment, identifying mutations that may help guide the treatment of patients with cancers with similar mutations.

Tags: TranslationalResearch, HeadNeckCancers

  • Dana-Farber researchers have demonstrated that a hormone-depleting drug can help eliminate or nearly eliminate aggressive prostate cancers that have yet to spread beyond the prostate.

Tags: Hormones, ProstateCancer, TranslationalResearch

  • A multi-institutional team of researchers has published a study that demonstrates a novel therapy works against solid tumors. It is the first targeted and programmed nanomedicine to enter human clinical studies.

Tags: TargetedTherapy, TranslationalResearch

  • By conducting simultaneous clinical trials in patients and labs, Dana-Farber researchers and colleagues have been able to predict how patients with non-small cell lung cancer respond to combination therapy.

Tags: LungCancer, TranslationalResearch

  • Jessie M. English, PhD, has been appointed the head of Research of the Belfer Institute for Applied Cancer Science at Dana-Farber. The Belfer Institute offers the full array of innovative drug discovery capabilities, from the identification of cancer-causing genetic mutations to the validation and selection of new drug targets.

Tags: Genomics, LungCancer, TargetedTherapy, TranslationalResearch

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